Paul S. Larson


Neuromodulation surgeon, researcher and amateur chef

About me

Dr. Paul S. Larson is a neurosurgeon who specializes in the surgical treatment of movement disorders, including Parkinson's disease and essential tremor. He is chief of neurosurgery and director of the Center for Advanced Neurosurgical Operative Procedures at the San Francisco Veterans Affairs Health Care System.

Larson's research interests include the use of interventional MRI in deep brain stimulation surgery, the use of gene therapy to treat Parkinson's disease and the role of the basal ganglia (a specific group of neuron clusters in the brain) in hearing.

Larson earned his medical degree at the University of Arizona College of Medicine and completed a residency at the University of Louisville.

Larson has received two teaching awards at UCSF. He has also authored numerous articles and edited two textbooks on functional neurosurgery.

  • Education

    University of Arizona Medical School, 1995

  • Residencies

    University of Louisville, School of Medicine, Neurological Surgery, 2001

  • Fellowships

    University of Louisville, Surgery, 1996

  • Board Certifications

    Neurological Surgery, American Board of Neurological Surgery

  • Academic Title


I feel very fortunate to be part of a team that can have a real impact on each patient's quality of life.

Movement Disorder and Neuromodulation Center

1635 Divisadero St., Suite 520
San Francisco, CA 94115

My reviews


Overall Experience
44 Reviews
My interaction with Dr. Larson was phenomenally good among the best I've ever had with a physician. I would rate him an "excellent" on all counts if that were one of the choices available. He was willing to explain in detail all of the complicated pros and cons of the DBS procedures.
Explained things in a way that was easy to understand
44 Reviews
Did the doctor pay attention to your concerns
44 Reviews
Gave easy to understand instructions about taking care of health problems or concerns
43 Reviews
Knew the important information about your medical history
44 Reviews
The provider showed respect for what you had to say
44 Reviews
The provider spent enough time with me
43 Reviews
Decorative Caduceus

GDNF Gene Therapy for Parkinson's Disease

Evaluation of the safety and tolerability through the assessment of incidence of TEAE, identified by MedDRA preferred term and grouped by MedDRA System Organ Class, as well as clinically meaningful changes in clinical exams or lab...