Randall Lee, PhD, MD

Cardiologist and electrophysiologist

Dr. Randall J. Lee graduated from UCLA Medical School in 1984 where he also obtained his doctorate in pharmacology. After completing an internal medicine residency at Harbor-UCLA Medical Center in Torrance, Calif., he completed a cardiology fellowship and postdoctoral fellowship in biochemistry and molecular biology at Stanford University, where he earned a Physician Scientist Award and the Upjohn Young Investigator Award in cardiology. Lee subspecialized in cardiac electrophysiology during his second fellowship at UCSF.

His research focuses on cellular and molecular aspects of cardiac arrhythmias and vascular regeneration. He is investigating the cellular and molecular derangements that occur during cardiac arrhythmias and myocardial infarctions. Lee uses genetic engineering techniques to investigate derangements during cardiac arrhythmias and myocardial infarctions and as possible therapeutic tools. Lee also is interested in cardiac development of the conduction system and the means to alter conduction, which then may be applied to diseased states.

Clinics

Asian Heart and Vascular Center
1600 Divisadero St., Second Floor, Suite C-244
San Francisco, CA 94115
Appointments: (415) 885-3678
Events: (415) 885-3678
Fax: (415) 885-3676

Cardiac Electrophysiology and Arrhythmia Service
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143
Phone: (415) 353-2554
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Cardiovascular Genetics Program
400 Parnassus Avenue, Plaza Level, Room 94
San Francisco, CA 94143
Phone: (415) 353-2873
Fax: (415) 476-5355

