Malcolm John, MD

Director of the HIV/AIDS Program

Dr. Malcolm John, an expert in infectious diseases, is director of the UCSF HIV/AIDS Program at UCSF Medical Center, one of the most comprehensive HIV and AIDS treatment programs in the country. In addition to his work at UCSF, John is an HIV consultant at the Larkin Street Youth Center in San Francisco.

John's research addresses molecular and immunologic components of diseases associated with the human papillomavirus (HPV) in HIV-infected patients, particularly among African Americans. He also studies differences in HIV care, treatment and outcomes among African Americans.

John earned a medical degree at Harvard University and a graduate degree in public health at the University of California at Berkeley. He completed an infectious disease fellowship at UCSF, where he was a postdoctoral fellow in the Center for AIDS Prevention Studies. He has received numerous awards, including the Robert Wood Johnson Harold Amos Faculty Development Award. He is a professor in the department of medicine.

  • Read a Q&A with John about pre-exposure prophylaxis, better known as PrEP, a prevention pill for people who don't have HIV but are at substantial risk of infection.


HIV/AIDS Program
350 Parnassus Avenue, Suite 908
San Francisco, CA 94143
Phone: (415) 353-2119
Fax: (415) 353-2406

Hours: Monday to Thursday
8:30 a.m. – noon, 1 – 5 p.m.

Conditions & Treatments

Board Certification

Infectious Disease

More about Malcolm John

Additional Languages



Harvard Medical School 1994


Massachusetts General Hospital, Internal Medicine 1995


Massachusetts General Hospital, Internal Medicine 1997
UCSF, Infectious Diseases 2000

Selected Research and Publications

  1. Greene M, Hessol NA, Perissinotto C, Zepf R, Hutton Parrott A, Foreman C, Whirry R, Gandhi M, John M. Loneliness in Older Adults Living with HIV. AIDS Behav. 2017 Nov 18.
  2. Hessol NA, Zepf R, Zobell E, Weiser SD, John MD. Food Insecurity and Aging Outcomes in Older Adults Living with HIV. AIDS Behav. 2017 Jun 26.
  3. Jessica Y Rhee, Eric J Chan, Paul M Elizondo III, James A Bourgeois, Cameron W Foreman, Lisa Dazols, Jorien G Breur, Joseph K Shemuel, Amanda R Martin, Sharonya Shrivastava, Isabel E Allen and Malcolm D John. Telemedicine for Depression in Older People Living with HIV. Acta Psychopathologica. 2017; 3(3):doi.
  4. John MD, Greene M, Hessol NA, Zepf R, Parrott AH, Foreman C, Bourgeois J, Gandhi M, Hare CB. Geriatric Assessments and Association With VACS Index Among HIV-Infected Older Adults in San Francisco. J Acquir Immune Defic Syndr. 2016 Aug 15; 72(5):534-41.
  5. Shiboski CH, Lee A, Chen H, Webster-Cyriaque J, Seaman T, Landovitz RJ, John M, Reilly N, Naini L, Palefsky J, Jacobson MA. Human papillomavirus infection in the oral cavity of HIV patients is not reduced by initiating antiretroviral therapy. AIDS. 2016 06 19; 30(10):1573-82.
  6. John M. The clinical implications of HIV infection and aging. Oral Dis. 2016 Apr; 22 Suppl 1:79-86.
  7. Moyes DL, Saxena D, John MD, Malamud D. The gut and oral microbiome in HIV disease: a workshop report. Oral Dis. 2016 Apr; 22 Suppl 1:166-70.
  8. Jessica Rhee, BA; Eric Chan, MD; Paul Elizondo, III, DO; James Bourgeois, OD, MD; Cameron Foreman, BA; Lisa Dazols, LCSW; Jorien Breur, MD; Joseph Shemuel, BA; Amanda Martin, MSW; Sharonya Shrivastava, BA; Malcolm John, MD, MPH. The Use of Home-Based Telepsychiatry for Mild to Moderate Major Depression in HIV-Positive Adults 50 Years and Older Living in San Francisco. Open Forum Infectious Diseases. 2015; 2(suppl_1):1.
  9. Saberi P, Yuan P, John M, Sheon N, Johnson MO. A pilot study to engage and counsel HIV-positive African American youth via telehealth technology. AIDS Patient Care STDS. 2013 Sep; 27(9):529-32.
  10. Summary report from the Human Immunodeficiency Virus and Aging Consensus Project: treatment strategies for clinicians managing older individuals with the human immunodeficiency virus. J Am Geriatr Soc. 2012 May; 60(5):974-9.
  11. Clark T, Marquez C, Hare CB, John MD, Klausner JD. Methamphetamine use, transmission risk behavior and internet use among HIV-infected patients in medical care, San Francisco, 2008. AIDS Behav. 2012 Feb; 16(2):396-403.
  12. Lao CK, Gruta C, John MD, Cocohoba J. A comparison of tenofovir-associated renal function changes in HIV-infected African Americans vs Caucasians. J Natl Med Assoc. 2011 Jun; 103(6):518-22.
  13. Marquez C, Mitchell SJ, Hare CB, John M, Klausner JD. Methamphetamine use, sexual activity, patient-provider communication, and medication adherence among HIV-infected patients in care, San Francisco 2004-2006. AIDS Care. 2009 May; 21(5):575-82.
  14. Robinson CA, Cocohoba J, MacDougall C, John MD, Guglielmo BJ. Discordance between ambulatory care clinic and community pharmacy medication databases for HIV-positive patients. J Am Pharm Assoc (2003). 2007 Sep-Oct; 47(5):613-5.
  15. John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB. Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death. Clin Infect Dis. 1998 Jun; 26(6):1302-9.
  16. Van Lint C, Amella CA, Emiliani S, John M, Jie T, Verdin E. Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity. J Virol. 1997 Aug; 71(8):6113-27.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.