Portrait of Samuel J. Pleasure
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Samuel J. Pleasure, MD

Neurology
Multiple Sclerosis & Neuroinflammation Center Mission Bay
415-353-2069
Portrait of Samuel J. Pleasure
Portrait of Samuel J. Pleasure
ucsf logo

Samuel J. Pleasure, MD

Neurology
Multiple Sclerosis & Neuroinflammation Center Mission Bay
415-353-2069

On this page

About me

Dr. Samuel J. Pleasure is a neurologist who specializes in caring for patients with multiple sclerosis. He also has expertise in caring for patients with epilepsy as well as years of experience in managing a variety of neurological conditions in both clinic and hospital settings.

Pleasure has two main areas of inquiry for his research. He studies processes that regulate early brain development in both normal and diseased situations. He also studies autoimmune forms of meningoencephalitis, where inflammation in specific brain areas causes severe neurologic dysfunction.

Pleasure received his medical degree and a doctorate in neuroscience from the University of Pennsylvania. He was chief resident during his neurology residency at UCSF, where he then completed a research fellowship in neuroscience.

Pleasure is a fellow of the American Neurological Association and a member of the American Academy of Neurology, American Epilepsy Society, Society for Neuroscience, Society for Developmental Biology and Cajal Club. He has won numerous awards for his research and has received research funding from a wide variety of private, state and federal sources. He has served in leadership roles in national organizations and in the UCSF Department of Neurology.

Pleasure is the Glenn W. Johnson, Jr. Memorial Endowed Chair in Neurology at UCSF.

Education & training

Board certification

  • Neurology, American Board of Psychiatry and Neurology

Degree

  • MD, University of Pennsylvania School of Medicine

My expertise

Locations

    Reviews

    Average rating

    4.9
    4.9 out of 5 Stars
    59 ratings
    About provider reviews

    Showing 1-6 of 17 reviews

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    • 5 out of 5 Stars
      December 10, 2025

      Dr Pleasure is an exceptional physician. He is so smart and knowledgeable. He explained everything to us, even things that other physicians missed. He is an amazing doctor. We are so lucky to have met with him. He is THE BEST and he is very nice too!

    • 5 out of 5 Stars
      August 21, 2025

      Besides the 1.5 hr drive every thing else was top notch I'm glad I was able to get in so quickly

    • 5 out of 5 Stars
      August 15, 2025

      Dr. Samuel Pleasure Is amazing.

    • 4.6 out of 5 Stars
      July 2, 2025

      The whole experience was good

    • 5 out of 5 Stars
      June 13, 2025

      Visit was a pleasure

    • 5 out of 5 Stars
      June 12, 2025

      The visit was very efficient, I felt listened to and am confident in my next steps. Outstanding care.

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