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Dr. Marc Simon is a cardiologist who specializes in pulmonary hypertension (a type of high blood pressure affecting the right side of the heart), advanced heart failure and heart transplantation. Among the patients he cares for are those with right-sided heart failure, which can result from pulmonary hypertension. He has experience with all methods of diagnosis, including right heart catheterization (in which a small tube called a catheter is threaded through a blood vessel to reach the heart), performing the test with patients at rest as well as during exercise. He directs UCSF's programs in pulmonary vascular disease and pulmonary hypertension.

Simon's research focuses primarily on developing new therapies for pulmonary hypertension as well as a better understanding of right-sided heart failure in patients with that condition.

He also has applied his background in bioengineering to heart biomechanics, studying how the heart can fail in cases of pulmonary hypertension. He has helped design several clinical trials (studies using human volunteers to evaluate promising new treatments) and directs ongoing trials of new medications and devices for pulmonary hypertension and heart failure.

Simon earned his medical degree from the University of Maryland School of Medicine. He completed a residency in cardiology at the University of Colorado School of Medicine. He completed a fellowship in cardiology and heart failure and a fellowship in cardiac transplantation at the University of Pittsburgh.

  • Board Certifications

    American Board of Internal Medicine, Advanced Heart Failure & Trans, 2010

    American Board of Internal Medicine, Cardiovascular Disease, 2004

  • Fellowships

    University of Pittsburgh School of Medicine, Advanced Heart Failure and Transplant Cardiology, 2005

    University of Pittsburgh School of Medicine, Cardiovascular Disease, 2004

  • Residencies

    University of Colorado School of Medicine, Internal Medicine, 2001

  • Internship

    University of Colorado School of Medicine, Internal Medicine, 1999

  • Degree

    University of Maryland School of Medicine, 1998

  • Languages

    English

Where I see patients (3)

    My reviews

    4.9

    Overall Experience
    199 Ratings
    About our process
    Jun 13, 2025
    Excellent
    Apr 16, 2025
    I'm really grateful to Dr. Simon for listening and helping me through this. He's been very understanding and empathetic while I'm dealing with getting surgery.
    Apr 06, 2025
    Dr. Simon was excellent. Sincere thanks!
    Apr 04, 2025
    Dr. Simon always listens to my concerns. He's great at answering my questions in a manner I can understand. He clearly presents the pros and cons. Then we decide together the best path forward for my treatment. Dr. Simon is a very good listener and he has a very approachable manner.
    Apr 04, 2025
    Dr. Simon is an incredible doctor! I highly recommend him! He takes his time and listens and is extremely knowledgeable
    Mar 14, 2025
    Dr. Simon was thorough, connected all the dots and took a comprehensive view of my condition. Also initiated a series of tests to narrow the treatment. He was pleasant and professional and took the time to respond to queries.
    Jan 24, 2025
    Very caring a great listener, answers all my question and concerns
    Dec 27, 2024
    Dr Simon is such a knowledgeable Dr. I appreciate being a patient of his. Additionally - he's kind and very caring.
    Oct 11, 2024
    Dr. Simon listens to my concerns. He does an excellent job explaining my condition in terms I understand and how I can effect positive changes to improve my condition.
    Sep 28, 2024
    Good
    Jul 21, 2024
    Staff and doctor was very pleasant.
    Jul 04, 2024
    Very satisfied and happy nothing negative thank you all for your assistance and kindness provided
    Jun 21, 2024
    Very competent and also kind!
    Jun 21, 2024
    Dr Simon is thoughtful, courteous, respectful and Takes the time to listen
    Jun 15, 2024
    Excellent care explaining how to clean the area. Very thoughtful.
    Jun 05, 2024
    Good
    Jun 04, 2024
    Excellent
    Jun 03, 2024
    She was totally professional and very kind.
    May 25, 2024
    He really cared and showed a lot of concern and understanding.
    May 22, 2024
    UCSF is the best place for any medical care needed!
    May 19, 2024
    Never talked to the provider or his assistiant.
    May 14, 2024
    Good
    Mar 29, 2024
    Dr. Simon is extremely, professional, kind and compassionate
    Nov 15, 2023
    Perfect, everything, thank you very much
    Sep 18, 2023
    Zero complaints - All Good!!
    Sep 08, 2023
    Learning more about my condition
    Sep 06, 2023
    Very much impressed with how everyone took care of me
    Sep 05, 2023
    I just love it when a doctor says things like let's look at the overall picture, let's put all we know together with the data. I can't remember if this is exactly what he said but you get the point. It is very reassuring to think that someone is doing this for me. He wasn't just checking his box. He Is amazing, keep him happy and give him a raise.
    Decorative Caduceus

    Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)

    Percentage of Treatment group patients experiencing any device-related Major Adverse Cardiovascular or Neurological Events (MACNE) during the first 90-days after implantation

    Recruiting

    Decorative Caduceus

    Metformin for Pulmonary Hypertension HFpEF

    Recruiting

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