Fibrin degradation products blood test
Fibrin degradation products (FDPs) are the substances left behind when clots dissolve in the blood. A blood test can be done to measure these products.
FDPs; FSPs; Fibrin split products; Fibrin breakdown products
How the Test is Performed
How to Prepare for the Test
Certain medicines can change blood test results.
- Tell your health care provider about all the medicines you take.
- Your provider will tell you if you need to temporarily stop taking any medicines before you have this test. This includes blood thinners such as aspirin, heparin, streptokinase, and urokinase, which make it hard for the blood to clot.
- Do not stop or change your medicines without talking to your provider first.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.
Why the Test is Performed
This test is done to see if your clot-dissolving (fibrinolytic) system is working properly. Your provider may order this test if you have signs of
The result is normally less than 10 mcg/mL (10 mg/L).
Note: Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results.
What Abnormal Results Mean
Increased FDPs may be a sign of primary or secondary fibrinolysis (clot-dissolving activity) due to a variety of causes, including:
- Blood clotting problems
- Problem with the heart's structure and function that is present at birth (
congenital heart disease)
- Disseminated intravascular coagulation (DIC)
- Low level of oxygen in the blood
- Problem during pregnancy such as preeclampsia,
placenta abruptio, miscarriage
- Recent blood transfusion
- Recent surgery that involved a heart and lung bypass pump, or surgery to lower high blood pressure in the liver
- Kidney disease
Transplant rejection Transfusion reaction
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks with having blood drawn are slight, but may include:
- Excessive bleeding
- Fainting or feeling lightheaded
- Multiple punctures to locate veins
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
Chernecky CC, Berger BJ. Fibrinogen breakdown products (fibrin degradation products, FDP) - blood. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:525-526.
Levi M. Disseminated intravascular coagulation. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 139.
Review Date: 01/29/2019
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright ©2019 A.D.A.M., Inc., as modified by University of California San Francisco. Any duplication or distribution of the information contained herein is strictly prohibited.
Information developed by A.D.A.M., Inc. regarding tests and test results may not directly correspond with information provided by UCSF Health. Please discuss with your doctor any questions or concerns you may have.