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Dr. Jon Kleen is a neurologist who specializes in epilepsy care. He is dedicated to improving the lives of patients with epilepsy by stopping seizures and finding new ways to overcome epilepsy-related cognitive issues, such as memory problems.

Kleen is a neuroscientist with expertise in signal processing (the use of computers to study patterns in large amounts of data), which he applies to cutting-edge diagnostic approaches and emerging therapies for epilepsy, including brain stimulation. As part of his research, he investigates how memory circuits work in the human brain and why they are disrupted in many people with epilepsy. He also develops technology that integrates brainwave recordings with brain images to help pinpoint where seizures start, with the goal of increasing the chance for future curative surgery in patients whose prior treatments failed.

Kleen earned a doctorate in neuroscience from Dartmouth College and his medical degree from the Dartmouth Geisel School of Medicine. At UCSF, he completed a residency in neurology, serving as chief resident, and a fellowship in epilepsy. He also completed postdoctoral training in human neurophysiology at UCSF. In 2017, he was elected by UCSF medical students for membership in UCSF's chapter of Alpha Omega Alpha for excellence in teaching.

Kleen enjoys spending his free time with family, as well as practicing Spanish and basic Mandarin, bicycling in Golden Gate Park, watching the ocean from San Francisco's landmark Sutro Baths, and getting lost in Wikipedia.

  • Board Certifications

    American Board of Psychiatry and Neurology, Epilepsy, 2020

    American Board of Psychiatry and Neurology, Neurology, 2017

  • Fellowships

    UCSF, Epilepsy, 2019

  • Residencies

    UCSF, Neurology, 2017

  • Internship

    UCSF, Internal Medicine, 2014

  • Education

    Geisel School of Medicine at Dartmouth, 2013

  • Languages

    English

My patients have taught me the most important lessons about epilepsy. They are the driving force behind my goals in neuroscience research.

Where I see patients (1)

    My reviews

    4.9

    Overall Experience
    41 Ratings
    About our process
    Mar 27, 2025
    Give Dr. Kleen a raise!
    Mar 21, 2025
    Provider is reliable and trustworthy
    Mar 21, 2025
    Very grateful to have Dr. Kleen as my epilepsy neurologist
    Oct 01, 2024
    Dr. Kleen is very caring and takes the time to address and answer any problems you currently are experiencing. He is a great doctor and I would recommend him to anyone I know.
    Sep 23, 2024
    Dr. Kleen always listens to me and has been very supportive.
    Jun 24, 2024
    Dr. Kleen is kind, respectful and knowledgeable
    Jun 24, 2024
    Everything about each and every one of my interactions with Dr. Johnathan Kleen are beyond satisfactory. Each appointment and the content addressed in it always exceed expectation. Always. I am grateful.
    May 06, 2024
    Couldn't ask for a better experience! Thank you all;)
    Apr 04, 2024
    I love Dr. Klein! He is the best Dr. I've dealt with thus far.
    Oct 07, 2023
    Very attentive the Doctor and we explain everything very well
    Sep 09, 2023
    Dr. Kleen is always so kind every time I visit him. He thoroughly looks out for each patient and makes sure to listen to them.
    Jul 08, 2023
    Dr, Kleen is a caring Dr, who cares about his Patients
    Jun 10, 2023
    Dr. Kleen is an excellent doctor and always provides me with the best of care

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