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Chris Freise, M.D.

Transplant surgeon

Dr. Christopher E. Freise is a member of the UCSF Transplant Service with particular interest in adult and pediatric liver and kidney transplants, surgery for liver tumors and kidney cysts, laparoscopic surgery for the liver and gall bladder, and surgery for dialysis access. In his research, he addresses immunosuppressive drugs used after transplantation and methods to prevent ischema-reperfusion injury or tissue damage after blood supply is restored. His research is recognized and funded by the National Institutes of Health and the American Society of Transplant Surgeons.

Freise earned a medical degree at the University of Minnesota, where he completed a residency in surgery. He completed a postdoctoral fellowship in transplant surgery at UCSF Medical Center. He is certified by the American Board of Surgery and is a fellow of the American College of Surgeons.


Connie Frank Transplant Center at UCSF
400 Parnassus Ave., Seventh Floor
San Francisco, CA 94143
Phone: (415) 353-1551
Pre-Kidney Fax: (415) 353-8708
Post-Kidney Fax: (415) 353-8381

Hours: 8 a.m. – 5 p.m.

Liver Transplant Program
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143
Phone: (415) 353-1888
Fax: (415) 353-8917

Hours: Pre-Liver Transplant Clinic Monday, Tuesday 7 a.m. – 12 p.m.
Hours: Post-Liver Transplant Clinic Tuesday 8 a.m. – 12 p.m.

Pancreas Transplant Services
400 Parnassus Ave., Seventh Floor
San Francisco, CA 94143
Phone: (415) 353-1551
Pre-Transplant Fax: (415) 353-8708
Post-Transplant Fax: (415) 353-4183

Hours: Monday to Friday
8 a.m. – 5 p.m.

Polycystic Kidney Disease (PKD) Center of Excellence
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143
Phone: (415) 514-2381

Hours: Monday to Friday,
9 a.m. - 5 p.m.

Conditions & Treatments

More about Chris Freise

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University of Minnesota School of Medicine 1986


