Total Pancreatectomy – Islet Auto-Transplant (TP-IAT)
On this page
Get care
Why choose UCSF Health for total pancreatectomy – islet auto-transplantation (TP-IAT)?
At UCSF Health, we offer total pancreatectomy with islet auto-transplantation (TP-IAT) to help people living with chronic or recurrent acute pancreatitis. This advanced procedure removes your pancreas to relieve severe pain while helping preserve your ability to make insulin.
TP-IAT lowers your chances of developing surgically induced diabetes. We are among the only programs in the western U.S. providing this innovative treatment.
The majority of our patients experience significant pain relief after TP-IAT, and many no longer need insulin or pain medication. We are committed to delivering safe, effective transplant care with leading-edge expertise.
Why choose UCSF Health for total pancreatectomy – islet auto-transplantation (TP-IAT)?
At UCSF Health, we offer total pancreatectomy with islet auto-transplantation (TP-IAT) to help people living with chronic or recurrent acute pancreatitis. This advanced procedure removes your pancreas to relieve severe pain while helping preserve your ability to make insulin.
TP-IAT lowers your chances of developing surgically induced diabetes. We are among the only programs in the western U.S. providing this innovative treatment.
The majority of our patients experience significant pain relief after TP-IAT, and many no longer need insulin or pain medication. We are committed to delivering safe, effective transplant care with leading-edge expertise.
Get care
Skilled surgical team
TP-IAT requires expertise found at only a few programs worldwide. Our experienced team performs these procedures safely and effectively.Improved survival rates
Our patients have excellent survival rates following TP-IAT.No risk of rejection
Using your cells instead of donor cells eliminates the risk of rejection. You don't have to take anti-rejection medications after surgery.Pain reduction for improved quality of life
After TP-IAT, more than 90% of our patients can substantially reduce pain medication use.
World leaders in unique procedure for pancreatitis
Pancreatitis is a painful condition that can severely affect your quality of life. Traditionally, the treatment for severe pancreatitis was pancreas removal. However, this procedure causes patients to develop diabetes, requiring insulin injections for life.
TP-IAT relieves pancreas pain while allowing your care team to preserve your insulin-producing islet cells and reinject them. These cells enable your body to continue making insulin, lowering your chances for diabetes. Unlike transplants with donor cells and organs, there's no risk of rejection.
Our outcomes are consistently better than those of other top hospitals performing TP-IAT:
More than 90% of our patients can significantly reduce pain medication following TP-IAT.
More than 50% of our patients can stop taking pain medication following TP-IAT.
At UCSF Health, you benefit from our decades of transplant expertise. You also have access to specialists across our entire system.
Providers
Andrew Posselt, MD, PhD
Gastrointestinal Surgery • Pancreas Transplant Surgery
Umesh Masharani, MD
Diabetes • Diabetes Education
Nationally recognized for our excellent care
Best in Northern California for gastroenterology & GI surgery
Related services
Related conditions & treatments
Conditions
Treatments
Accreditations & memberships
Member Collaborative Islet Transplant RegistryOpens in a new window
This organization promotes the safety of islet transplantation by collecting and analyzing worldwide data.Member Clinical Islet Transplantation ConsortiumOpens in a new window
The National Institutes of Health (NIH) sponsors this multi-center research organization.
Support services
Case Management and Social Work
Connect with a team that can help you find resources, solve problems and advocate for you during treatment at UCSF.
Mindfulness-Based Stress Reduction Class
This eight-week class teaches mindfulness practices that can reduce stress and improve your overall health, such as meditation and body awareness.
Patient Relations
We welcome feedback about your experience at UCSF Health. Find out how to contact us with comments, questions or concerns.
Spiritual Care at UCSF
Chaplains representing many faiths are available around the clock to provide support, comfort and counsel to patients, families and caregivers.