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Mickie Cheng, M.D.


Dr. Mickie Cheng is an endocrinologist with an interest in endocrine autoimmune diseases. Cheng practices in the UCSF Diabetes Clinic, where she treats patients with both type 1 and type 2 diabetes.

As a member of the UCSF Diabetes Center, Cheng is involved in basic reasearch on a wide range of endocrine autoimmune disorders. Her work focuses on mechanisms of loss of immune tolerance, with emphasis on a translational approach that includes human studies. With a background in reproductive biology, she also has a particular interest in the study of ovarian autoimmune disease.

Cheng completed her undergraduate degree at Princeton University. She received her medical and doctoral degrees from the University of Texas Southwestern Medical Center in Dallas, Texas, where she also completed her residency in internal medicine. She then came to UCSF for a fellowship in endocrinology, diabetes and metabolism. In 2008, she was appointed an adjunct assistant professor in the UCSF School of Medicine.


Diabetes Clinic at Parnassus
400 Parnassus Ave., Suite A-550
San Francisco, CA 94143
Phone: (415) 353–2350
Fax: (415) 353–2337

Hours: Monday to Friday, 8:30 a.m. – 5 pm.

Endocrinology Clinic at Parnassus
400 Parnassus Ave., Suite A-550
San Francisco, CA 94143
Phone: (415) 353–2350
Fax: (415) 353–2337

Hours: Monday to Friday, 8:30 a.m. – 5 pm.

Conditions & Treatments

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University of Texas Southwestern School of Medicine 2002


University of Texas Southwestern Medical Center, Internal Medicine 2004


UCSF Medical Center, Endocrinology 2008

Selected Research and Publications

  1. Bluestone JA, Bour-Jordan H, Cheng M, Anderson M. T cells in the control of organ-specific autoimmunity. J Clin Invest. 2015 Jun 1; 125(6):2250-60.
  2. Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015 Jun; 47(6):654-60.
  3. Price JV, Haddon DJ, Kemmer D, Delepine G, Mandelbaum G, Jarrell JA, Gupta R, Balboni I, Chakravarty EF, Sokolove J, Shum AK, Anderson MS, Cheng MH, Robinson WH, Browne SK, Holland SM, Baechler EC, Utz PJ. Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus. J Clin Invest. 2013 Dec 2; 123(12):5135-45.
  4. Shum AK, Alimohammadi M, Tan CL, Cheng MH, Metzger TC, Law CS, Lwin W, Perheentupa J, Bour-Jordan H, Carel JC, Husebye ES, De Luca F, Janson C, Sargur R, Dubois N, Kajosaari M, Wolters PJ, Chapman HA, Kämpe O, Anderson MS. BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Sci Transl Med. 2013 Oct 9; 5(206):206ra139.
  5. Cheng MH, Anderson MS. Insights into type 1 diabetes from the autoimmune polyendocrine syndromes. Curr Opin Endocrinol Diabetes Obes. 2013 Aug; 20(4):271-8.
  6. Cheng MH, Anderson MS. Monogenic autoimmunity. Annu Rev Immunol. 2012; 30:393-427.
  7. Cheng MH, Nelson LM. Mechanisms and models of immune tolerance breakdown in the ovary. Semin Reprod Med. 2011 Jul; 29(4):308-16.
  8. Otsuka N, Tong ZB, Vanevski K, Tu W, Cheng MH, Nelson LM. Autoimmune oophoritis with multiple molecular targets mitigated by transgenic expression of mater. Endocrinology. 2011 Jun; 152(6):2465-73.
  9. Cheng MH, Fan U, Grewal N, Barnes M, Mehta A, Taylor S, Husebye ES, Murphy EJ, Anderson MS. Acquired autoimmune polyglandular syndrome, thymoma, and an AIRE defect. N Engl J Med. 2010 Feb 25; 362(8):764-6.
  10. Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M, Shum A, Zamir E, Badolato R, Law A, Eisenbarth GS, Anderson MS. A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol. 2007 Nov; 125(2):131-7.
  11. Cheng MH, Shum AK, Anderson MS. What's new in the Aire? Trends Immunol. 2007 Jul; 28(7):321-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.