Ectodermal Dysplasia

Signs and Symptoms

Ectodermal dysplasia is a disorder involving two or more of the ectodermal structures, which include the skin, hair, nails, teeth, mucous membranes and sweat glands. How an individual is affected varies. For example, in one individual the hair and nails may be affected, while in another the disorder may involve the sweat glands and teeth. Each combination is considered a distinct type of ectodermal dysplasia.

Diagnosis

Ectodermal dysplasia is diagnosed by physical exam. Although present at birth, milder forms of the disorder may go undetected until symptoms begin to affect a child's daily life or development. A genetic evaluation helps to determine if the condition is isolated, hereditary or occurring as part of another syndrome or condition.

Ectodermal dysplasia should be diagnosed and treated by an experienced team of experts recognized by the American Cleft Palate-Craniofacial Association, like the Center for Craniofacial Anomalies at UCSF.

Treatment

A special ectodermal dysplasia clinic is held at the Center for Craniofacial Anomalies at UCSF several times a year. This clinic includes our regular team of specialists plus a dermatologist and a prosthodontist. This group of experts considers the special needs of each patient as they develop a treatment plan, which may include:

• Recommendations for dentures or implants
• Special treatment for hair, nails and skin
• Recommendations for lifestyle adjustments to maximize comfort and health

Treatment necessary to address symptoms of ectodermal dysplasia, including dentures and implants, is considered reconstructive and not cosmetic.

A child with ectodermal dysplasia may encounter social and emotional challenges unique to this condition. Support organizations and resources are available for children and their families.