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Lingzhong Meng, M.D.

Anesthesiologist

Education

Peking Union Medical University 1997

Residencies

University of Miami Jackson Memorial Hospital 2006
University of California Los Angeles Medical Center 2008

Selected Research and Publications

  1. Meng L, Gelb AW, McDonagh DL. Changes in cerebral tissue oxygen saturation during anaesthetic-induced hypotension: an interpretation based on neurovascular coupling and cerebral autoregulation. Anaesthesia. 2013 Jul; 68(7):736-41.
  2. Alexander BS, Gelb AW, Mantulin WW, Cerussi AE, Tromberg BJ, Yu Z, Lee C, Meng L. Impact of stepwise hyperventilation on cerebral tissue oxygen saturation in anesthetized patients: a mechanistic study. Acta Anaesthesiol Scand. 2013 May; 57(5):604-12.
  3. Chen G, Meng L, Alexander B, Tran NP, Kain ZN, Cannesson M. Comparison of noninvasive cardiac output measurements using the Nexfin monitoring device and the esophageal Doppler. J Clin Anesth. 2012 Jun; 24(4):275-83.
  4. Meng L, Gelb AW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Mantulin WW. Impact of phenylephrine administration on cerebral tissue oxygen saturation and blood volume is modulated by carbon dioxide in anaesthetized patients. Br J Anaesth. 2012 May; 108(5):815-22.
  5. Chen G, Chung E, Meng L, Alexander B, Vu T, Rinehart J, Cannesson M. Impact of non invasive and beat-to-beat arterial pressure monitoring on intraoperative hemodynamic management. J Clin Monit Comput. 2012 Apr; 26(2):133-40.
  6. Meng L, Mantulin WW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Laning K, Kain ZN, Cannesson M, Gelb AW. Head-up tilt and hyperventilation produce similar changes in cerebral oxygenation and blood volume: an observational comparison study using frequency-domain near-infrared spectroscopy. Can J Anaesth. 2012 Apr; 59(4):357-65.
  7. Meng L, Tran NP, Alexander BS, Laning K, Chen G, Kain ZN, Cannesson M. The impact of phenylephrine, ephedrine, and increased preload on third-generation Vigileo-FloTrac and esophageal doppler cardiac output measurements. Anesth Analg. 2011 Oct; 113(4):751-7.
  8. Meng L, Cannesson M, Alexander BS, Yu Z, Kain ZN, Cerussi AE, Tromberg BJ, Mantulin WW. Effect of phenylephrine and ephedrine bolus treatment on cerebral oxygenation in anaesthetized patients. Br J Anaesth. 2011 Aug; 107(2):209-17.
  9. Asouhidou I, Katsaridis V, Meng L, Zilianaki D, Vaidis G, Ioannou P, Georgiadis G. Desaturation during Onyx embolization. Br J Anaesth. 2010 Sep; 105(3):385-6.
  10. Meng L, Wu Z, Wang Y, Lassman C, Busuttil RW, Zhai Y, Kupiec-Weglinski JW. Differential impact of CD154 costimulation blockade on alloreactive effector and regulatory T cells in murine renal transplant recipients. Transplantation. 2008 May 15; 85(9):1332-8.
  11. Zhai Y, Meng L, Gao F, Wang Y, Busuttil RW, Kupiec-Weglinski JW. CD4+ T regulatory cell induction and function in transplant recipients after CD154 blockade is TLR4 independent. J Immunol. 2006 May 15; 176(10):5988-94.
  12. Zheng SG, Meng L, Wang JH, Watanabe M, Barr ML, Cramer DV, Gray JD, Horwitz DA. Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient. Int Immunol. 2006 Feb; 18(2):279-89.
  13. Carmody IC, Meng L, Shen XD, Anselmo D, Gao F, Ke B, Ma JP, Kupiec-Weglinski JW, McDiarmid SV, Busuttil RW, Shaw G, Farmer DG. P-selectin knockout mice have improved outcomes with both warm ischemia and small bowel transplantation. Transplant Proc. 2004 Mar; 36(2):263-4.
  14. Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, Ishikawa K, Iyer S, Buelow R, Busuttil RW, Shih DM, Lusis AJ, Kupiec-Weglinski JW. Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. J Immunol. 2003 Aug 1; 171(3):1572-80.
  15. Zhai Y, Meng L, Busuttil RW, Sayegh MH, Kupiec-Weglinski JW. Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive. J Immunol. 2003 Mar 15; 170(6):3024-8.
  16. Zhai Y, Meng L, Gao F, Busuttil RW, Kupiec-Weglinski JW. Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients. J Immunol. 2002 Oct 15; 169(8):4667-73.
  17. Coito AJ, Shaw GD, Meng L, Moore C, Ma J, Busuttil RW, Kupiec-Weglinski JW. CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients. Transplant Proc. 2002 Aug; 34(5):1463-4.
  18. Guo Z, Wang J, Meng L, Wu Q, Kim O, Hart J, He G, Zhou P, Thistlethwaite JR, Alegre ML, Fu YX, Newell KA. Cutting edge: membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection. J Immunol. 2001 Nov 1; 167(9):4796-800.
  19. Guo Z, Meng L, Kim O, Wang J, Hart J, He G, Alegre ML, Thistlethwaite JR, Pearson TC, Larsen CP, Newell KA. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation. 2001 May 15; 71(9):1351-4.
  20. Meng L, Guo Z, Kim O, He G, Hart J, Szot GL, Wang J, Pearson TC, Larsen CP, Newell KA. Blockade of the CD40 pathway fails to prevent CD8 T cell-mediated intestinal allograft rejection. Transplant Proc. 2001 Feb-Mar; 33(1-2):418-20.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.