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Jon Kleen


Neurologist and epilepsy specialist
Brain fanatic, computer programmer, devoted coffee drinker

Dr. Jon Kleen is a neurologist who specializes in epilepsy care. He is dedicated to improving the lives of patients with epilepsy by stopping seizures and finding new ways to overcome epilepsy-related cognitive issues, such as memory problems.

Kleen is a neuroscientist with expertise in signal processing (the use of computers to study patterns in large amounts of data), which he applies to cutting-edge diagnostic approaches and emerging therapies for epilepsy, including brain stimulation. As part of his research, he investigates how memory circuits work in the human brain and why they are disrupted in many people with epilepsy. He also develops technology that integrates brainwave recordings with brain images to help pinpoint where seizures start, with the goal of increasing the chance for future curative surgery in patients whose prior treatments failed.

Kleen earned a doctorate in neuroscience from Dartmouth College and his medical degree from the Dartmouth Geisel School of Medicine. At UCSF, he completed a residency in neurology, serving as chief resident, and a fellowship in epilepsy. He also completed postdoctoral training in human neurophysiology at UCSF. In 2017, he was elected by UCSF medical students for membership in UCSF's chapter of Alpha Omega Alpha for excellence in teaching.

Kleen enjoys spending his free time with family, as well as practicing Spanish and basic Mandarin, bicycling in Golden Gate Park, watching the ocean from San Francisco's landmark Sutro Baths, and getting lost in Wikipedia.

  • Education

    Dartmouth College, PhD, Neuroscience, 2011

    Geisel School of Medicine, MD, 2013

  • Residencies

    UCSF, Neurology, 2017

  • Fellowships

    UCSF, Epilepsy, 2019

  • Academic Title

    Assistant Professor

My patients have taught me the most important lessons about epilepsy. They are the driving force behind my goals in neuroscience research.

Where I see patients (1)

    My reviews


    Overall Experience
    39 Ratings
    About our process
    Oct 07, 2023
    Very attentive the Doctor and we explain everything very well
    Sep 09, 2023
    Dr. Kleen is always so kind every time I visit him. He thoroughly looks out for each patient and makes sure to listen to them.
    Jul 08, 2023
    Dr Kleen is a caring Dr who cares about his Patients
    Jun 10, 2023
    Dr. Kleen is an excellent doctor and always provides me with the best of care
    Apr 13, 2023
    Dr. Kleen was amazing. I had a seizure during our appointment and he made sure to continue calling me back until he was absolutely sure that I was okay and discussed my episode. He is one of the best and most caring doctors I have come into contact with.
    Mar 19, 2023
    Dr. Kleen is always patient and communicative and makes sure we're on the sand page about the care plan each time we have a visit.
    Dec 14, 2022
    I have never had a provider show so much interest in my health or listened to me as much as Dr Kleen does.
    Nov 28, 2022
    Dr. Kleen always allows me plenty of room to speak and voice my opinions. Our conversations are never one sided he listens to what I have to say and takes my thoughts and ideas seriously. Dr. Kleen always provides a safe comfortable place to discuss and I feel a bit more relieved after each visit.
    Jul 26, 2022
    I feel fortunate to work with Dr. Kleen. At baseline he is obviously a smart and very capable doctor. Why I switched care to him full time a few years ago from CPMC is that he is a kind and warm person. He remembers our conversations and the big things that have been happening in my life. He seems to really care about me as a whole person.
    Jul 23, 2022
    Dr. Kleen is the best neurologist that I have had. He is kind friendly and has a great attitude each time I see him. He genuinely wants to address concerns of each patient and wants to find a solution.
    Apr 16, 2022
    The BEST Doctor in all my life he really takes care of his patient. I visited too many doctors like 6 and nothing changed. The only that really took care about my condition was him my doctor Jonathan. I haven't have more seizures. I do not have words to say how blessed I am because I found him.

    Selected research