Portrait of Jon Kleen
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Jon Kleen, MD, PhD

Epilepsy Neurology • Neurology
Epilepsy & Seizures Program Parnassus
415-353-2273
Portrait of Jon Kleen
Portrait of Jon Kleen
ucsf logo

Jon Kleen, MD, PhD

Epilepsy Neurology • Neurology
Epilepsy & Seizures Program Parnassus
415-353-2273

On this page

About me

Dr. Jon Kleen is a neurologist who specializes in epilepsy care. He is dedicated to improving the lives of patients with epilepsy by stopping seizures and finding new ways to overcome epilepsy-related cognitive issues, such as memory problems.

Kleen is a neuroscientist with expertise in signal processing (the use of computers to study patterns in large amounts of data), which he applies to cutting-edge diagnostic approaches and emerging therapies for epilepsy, including brain stimulation. As part of his research, he investigates how memory circuits work in the human brain and why they are disrupted in many people with epilepsy. He also develops technology that integrates brainwave recordings with brain images to help pinpoint where seizures start, with the goal of increasing the chance for future curative surgery in patients whose prior treatments failed.

Kleen earned a doctorate in neuroscience from Dartmouth College and his medical degree from the Dartmouth Geisel School of Medicine. At UCSF, he completed a residency in neurology, serving as chief resident, and a fellowship in epilepsy. He also completed postdoctoral training in human neurophysiology at UCSF. In 2017, he was elected by UCSF medical students for membership in UCSF's chapter of Alpha Omega Alpha for excellence in teaching.

Kleen enjoys spending his free time with family, as well as practicing Spanish and basic Mandarin, bicycling in Golden Gate Park, watching the ocean from San Francisco's landmark Sutro Baths, and getting lost in Wikipedia.

Education & training

Board certification

  • Epilepsy, American Board of Psychiatry and Neurology
  • Neurology, American Board of Psychiatry and Neurology

Fellowship

  • Epilepsy, UCSF Graduate Medical Education

Residency

  • Neurology, UCSF Graduate Medical Education

Internship

  • Internal Medicine, UCSF Graduate Medical Education

Degree

  • MD, Dartmouth Medical School

My expertise

Locations

    Reviews

    Average rating

    5
    5 out of 5 Stars
    50 ratings
    About provider reviews

    Showing 1-6 of 17 reviews

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    • 5 out of 5 Stars
      November 16, 2025

      Literally 5 on all because my doctor is a rock in my life. Can't do this without him. Seriously

    • 5 out of 5 Stars
      October 19, 2025

      Thank you Dr. Kleen for being the best doctor I could ask for. I really appreciate your guidance, expertise, and support.

    • 5 out of 5 Stars
      October 18, 2025

      My Nuerologist is great

    • 5 out of 5 Stars
      September 4, 2025

      Dr Kleen is the best. Give that guy a raise!

    • 5 out of 5 Stars
      August 31, 2025

      I had a video appointment with Dr. Kleen, who is an expert in neurological disorders and epilepsy in particular. I was impressed by his professionalism, expertise, and empathy. He spent an hour with me going over the details of my illness, listening to my concerns, going over my previous treatment, and finding better alternatives for my medication. He surpassed all my expectations. He is an outstanding doctor. Thank you so much, Dr. Keen!

    • 5 out of 5 Stars
      July 5, 2025

      Dr. Kleen has been very helpful and I appreciate his expertise. He handles delicate situations with precision and understanding that no two situations or people are the same.

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    For informational purposes only, a link to the federal Centers for Medicare and Medicaid Services (CMS) Open Payments web page is provided here. The federal Physician Payments Sunshine Act requires that detailed information about payment and other payments of value worth over ten dollars ($10) from manufacturers of drugs, medical devices, and biologics to physicians and teaching hospitals be made available to the public.