William R. Ryan, MD

Otolaryngologist

Dr. William R. Ryan is a head and neck surgeon at the UCSF Helen Diller Family Comprehensive Cancer Center. He is skilled in caring for patients with benign and malignant tumors, as well as salivary gland inflammatory disorders, using endoscopic, minimally invasive and traditional surgical techniques. He regularly performs ultrasonography in clinic and in the operating room for his patients. He also has special expertise in transoral robotic surgery, sialendoscopy, sentinel lymph node biopsy and regional facial reconstruction.

Ryan helps direct the Robotic Head and Neck Surgery program, Thyroid and Parathyroid Surgery Clinic and Salivary Gland Surgery Center at UCSF. He is committed to being as accessible as possible to his patients.

Ryan is actively involved in teaching in the UCSF residency and fellowship training programs and UCSF School of Medicine. He also conducts clinical research on the outcomes and other aspects of head and neck surgery, salivary duct surgery, and head and neck radiology. He has authored more than 50 published medical journal articles and several book chapters and is a regular reviewer for the journals Head & Neck, JAMA Otolaryngology – Head & Neck Surgery, and several others.

Ryan earned his medical degree from Stanford University School of Medicine, where he also completed his residency in otolaryngology-head and neck surgery. He then completed a fellowship in advanced head and neck oncologic and endocrine surgery at UCSF. He joined the UCSF faculty in 2011.

Clinics

Head and Neck Surgery Cancer Clinic
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday
8 a.m. – 5 p.m.

Salivary Gland Surgery Center at Mission Bay
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885-7528
Fax: (415) 885-7711

Hours: Monday to Friday,
8 a.m. – 5 p.m.

Thyroid and Parathyroid Surgery
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885-7528
Fax: (415) 885-7711

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

Board Certification

Otolaryngology, American Board of Otolaryngology

Academic Title

Associate Professor

More about William R. Ryan

Education

Stanford University School of Medicine 2005

Residencies

Stanford University Medical Center 2010

Fellowships

UCSF, Advanced Head and Neck Oncologic Surgery 2011

Selected Research and Publications

  1. Yin LX, D'Souza G, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig EM, Ryan WR, Ha PK, Wentz A, Koch W, Eisele DW, Fakhry C. Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas. Laryngoscope. 2018 Mar 14.
  2. Xu MJ, Lazar AA, Garsa AA, Arron ST, Ryan WR, El-Sayed IH, George JR, Algazi AP, Heaton CM, Ha PK, Yom SS. Major prognostic factors for recurrence and survival independent of the American Joint Committee on Cancer eighth edition staging system in patients with cutaneous squamous cell carcinoma treated with multimodality therapy. Head Neck. 2018 Mar 10.
  3. Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH. High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells. Stem Cell Reports. 2018 Mar 13; 10(3):1160-1174.
  4. Alonso JE, Han AY, Kuan EC, Strohl M, Clair JM, St John MA, Ryan WR, Heaton CM. The survival impact of surgical therapy in squamous cell carcinoma of the hard palate. Laryngoscope. 2018 Feb 05.
  5. Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 Jan 15.
  6. Zhou MJ, van Zante A, Lazar AA, Groppo ER, Garsa AA, Ryan WR, El-Sayed IH, Eisele DW, Yom SS. Squamous cell carcinoma of unknown primary of the head and neck: Favorable prognostic factors comparable to those in oropharyngeal cancer. Head Neck. 2017 Dec 06.
  7. Togarrati PP, Dinglasan N, Desai S, Ryan WR, Muench MO. CD29 is highly expressed on epithelial, myoepithelial, and mesenchymal stromal cells of human salivary glands. Oral Dis. 2017 Dec 02.
  8. Tamplen ML, Tamplen J, Shuman E, Heaton CM, George JR, Wang SJ, Ryan WR. Comparison of Output Volume Thresholds for Drain Removal After Selective Lateral Neck Dissection: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2017 Dec 01; 143(12):1195-1199.
  9. Strohl MP, Dewyer NA, Sckolnick J, Ryan WR. A Novel Approach to Oropharyngeal Foreign Body Removal. Otolaryngol Head Neck Surg. 2018 Jan; 158(1):194-196.
  10. Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR. Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes. Otolaryngol Head Neck Surg. 2017 Dec; 157(6):973-980.
  11. Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR. Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 Dec; 127(12):2770-2776.
  12. Naunheim M, Wu X, Ryan WR, Wang SJ, Heaton CM. Volumetric Growth Rate of Recurrent Pleomorphic Adenoma. Ann Otol Rhinol Laryngol. 2017 Jul; 126(7):544-547.
  13. Togarrati PP, Sasaki RT, Abdel-Mohsen M, Dinglasan N, Deng X, Desai S, Emmerson E, Yee E, Ryan WR, da Silva MCP, Knox SM, Pillai SK, Muench MO. Identification and characterization of a rich population of CD34+ mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. Sci Rep. 2017 Jun 14; 7(1):3484.
  14. Markey JD, Morrel WG, Wang SJ, Ryan WR. The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia. Auris Nasus Larynx. 2018 Feb; 45(1):123-127.
  15. Ghosh P, Lazar AA, Ryan WR, Yom SS. A feasibility and efficacy trial of a hand-held humidification device in patients undergoing radiotherapy for head and neck cancer. Support Care Cancer. 2017 08; 25(8):2611-2618.
  16. Fakhry C, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig E, Yin LX, Ryan WR, Ha PK, Wentz A, Koch W, Richmon JD, Eisele DW, D'Souza G. The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer. Cancer. 2017 05 01; 123(9):1566-1575.
  17. Tamplen ML, Tamplen J, Torrecillas V, Seth R, Ricceri S, Hemmat S, Heaton C, Ryan WR, Knott PD. Does a Standalone Cancer Center Improve Head and Neck Microsurgical Outcomes? J Reconstr Microsurg. 2017 May; 33(4):252-256.
  18. Heaton CM, Ahmed SR, Ryan WR. Transoral robotic surgery (TORS) for excision of a retropharyngeal intramuscular lipoma. Auris Nasus Larynx. 2017 Dec; 44(6):742-744.
  19. D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C. Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method. JAMA Oncol. 2016 Dec 08.
  20. JŠuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL. Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings. Laryngoscope. 2017 Jul; 127(7):1565-1570.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.