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Bruce Cree


Clinical Research Director at the UCSF Multiple Sclerosis Center
New therapy investigator, honored educator, multiple sclerosis specialist

Dr. Bruce Cree is a neurologist with a special interest in multiple sclerosis. He treats patients with multiple sclerosis, neuromyelitis optics, transverse myelitis and other autoimmune and central nervous system disorders. Cree currently serves as the clinical research director at the UCSF Multiple Sclerosis Center.

Cree's research focuses on the role of genetics in multiple sclerosis, the immunology of neuromyelitis optica and developing new treatments for multiple sclerosis and neuromyelitis optica through clinical trials.

Cree received his medical degree and doctorate in biochemistry from UCSF. He completed his neurology residency at Columbia University followed by a neurology fellowship at UCSF. He also earned a masters in advanced studies in clinical research from the department of epidemiology and biostatistics at UCSF.

Cree is a member of the American Academy of Neurology, the American Neurological Association and the San Francisco Neurological Society. He is an associate professor of neurology at the UCSF School of Medicine.

  • Education

    UCSF School of Medicine, 1997

  • Residencies

    Columbia Presbyterian Medical Center, Neurology, 2001

  • Fellowships

    UCSF Medical Center, Neurology, 2003

  • Board Certifications

    Neurology, American Board of Psychiatry and Neurology.

  • Academic Title


I divide my time among patient care, research and teaching. My studies focus on understanding disease progression and developing novel therapies.

Where I see patients (1)

    My reviews


    Overall Experience
    189 Ratings
    About our process
    Mar 03, 2023
    Always recommend MS Clinic. Excellent Experience!!!!
    Mar 02, 2023
    Dr. Cree is professional and thorough. His explanations are excellent.
    Feb 11, 2023
    Dr. Cree great at explaining my treatment options and is concerned about my health. He is professional and knows what he is talking about.
    Jan 12, 2023
    I returned to see Dr. Cree for his consultation on to use Uplizna. Dr. Cree helped me to make decision he also provided me more options on the new drugs. I switched to Stanford doctor three some years ago because it was closer to my home.
    Jan 12, 2023
    Outstanding. UCSF is amazing
    Dec 07, 2022
    I have always liked Dr. Cree and if anything I feel like his demeanor has become friendlier over time.
    Dec 06, 2022
    I feel very fortunate to be seen by Dr. Cree.
    Dec 06, 2022
    Oct 27, 2022
    Dr Cree is a very good MS doctor due to his knowledge/experience however is very cold and clinical not friendly at all . I always feel worse after seeing him.
    Oct 05, 2022
    Dr. Cree is very professional helpful understanding and friendly.
    Sep 22, 2022
    Probably the worst doctor I have ever seen. Zero care or compassion. Completely uninterested in me as a patient. Told me "I could look for care elsewhere" when I expressed frustration in waiting two months for an appt and finding out due to an error on his end that he didn't have all the tests he needed from me.
    Sep 16, 2022
    Care provider was dismissive of my concerns disrespectful of my thoughts and made me feel that he wanted my treatment to be successful to use it in his research study. He was distant and lacked bed-side manners.
    Sep 08, 2022
    Very good. I just don't know why Healthcare has become such a customer service orientated business. It's healthcare concentrate on the health of individuals.
    Aug 18, 2022
    Aug 11, 2022
    He's fantastic
    Aug 05, 2022
    Dr. Cree was excellent. He thoroughly explained results and options.
    Jun 09, 2022
    Dr cree was very thorough in his review of my records. He answered all my questions in a way I could understand .
    May 05, 2022
    Dr. Cree had suggested an in-person visit since the matter under discussion was complex and didn't lend itself to MyHealth. He was adept at efficiently and comprehensively explaining the rationale for the proposed plan addressed questions and included my/our concerns in arriving at a plan of action.
    Feb 16, 2022
    I have found visits and after care documented well. Making follow up appts is much easier now that a follow up notices and link is provided as a request to book the follow up appt.
    Dec 08, 2021
    Appreciated careful review of complex medical history/circumstances to arrive at decisions about next steps
    Nov 03, 2021
    I am extremely pleased with the care Dr. Cree provides. He is knowledgeable patient and easy to understand.
    Sep 30, 2021
    At times when I ask Dr Cree a question about my disease or treatment options I feel he responds as though I am challenging him. He is often dismissive and seems to want to shut down the conversation.
    Sep 24, 2021
    My Care Provider is The Best Ever!
    Sep 16, 2021
    Good discussion about flu shot vaccinations etc.
    Sep 13, 2021
    Dr. Cree is knowledgeable and has always done a great job answering questions and providing information. I like it that during my first or second visit with him he told me that he serves as a resource but that the decisions are up to me. I like his collaborative approach and much prefer that to a more dictatorial authoritarian approach. I also like that he is an MD/PhD and has both clinical skills of an MD and academic knowledge of a PhD that likely exceeds what someone with just an MD would have.
    Jun 29, 2021
    too much for me to grasping my present condition
    Jun 18, 2021
    Dr. Cree is one of the best doctors I have ever had. I always feel that he is an advocate and respectful clinician.
    May 11, 2021
    regarding "Friendliness/courtesy of the care provider" this is not important to me -- I care that Dr cree know what he is doing. (which he is)
    May 04, 2021
    Dr. Cree's patient relationship has really flourished over the years. I am thankful he allows me to make the decisions about my treatment plan when so many doctors are quick to tell me what to do rather than advise me of my options.
    Decorative Caduceus

    Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset

    Comparison of intrathecal synthesis of gammaglobulins in treatment-naïve relapsing MS and clinically isolated syndrome participants before and after 3 years of treatment with ocrelizumab. Intrathecal synthesis is measured by eithe...


    Decorative Caduceus

    Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor...

    Time to onset of 6 month CDP defined as follows: Increase of ≥1.0 point from the baseline expanded disability status scale (EDSS) score when the baseline score is ≤5.5, or Increase of ≥0.5 points when the baseline EDSS score is >...