University of Minnesota Medical Center, General Surgery 1994


UCSF Medical Center, Surgery 1996

Selected Research and Publications

  1. Olthoff KM, Smith AR, Abecassis M, Baker T, Emond JC, Berg CL, Beil CA, Burton JR, Fisher RA, Freise CE, Gillespie BW, Grant DR, Humar A, Kam I, Merion RM, Pomfret EA, Samstein B, Shaked A. Defining Long-term Outcomes With Living Donor Liver Transplantation in North America. Ann Surg. 2015 Sep; 262(3):465-75.
  2. Freise C, Kim KY, Querfeld U. A Lindera obtusiloba Extract Blocks Calcium-/Phosphate-Induced Transdifferentiation and Calcification of Vascular Smooth Muscle Cells and Interferes with Matrix Metalloproteinase-2 and Metalloproteinase-9 and NF-?B. Evid Based Complement Alternat Med. 2015; 2015:679238.
  3. Tran G, Ramaswamy K, Chi T, Meng M, Freise C, Stoller ML. Laparoscopic Nephrectomy with Autotransplantation: Safety, Efficacy and Long-Term Durability. J Urol. 2015 Sep; 194(3):738-43.
  4. Olthoff KM, Emond JC, Shearon TH, Everson G, Baker TB, Fisher RA, Freise CE, Gillespie BW, Everhart JE. Liver regeneration after living donor transplantation: Adult-to-adult living donor liver transplantation cohort study. Liver Transpl. 2015 Jan; 21(1):79-88.
  5. Ladner DP, Dew MA, Forney S, Gillespie BW, Brown RS, Merion RM, Freise CE, Hayashi PH, Hong JC, Ashworth A, Berg CL, Burton JR, Shaked A, Butt Z. Long-term quality of life after liver donation in the adult to adult living donor liver transplantation cohort study (A2ALL). J Hepatol. 2015 Feb; 62(2):346-53.
  6. Flemming JA, Vagefi PA, Freise CE, Yao FY, Terrault NA. Restricting liver transplant recipients to younger donors does not increase the wait-list time or the dropout rate: the hepatitis C experience. Liver Transpl. 2014 Oct; 20(10):1202-10.
  7. Luu HY, Ulloa JG, Roll GR, Freise CE. Emesis following laparoscopic left donor nephrectomy. Am J Transplant. 2014 Jul; 14(7):1701; quiz 1700, 1702.
  8. Freise C, Querfeld U. Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34. Pharmacol Res. 2014 Jul; 85:6-14.
  9. Campsen J, Zimmerman M, Trotter J, Hong J, Freise C, Brown RS, Cameron A, Ghobrial M, Kam I, Busuttil R, Saab S, Holt C, Emond JC, Stiles JB, Lukose T, Chang MS, Klintmalm G. Multicenter review of liver transplant for hepatitis B-related liver disease: disparities in gender and ethnicity. Clin Transplant. 2013 Nov-Dec; 27(6):829-37.
  10. Campsen J, Zimmerman M, Trotter J, Hong J, Freise C, Brown R, Cameron A, Ghobrial M, Kam I, Busuttil R, Saab S, Holt C, Emond J, Stiles J, Lukose T, Chang M, Klintmalm G. Liver transplantation for hepatitis B liver disease and concomitant hepatocellular carcinoma in the United States With hepatitis B immunoglobulin and nucleoside/nucleotide analogues. Liver Transpl. 2013 Sep; 19(9):1020-9.
  11. Vagefi PA, Parekh J, Ascher NL, Roberts JP, Freise CE. Ex vivo split-liver transplantation: the true right/left split. HPB (Oxford). 2014 Mar; 16(3):267-74.
  12. Zimmerman MA, Baker T, Goodrich NP, Freise C, Hong JC, Kumer S, Abt P, Cotterell AH, Samstein B, Everhart JE, Merion RM. Development, management, and resolution of biliary complications after living and deceased donor liver transplantation: a report from the adult-to-adult living donor liver transplantation cohort study consortium. Liver Transpl. 2013 Mar; 19(3):259-67.
  13. Hobeika M, Pollitt R, Freise C, Shinkai K. Fever and rash one month after orthotopic liver transplantation. Am J Transplant. 2013 Jan; 13(1):236-8; quiz 238.
  14. Kulik LM, Fisher RA, Rodrigo DR, Brown RS, Freise CE, Shaked A, Everhart JE, Everson GT, Hong JC, Hayashi PH, Berg CL, Lok AS. Outcomes of living and deceased donor liver transplant recipients with hepatocellular carcinoma: results of the A2ALL cohort. Am J Transplant. 2012 Nov; 12(11):2997-3007.
  15. Park SJ, Freise CE, Hirose R, Kerlan RK, Yao FY, Roberts JP, Vagefi PA. Risk factors for liver transplant waitlist dropout in patients with hepatocellular carcinoma. Clin Transplant. 2012 Jul-Aug; 26(4):E359-64.
  16. Abecassis MM, Fisher RA, Olthoff KM, Freise CE, Rodrigo DR, Samstein B, Kam I, Merion RM. Complications of living donor hepatic lobectomy--a comprehensive report. Am J Transplant. 2012 May; 12(5):1208-17.
  17. Vagefi PA, Ascher NL, Freise CE, Dodge JL, Roberts JP. Use of living donor liver transplantation varies with the availability of deceased donor liver transplantation. Liver Transpl. 2012 Feb; 18(2):160-5.
  18. Vagefi PA, Parekh J, Ascher NL, Roberts JP, Freise CE. Outcomes with split liver transplantation in 106 recipients: the University of California, San Francisco, experience from 1993 to 2010. Arch Surg. 2011 Sep; 146(9):1052-9.
  19. Vagefi PA, Eilers H, Hiniker A, Freise CE. Liver transplantation for giant hepatic angiomyolipoma. Liver Transpl. 2011 Aug; 17(8):985-6.
  20. Ahearn AJ, Posselt AM, Kang SM, Roberts JP, Freise CE. Experience with laparoscopic donor nephrectomy among more than 1000 cases: low complication rates, despite more challenging cases. Arch Surg. 2011 Jul; 146(7):859-64.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.