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Tom Lue, M.D.


Dr. Tom Lue is an internationally recognized expert in the treatment of male sexual dysfunction at UCSF Medical Center. In 1983, he was one of the first urologists in the country to offer penile injection for erectile dysfunction. His research team proved that a new class of compound enhances erection in animals, which provided the scientific basis for three medications — Viagra, Levitra and Cialis, the most popular treatments for erectile dysfunction. Lue and his associates also developed the first animal model to study Peyronie's disease and introduced pentoxifylline for treatment.

Lue is vice chair of urology, medical director of the Knuppe Molecular Urology Laboratory and a professor of urology at UCSF. He graduated with highest honors from the Kaohsiung Medical College in Taiwan, completed urologic training at Downstate Medical Center in Brooklyn, N.Y. and was awarded the Valentine Fellowship from the New York Academy of Medicine to study the neurophysiology of the genitourinary tract at UCSF. He has won numerous awards, including the American Urological Association's Gold Cystoscope award and American Foundation of Urologic Disease's "Most Innovative Research Award." Lue has authored or co-authored more than 380 publications and 12 books on male sexual dysfunction.


Urology Practice
400 Parnassus Ave., Sixth Floor, Suite A610
San Francisco, CA 94143
Phone: (415) 353-2200
Fax: (415) 353-2641

Hours: Monday to Friday
8 a.m. – 5 p.m.

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Kaohsiung Medical College 1972


SUNY Downstate Medical Center, Urology 1981


UCSF Medical Center, Urology

Selected Research and Publications

  1. Wang L, Zhang X, Wang G, Visweswariah SS, Lin G, Xin Z, Lue TF, Lin CS. Lobe-specific Expression of Phosphodiesterase 5 in Rat Prostate. Urology. 2015 Mar; 85(3):703.e7-703.e13.
  2. Alwaal A, Wang L, Zaid UB, Lin G, Lue TF. Case series of lipid accumulation in the human corpus cavernosum. Medicine (Baltimore). 2015 Feb; 94(6):e550.
  3. Zaid UB, Alwaal A, Zhang X, Lue TF. Surgical Management of Peyronie's Disease. Curr Urol Rep. 2014 Oct; 15(10):446.
  4. Wang J, Huang V, Ye L, Bárcena A, Lin G, Lue TF, Li LC. Identification of Small Activating RNAs that Enhance Endogenous OCT4 Expression in Human Mesenchymal Stem Cells. Stem Cells Dev. 2014 Sep 18.
  5. Ning H, Lei HE, Xu YD, Guan RL, Venstrom JM, Lin G, Lue TF, Xin Z, Lin CS. Conversion of adipose-derived stem cells into natural killer-like cells with anti-tumor activities in nude mice. PLoS One. 2014; 9(8):e106246.
  6. Lin G, Alwaal A, Zhang X, Wang J, Wang L, Lin H, Wang G, Ning H, Lin CS, Xin Z, Lue TF. Presence of Stem/Progenitor Cells in The Rat Penis. Stem Cells Dev. 2014 Aug 27.
  7. Ferretti L, Fandel TM, Qiu X, Zhang H, Orabi H, Wu AK, Banie L, Wang G, Lin G, Lin CS, Lue TF. Tunica albuginea allograft: a new model of LaPeyronie's disease with penile curvature and subtunical ossification. Asian J Androl. 2014 Jul-Aug; 16(4):592-6.
  8. Li X, Fang D, Cooperberg MR, Whitson JM, Lue TF, Zhou L, Shinohara K. Long-term follow-up of International Prostate Symptom Score (IPSS) in men following prostate brachytherapy. World J Urol. 2014 Aug; 32(4):1061-6.
  9. Lin CS, Xin Z, Dai J, Huang YC, Lue TF. Stem-cell therapy for erectile dysfunction. Expert Opin Biol Ther. 2013 Nov; 13(11):1585-97.
  10. Albersen M, Berkers J, Dekoninck P, Deprest J, Lue TF, Hedlund P, Lin CS, Bivalacqua TJ, Van Poppel H, De Ridder D, Van der Aa F. Expression of a Distinct Set of Chemokine Receptors in Adipose Tissue-Derived Stem Cells is Responsible for In Vitro Migration Toward Chemokines Appearing in the Major Pelvic Ganglion Following Cavernous Nerve Injury. Sex Med. 2013 Aug; 1(1):3-15.
  11. Song WD, Yuan YM, Cui WS, Wu AK, Zhu YC, Liu J, Wang L, Bai GY, Peng J, Zhang ZC, Gao B, Guo YL, Lue TF, Xin ZC. Penile prosthesis implantation in Chinese patients with severe erectile dysfunction: 10-year experience. Asian J Androl. 2013 Sep; 15(5):658-61.
  12. Lin CS, Xin ZC, Dai J, Lue TF. Commonly used mesenchymal stem cell markers and tracking labels: Limitations and challenges. Histol Histopathol. 2013 Sep; 28(9):1109-16.
  13. Hakky TS, Ferguson D, Spiess PE, Bradley P, Lue TF, Carrion RE. Three-dimensional mapping and comparative analysis of the distal human corpus cavernosum and the inflatable penile prosthesis. Asian J Androl. 2013 Jul; 15(4):567-70.
  14. Khurana A, Nejadnik H, Chapelin F, Lenkov O, Gawande R, Lee S, Gupta SN, Aflakian N, Derugin N, Messing S, Lin G, Lue TF, Pisani L, Daldrup-Link HE. Ferumoxytol: a new, clinically applicable label for stem-cell tracking in arthritic joints with MRI. Nanomedicine (Lond). 2013 Dec; 8(12):1969-83.
  15. Lin CS, Xin Z, Namiki M, Albersen M, Muller D, Lue TF. Direct androgen regulation of PDE5 gene or the lack thereof. Int J Impot Res. 2013 May; 25(3):81-5.
  16. Lin CS, Lue TF. Words of wisdom: re: characterization of the early proliferative response of the rodent bladder to subtotal cystectomy: a unique model of mammalian organ regeneration. Eur Urol. 2013 Feb; 63(2):401-2.
  17. Walsh TJ, Hotaling JM, Lue TF, Smith JF. How curved is too curved? The severity of penile deformity may predict sexual disability among men with Peyronie's disease. Int J Impot Res. 2013 May; 25(3):109-12.
  18. Lin CS, Lue TF. Defining vascular stem cells. Stem Cells Dev. 2013 Apr 1; 22(7):1018-26.
  19. Lin CS, Albersen M, Xin Z, Namiki M, Muller D, Lue TF. Phosphodiesterase-5 expression and function in the lower urinary tract: a critical review. Urology. 2013 Mar; 81(3):480-7.
  20. Ning H, Albersen M, Lin G, Lue TF, Lin CS. Effects of EdU labeling on mesenchymal stem cells. Cytotherapy. 2013 Jan; 15(1):57-63.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.