Portrait of James Pirruccello
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James Pirruccello, MD

Cardiology
Cardiology Mission Bay – Mission Bay Blvd. South
415-353-2873
Portrait of James Pirruccello
Portrait of James Pirruccello
ucsf logo

James Pirruccello, MD

Cardiology
Cardiology Mission Bay – Mission Bay Blvd. South
415-353-2873

On this page

About me

Dr. James Pirruccello is a cardiologist who cares for patients with cardiovascular conditions, including aortic diseases (those involving the heart’s main artery). He has particular interests in disease prevention and genetics.

In his research, Pirruccello uses machine learning to create new ways of analyzing the heart; he applies genetics to better understand how cardiovascular disease progresses. He also develops tools for assessing the risk of cardiovascular disease before it occurs.

Pirruccello earned his medical degree at the Johns Hopkins University School of Medicine. He completed a residency in internal medicine and a fellowship in cardiovascular disease at Massachusetts General Hospital.

Education & training

Board certification

  • Cardiovascular Disease, American Board of Internal Med/Cardiovascular Dis
  • Internal Medicine, American Board of Internal Medicine

Fellowship

  • Cardiovascular Disease, Massachusetts General Hospital GME

Residency

  • Internal Medicine, Massachusetts General Hospital GME

Internship

  • Internal Medicine, Massachusetts General Hospital GME

Degree

  • MD, Johns Hopkins University School of Medicine

My expertise

Locations

    Reviews

    Average rating

    5
    5 out of 5 Stars
    62 ratings
    About provider reviews

    Showing 1-6 of 26 reviews

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    • 5 out of 5 Stars
      March 25, 2026

      All around good

    • 5 out of 5 Stars
      March 9, 2026

      Excellent visit with in depth explanation of relevant aspects

    • 5 out of 5 Stars
      March 3, 2026

      Excellent Physician!!

    • 5 out of 5 Stars
      February 25, 2026

      Dr Pirruccello was terrific: easy to talk to, a great listener, and a wonderful explainer of complex issues. I would recommend him without reservation to another patient seeking a cardiologist in SF.

    • 5 out of 5 Stars
      February 2, 2026

      Dr. Pirruccello is the best! I am so grateful to have him as a part of my care team!

    • 5 out of 5 Stars
      September 25, 2025

      This was my first visit with him (referred by Dr. Grandis after his retirement), and I got a really good impression of him! He spent time listening, explaining, answering questions. Was very friendly, seemed genuinely concerned about my condition and needs, and his expertise and knowledge came through. But in a very down to earth way. Great first impression.

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