Ronald Clyman, MD


Dr. Ronald Clyman is a neonatologist and an expert in the treatment of extremely premature infants. He is internationally renowned for his basic and clinical studies of the ductus arteriousus, a blood vessel that transports blood from the right side of the heart to the aorta, which is the large blood vessel that distributes blood to a baby's body while still in the womb. He has helped define the role of oxygen and prostaglandins in ductus patency and is currently studying the mechanisms leading to irreversible ductal closure. Clyman is a professor of pediatrics at the University of California, San Francisco and a member of the Cardiovascular Research Institute. He earned his medical degree at Columbia University and is board certified in pediatrics and neonatal and perinatal medicine.

More about Ronald Clyman


Columbia University School of Medicine 1971

Selected Research and Publications

  1. Clyman RI, Liebowitz M. Treatment and Nontreatment of the Patent Ductus Arteriosus: Identifying Their Roles in Neonatal Morbidity. J Pediatr. 2017 Oct; 189:13-17.
  2. Goyal R, Clyman RI. Response to Coceani et al. Pediatr Res. 2017 Aug; 82(2):175.
  3. Liebowitz M, Clyman RI. Prophylactic Indomethacin Compared with Delayed Conservative Management of the Patent Ductus Arteriosus in Extremely Preterm Infants: Effects on Neonatal Outcomes. J Pediatr. 2017 Aug; 187:119-126.e1.
  4. Liebowitz M, Koo J, Wickremasinghe A, Allen IE, Clyman RI. Effects of Prophylactic Indomethacin on Vasopressor-Dependent Hypotension in Extremely Preterm Infants. J Pediatr. 2017 Mar; 182:21-27.e2.
  5. Liebowitz M, Clyman RI. Antenatal Betamethasone: A Prolonged Time Interval from Administration to Delivery Is Associated with an Increased Incidence of Severe Intraventricular Hemorrhage in Infants Born before 28 Weeks Gestation. J Pediatr. 2016 Oct; 177:114-120.e1.
  6. Goyal R, Goyal D, Longo LD, Clyman RI. Microarray gene expression analysis in ovine ductus arteriosus during fetal development and birth transition. Pediatr Res. 2016 Oct; 80(4):610-8.
  7. Jelin AC, Zlatnik MG, Kuppermann M, Gregorich SE, Nakagawa S, Clyman R. Clamp late and maintain perfusion (CLAMP) policy: delayed cord clamping in preterm infants. J Matern Fetal Neonatal Med. 2016; 29(11):1705-9.
  8. Waleh N, Barrette AM, Dagle JM, Momany A, Jin C, Hills NK, Shelton EL, Reese J, Clyman RI. Effects of Advancing Gestation and Non-Caucasian Race on Ductus Arteriosus Gene Expression. J Pediatr. 2015 Nov; 167(5):1033-41.e2.
  9. Simon SR, van Zogchel L, Bas-Suárez MP, Cavallaro G, Clyman RI, Villamor E. Platelet Counts and Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis. Neonatology. 2015; 108(2):143-51.
  10. Liebowitz MC, Clyman RI. Predicting the Need for Home Oxygen Therapy in Preterm Infants Born Before 28 Weeks' Gestation. Am J Perinatol. 2016 Jan; 33(1):34-9.
  11. Noori S, McNamara P, Jain A, Lavoie PM, Wickremasinghe A, Merritt TA, Solomon T, Sekar K, Attridge JT, Swanson JR, Gillam-Krakauer M, Reese J, Poindexter BB, Brook M, Auchus RJ, Clyman RI. Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation. J Perinatol. 2015 Feb; 35(2):123-7.
  12. Heuchan AM, Clyman RI. Managing the patent ductus arteriosus: current treatment options. Arch Dis Child Fetal Neonatal Ed. 2014 Sep; 99(5):F431-6.
  13. Clyman RI, Wickremasinghe A, Merritt TA, Solomon T, McNamara P, Jain A, Singh J, Chu A, Noori S, Sekar K, Lavoie PM, Attridge JT, Swanson JR, Gillam-Krakauer M, Reese J, DeMauro S, Poindexter B, Aucott S, Satpute M, Fernandez E, Auchus RJ. Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones. J Pediatr. 2014 Jun; 164(6):1449-55.e1.
  14. Jelin AC, Kuppermann M, Erickson K, Clyman R, Schulkin J. Obstetricians' attitudes and beliefs regarding umbilical cord clamping. J Matern Fetal Neonatal Med. 2014 Sep; 27(14):1457-61.
  15. Yanowitz TD, Reese J, Gillam-Krakauer M, Cochran CM, Jegatheesan P, Lau J, Tran VT, Walsh M, Carey WA, Fujii A, Fabio A, Clyman R. Superior mesenteric artery blood flow velocities following medical treatment of a patent ductus arteriosus. J Pediatr. 2014 Mar; 164(3):661-3.
  16. Clyman RI. The role of patent ductus arteriosus and its treatments in the development of bronchopulmonary dysplasia. Semin Perinatol. 2013 Apr; 37(2):102-7.
  17. Clyman R, Wickremasinghe A, Jhaveri N, Hassinger DC, Attridge JT, Sanocka U, Polin R, Gillam-Krakauer M, Reese J, Mammel M, Couser R, Mulrooney N, Yanowitz TD, Derrick M, Jegatheesan P, Walsh M, Fujii A, Porta N, Carey WA, Swanson JR. Enteral feeding during indomethacin and ibuprofen treatment of a patent ductus arteriosus. J Pediatr. 2013 Aug; 163(2):406-11.
  18. Catenacci M, Miyagi S, Wickremasinghe AC, Lucas SS, de Alba Campomanes AG, Good WV, Clyman RI. Dopamine-resistant hypotension and severe retinopathy of prematurity. J Pediatr. 2013 Aug; 163(2):400-5.
  19. Clyman RI. Surgical ligation of the patent ductus arteriosus: treatment or morbidity? J Pediatr. 2012 Oct; 161(4):583-4.
  20. Wickremasinghe AC, Rogers EE, Piecuch RE, Johnson BC, Golden S, Moon-Grady AJ, Clyman RI. Neurodevelopmental outcomes following two different treatment approaches (early ligation and selective ligation) for patent ductus arteriosus. J Pediatr. 2012 Dec; 161(6):1065-72.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.