Hours: Monday
noon – 4 p.m

Conditions & Treatments

Board Certification

Cardiovascular Disease, American Board of Internal Medicine

Academic Title

Professor

More about Randall Lee

Education

UCLA School of Medicine 1984

Residencies

Harbor-UCLA Medical Center, Internal Medicine 1988

Fellowships

Stanford University Medical Center, Cardiovascular Diseases 1991

Selected Research and Publications

  1. Sanchez JM, Al-Dosari G, Chu S, Beygui R, Deuse T, Badhwar N, Lee RJ. Hybrid and surgical procedures for the treatment of persistent and longstanding persistent atrial fibrillation. Expert Rev Cardiovasc Ther. 2018 Feb; 16(2):91-97.
  2. Geng X, Hwang J, Ye J, Shih H, Coulter B, Naudin C, Jun K, Sievers R, Yeghiazarians Y, Lee RJ, Boyle AJ. Aging is protective against pressure overload cardiomyopathy via adaptive extracellular matrix remodeling. Am J Cardiovasc Dis. 2017; 7(3):72-82.
  3. Nguyen KT, Gladstone RA, Dukes JW, Nazer B, Vittinghoff E, Badhwar N, Vedantham V, Gerstenfeld EP, Lee BK, Lee RJ, Tseng ZH, Olgin JE, Scheinman MM, Marcus GM. The QT Interval as a Noninvasive Marker of Atrial Refractoriness. Pacing Clin Electrophysiol. 2016 Dec; 39(12):1366-1372.
  4. Badhwar N, Mittal S, Rasekh A, Vasaiwala S, Musat D, S Naeini P, Fang Q, Nentwich K, Deneke T, Chang J, Lakkireddy D, Wilber D, Lee RJ. Conversion of persistent atrial fibrillation to sinus rhythm after LAA ligation with the LARIAT device. Int J Cardiol. 2016 Dec 15; 225:120-122.
  5. Janaswamy P, Walters TE, Nazer B, Lee RJ. Current Treatment Strategies for Heart Failure: Role of Device Therapy and LV Reconstruction. Curr Treat Options Cardiovasc Med. 2016 Sep; 18(9):57.
  6. Lee RJ. Clinical Significance of Leaks Following Left Atrial Appendage Ligation With the LARIAT Suture Delivery Device. JACC Cardiovasc Interv. 2016 05 23; 9(10):1058-60.
  7. Bartus K, Gafoor S, Tschopp D, Foran JP, Tilz R, Wong T, Lakkireddy D, Sievert H, Lee RJ. Left atrial appendage ligation with the next generation LARIAT(+) suture delivery device: Early clinical experience. Int J Cardiol. 2016 Jul 15; 215:244-7.
  8. Lakkireddy D, Afzal MR, Lee RJ, Nagaraj H, Tschopp D, Gidney B, Ellis C, Altman E, Lee B, Kar S, Bhadwar N, Sanchez M, Gadiyaram V, Evonich R, Rasekh A, Cheng J, Cuoco F, Chandhok S, Gunda S, Reddy M, Atkins D, Bommana S, Cuculich P, Gibson D, Nath J, Ferrell R, Matthew E, Wilber D. Short and long-term outcomes of percutaneous left atrial appendage suture ligation: Results from a US multicenter evaluation. Heart Rhythm. 2016 05; 13(5):1030-6.
  9. Gunda S, Reddy M, Nath J, Nagaraj H, Atoui M, Rasekh A, Ellis CR, Badhwar N, Lee RJ, DI Biase L, Mansour M, Ruskin JN, Natale A, Earnest M, Lakkireddy DR. Impact of Periprocedural Colchicine on Postprocedural Management in Patients Undergoing a Left Atrial Appendage Ligation Using LARIAT. J Cardiovasc Electrophysiol. 2016 Jan; 27(1):60-4.
  10. Hall PS, Nazer B, Lee RJ. Reversible High-Grade Atrioventricular Block Associated With Cocaine Use. JAMA Intern Med. 2015 Dec; 175(12):1965-7.
  11. Mann DL, Lee RJ, Coats AJ, Neagoe G, Dragomir D, Pusineri E, Piredda M, Bettari L, Kirwan BA, Dowling R, Volterrani M, Solomon SD, Sabbah HN, Hinson A, Anker SD. One-year follow-up results from AUGMENT-HF: a multicentre randomized controlled clinical trial of the efficacy of left ventricular augmentation with Algisyl in the treatment of heart failure. Eur J Heart Fail. 2016 Mar; 18(3):314-25.
  12. Lee RJ, Lakkireddy D, Mittal S, Ellis C, Connor JT, Saville BR, Wilber D. Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design. Am Heart J. 2015 Dec; 170(6):1184-94.
  13. Ito H, Kawamura M, Badhwar N, Vedantham V, Tseng ZH, Lee BK, Lee RJ, Marcus GM, Gerstenfeld EP, Scheinman MM. The Effect of Direct Current Stimulation versus T-Wave Shock on Defibrillation Threshold Testing. Pacing Clin Electrophysiol. 2015 Oct; 38(10):1173-80.
  14. Lee RJ, Hinson A, Bauernschmitt R, Matschke K, Fang Q, Mann DL, Dowling R, Schiller N, Sabbah HN. The feasibility and safety of Algisyl-LVR™ as a method of left ventricular augmentation in patients with dilated cardiomyopathy: initial first in man clinical results. Int J Cardiol. 2015 Nov 15; 199:18-24.
  15. Anker SD, Coats AJ, Cristian G, Dragomir D, Pusineri E, Piredda M, Bettari L, Dowling R, Volterrani M, Kirwan BA, Filippatos G, Mas JL, Danchin N, Solomon SD, Lee RJ, Ahmann F, Hinson A, Sabbah HN, Mann DL. A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with advanced heart failure (AUGMENT-HF trial). Eur Heart J. 2015 Sep 07; 36(34):2297-309.
  16. Le D, Morelli R, Badhwar N, Lee RJ. Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation. Expert Rev Cardiovasc Ther. 2015; 13(8):907-14.
  17. Kawamura M, Scheinman MM, Lee RJ, Badhwar N. Left atrial appendage ligation in patients with atrial fibrillation leads to a decrease in atrial dispersion. J Am Heart Assoc. 2015 May 14; 4(5).
  18. Badhwar N, Lakkireddy D, Kawamura M, Han FT, Iyer SK, Moyers BS, Dewland TA, Woods C, Ferrell R, Nath J, Earnest M, Lee RJ. Sequential Percutaneous LAA Ligation and Pulmonary Vein Isolation in Patients with Persistent AF: Initial Results of a Feasibility Study. J Cardiovasc Electrophysiol. 2015 Jun; 26(6):608-14.
  19. Yu J, Wu YK, Gu Y, Fang Q, Sievers R, Ding CH, Olgin JE, Lee RJ. Immuno-modification of enhancing stem cells targeting for myocardial repair. J Cell Mol Med. 2015 Jul; 19(7):1483-91.
  20. Nguyen J, Sievers R, Motion JP, Kivimäe S, Fang Q, Lee RJ. Delivery of lipid micelles into infarcted myocardium using a lipid-linked matrix metalloproteinase targeting peptide. Mol Pharm. 2015 Apr 06; 12(4):1150-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.