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Bruce Cree


Clinical Research Director, UCSF Multiple Sclerosis Center
New therapy investigator, honored educator, multiple sclerosis specialist

Dr. Bruce Cree is a neurologist with a special interest in multiple sclerosis. He treats patients with multiple sclerosis, neuromyelitis optics, transverse myelitis and other autoimmune and central nervous system disorders. Cree currently serves as the clinical research director at the UCSF Multiple Sclerosis Center.

Cree's research focuses on the role of genetics in multiple sclerosis, the immunology of neuromyelitis optica and developing new treatments for multiple sclerosis and neuromyelitis optica through clinical trials.

Cree received his medical degree and doctorate in biochemistry from UCSF. He completed his neurology residency at Columbia University followed by a neurology fellowship at UCSF. He also earned a masters in advanced studies in clinical research from the department of epidemiology and biostatistics at UCSF.

Cree is a member of the American Academy of Neurology, the American Neurological Association and the San Francisco Neurological Society. He is an associate professor of neurology at the UCSF School of Medicine.

  • Education

    UCSF School of Medicine, 1997

  • Residencies

    Columbia Presbyterian Medical Center, Neurology, 2001

  • Fellowships

    UCSF Medical Center, Neurology, 2003

  • Board Certifications

    Neurology, American Board of Psychiatry and Neurology.

  • Academic Title


I divide my time among patient care, research and teaching. My studies focus on understanding disease progression and developing novel therapies.

Where I see patients (1)

