Richard Tsai, MBA, MD


Dr. Richard Tsai is a behavioral neurologist, a specialist in nervous system disorders that affect cognitive functions such as memory, learning, perception and problem solving. He works with a multidisciplinary team to diagnose and treat patients with memory issues or dementia syndromes.

Tsai's research focuses on treatments, biomarkers and clinical trial methodology for neurodegenerative diseases. He is an investigator on many neurodegenerative clinical trials to identify disease modifying treatments for dementia. He is also interested in developing structural and molecular brain imaging techniques to improve the diagnosis and measurement of neurodegenerative disease.

A member of the outreach team for the UCSF Alzheimer's Disease Research Center, Tsai has a special interest in differences in the symptoms and disease processes of memory disorders in Chinese Americans in comparison to white Americans of European origin. Tsai is fluent in Mandarin Chinese, and in addition to his patients at the UCSF Memory and Aging Center, Tsai sees patients at the nonprofit Chinese Hospital and Chinatown Public Health Center.

Tsai earned his bachelor's degree in molecular and cell biology at the University of California, Berkeley, followed by a joint medical degree and master's degree in business administration at Drexel University. He completed a neurology residency at the Albert Einstein College of Medicine and a fellowship in behavioral neurology at UCSF. He is an assistant professor of neurology at UCSF.


Memory and Aging Center
1500 Owens St., Suite 320
San Francisco, CA 94158
Phone: (415) 353-2057
Fax: (415) 353-8292

Hours: Monday to Friday
8 a.m. – 5 p.m.

Academic Title

Assistant Professor

More about Richard Tsai

Additional Languages



UC Berkeley, B.S., Molecular and Cell Biology 2003
Drexel University College of Medicine 2008
LeBow College of Business, M.B.A. 2008


Albert Einstein College of Medicine, Neurology 2013


UCSF, Behavioral Neurology 2015

Selected Research and Publications

  1. Rojas JC, Bang J, Lobach IV, Tsai RM, Rabinovici GD, Miller BL, Boxer AL. CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP. Neurology. 2018 Jan 23; 90(4):e273-e281.
  2. Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 2017 09 28; 549(7673):523-527.
  3. Tsai RM, Boxer AL. Therapy and clinical trials in frontotemporal dementia: past, present, and future. J Neurochem. 2016 Aug; 138 Suppl 1:211-21.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.