    My reviews


    Overall Experience
    175 Ratings
    About our process
    Nov 17, 2023
    Yes I always speak on UCSF health care to my friends and co-workers.
    Nov 16, 2023
    I am so fortunate to have Dr. Cree as my neurologist. He is absolutely the best. I wish all my doctors were like him.
    Nov 10, 2023
    Dr. Bruce Cree is Awesome Provider Very Compassionate About My Whole Health Care!!
    Nov 10, 2023
    Dr. Cree is a very professional and competent neurologist.
    Nov 09, 2023
    Dr. Cree is an incredibly thorough and attentive doctor. He is clearly invested in solving the patients issues. His insight and help has greatly improved how I see my condition!
    Nov 08, 2023
    Diligent and went deep. Exactly what was hoping for in a diagnostic intro appointment.
    Nov 01, 2023
    Dr. Cree was very good to set up a last minute appointment for my concern over some vague findings on MRI. Dr. Cree took his time to discuss my concerns and did a detailed review of my scan. I was completely satisfied and felt much better after our discussion. I appreciate both his and staff's quick response.
    Oct 21, 2023
    Dr. Cree is very good about explaining the care treatment and alternative treatments. A tele-conference visit work fine for it was a follow up appointment regarding vaccines. Once a year it is important to have a in person visit to evaluate my physical health.
    Sep 30, 2023
    Dr Cree was exceptional in every way during my visit. He's knowledgeable professional thorough caring listened and explained everything so I understood gave his honest opinion to my questions and very compassionate. He's the best specialist I've ever seen in my life.
    Sep 28, 2023
    This was just a bad appointmentl. I was not happy with how short it was or how late it got started. Overall Dr. Cree is a great doctor
    Sep 27, 2023
    I have always felt that my doctor cares for my well being. He is very respectful and kind.
    Sep 16, 2023
    Dr. Cree is thorough knowledgeable and receptive to my input as well as willing to provide his own input to make treatment decisions collaboratively.
    Sep 06, 2023
    Dr. Cree was very thorough in taking my history and physical exam. I appreciated his detailed review of my scans.
    Aug 11, 2023
    Dr. Cree us an excellent Doctor. He is the reason we choose to go to UCSF for specialized care.He is professional but treats you like me compassion and kindness. A rare combination I have found in many Doctors especially in current medical practices.
    Aug 10, 2023
    Very kind and explained things in great detail to me.
    Aug 05, 2023
    I don't hide this. I have a word processing disability. An Inherited trait. And I had to teach myself how to write as best as I can. So sometimes I feel intimidated by people cause I can't ask good questions or express what's on my mind easily. (Even though I'm supposed to be so smart.) And I don't expect anyone to be a mind reader. I'm happy with doctors/professionals at UCSF. Dr Cree is precise. He explains things well and stops to clarify information I don't quite understand. That's precious. His passes on his vast knowledge of what I can improve on to help me deal with this MS. He's good on offering me meds and suggestions to make life better. I think that's makes him "the guy" who has the heart and drive to help people like me deal with this stupid problem. Thank you Dr. Cree!!
    Jul 26, 2023
    Thorough interview exam and assessment. It shows that provider is knowledgeable and professional. I loved the fact that he did a through interview of the history and took the time to make decisions based on his analysis of the facts.
    Jul 20, 2023
    I already recommend anyone with epilepsy or rare brain diseases is Clinic. This is Provider.
    Jul 19, 2023
    Dr. Cree listened and talked with us very well at this appointment. He even shared outside information that had happened to himself and his home.
    Jun 23, 2023
    Addressed health in general not just specialty.
    Jun 22, 2023
    I am treated with respect and care. I appreciate everything Dr Cree has done for me.
    Jun 09, 2023
    Dr.Cree is an exceptional care provider. I would respond excellent to each of the above questions if that were an option. He addresses my mental and emotional state with as much concern and attention as my physical issues.
    Jun 01, 2023
    Dr. Cree is the best!!!
    May 18, 2023
    Dr. Cree was excellent. He is extremely thorough empathetic and clear.
    Apr 06, 2023
    I've already referred Dr. Cree to several of my MS peers.
    Apr 01, 2023
    Best provider available listens to all concerns and spends appropriate time with patience.
    Mar 23, 2023
    Dr Cree really took time to help me think through my treatment
    Mar 18, 2023
    Very attentive and caring
    Mar 03, 2023
    Always recommend MS Clinic. Excellent Experience!!!!
    Mar 02, 2023
    Dr. Cree is professional and thorough. His explanations are excellent.
    Feb 11, 2023
    Dr. Cree great at explaining my treatment options and is concerned about my health. He is professional and knows what he is talking about.
    Jan 12, 2023
    I returned to see Dr. Cree for his consultation on to use Uplizna. Dr. Cree helped me to make decision he also provided me more options on the new drugs. I switched to Stanford doctor three some years ago because it was closer to my home.
    Jan 12, 2023
    Outstanding. UCSF is amazing
    Dec 07, 2022
    I have always liked Dr. Cree and if anything I feel like his demeanor has become friendlier over time.
    Dec 06, 2022
    I feel very fortunate to be seen by Dr. Cree.
    Dec 06, 2022
    Oct 27, 2022
    Dr Cree is a very good MS doctor due to his knowledge/experience however is very cold and clinical not friendly at all . I always feel worse after seeing him.
    Oct 05, 2022
    Dr. Cree is very professional helpful understanding and friendly.
    Sep 22, 2022
    Probably the worst doctor I have ever seen. Zero care or compassion. Completely uninterested in me as a patient. Told me "I could look for care elsewhere" when I expressed frustration in waiting two months for an appt and finding out due to an error on his end that he didn't have all the tests he needed from me.
    Sep 16, 2022
    Care provider was dismissive of my concerns disrespectful of my thoughts and made me feel that he wanted my treatment to be successful to use it in his research study. He was distant and lacked bed-side manners.
    Sep 08, 2022
    Very good. I just don't know why Healthcare has become such a customer service orientated business. It's healthcare concentrate on the health of individuals.
    Aug 18, 2022
    Aug 11, 2022
    He's fantastic
    Aug 05, 2022
    Dr. Cree was excellent. He thoroughly explained results and options.
    Jun 09, 2022
    Dr cree was very thorough in his review of my records. He answered all my questions in a way I could understand .
    May 05, 2022
    Dr. Cree had suggested an in-person visit since the matter under discussion was complex and didn't lend itself to MyHealth. He was adept at efficiently and comprehensively explaining the rationale for the proposed plan addressed questions and included my/our concerns in arriving at a plan of action.
    Feb 16, 2022
    I have found visits and after care documented well. Making follow up appts is much easier now that a follow up notices and link is provided as a request to book the follow up appt.
    Decorative Caduceus

    Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor...

    Time to onset of 3-month cCDP defined as follows: Increase over at least 3 months of ≥1.0 point from the baseline expanded disability status scale (EDSS) score when the baseline score is ≤5.5, or ≥0.5 points when the baseline EDSS...