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Bruce Cree


Clinical Research Director at the UCSF Multiple Sclerosis Center
New therapy investigator, honored educator, multiple sclerosis specialist

Dr. Bruce Cree is a neurologist with a special interest in multiple sclerosis. He treats patients with multiple sclerosis, neuromyelitis optics, transverse myelitis and other autoimmune and central nervous system disorders. Cree currently serves as the clinical research director at the UCSF Multiple Sclerosis Center.

Cree's research focuses on the role of genetics in multiple sclerosis, the immunology of neuromyelitis optica and developing new treatments for multiple sclerosis and neuromyelitis optica through clinical trials.

Cree received his medical degree and doctorate in biochemistry from UCSF. He completed his neurology residency at Columbia University followed by a neurology fellowship at UCSF. He also earned a masters in advanced studies in clinical research from the department of epidemiology and biostatistics at UCSF.

Cree is a member of the American Academy of Neurology, the American Neurological Association and the San Francisco Neurological Society. He is an associate professor of neurology at the UCSF School of Medicine.

  • Education

    UCSF School of Medicine, 1997

  • Residencies

    Columbia Presbyterian Medical Center, Neurology, 2001

  • Fellowships

    UCSF Medical Center, Neurology, 2003

  • Board Certifications

    Neurology, American Board of Psychiatry and Neurology.

  • Academic Title


I divide my time among patient care, research and teaching. My studies focus on understanding disease progression and developing novel therapies.

Where I see patients (1)

    My reviews


    Overall Experience
    228 Ratings
    Explained things in a way that was easy to understand
    227 Ratings
    Did the doctor pay attention to your concerns
    228 Ratings
    Gave easy to understand instructions about taking care of health problems or concerns
    223 Ratings
    Knew the important information about your medical history
    226 Ratings
    The provider showed respect for what you had to say
    226 Ratings
    The provider spent enough time with me
    225 Ratings
    Decorative Caduceus

    Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset

    Comparison of intrathecal synthesis of gammaglobulins in treatment-naïve relapsing MS and clinically isolated syndrome participants before and after 3 years of treatment with ocrelizumab. Intrathecal synthesis is measured by eithe...


    Decorative Caduceus

    Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinas...

    Time to onset of 6 months CDP defined as follows: -Increase of ≥1.0 point from the baseline expanded disability status scale (EDSS) score when the baseline score is ≤5.0, or -Increase of ≥0.5 point when the baseline EDSS score is...


    Decorative Caduceus

    Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor...

    Time to onset of 6 month CDP defined as follows: Increase of ≥1.0 point from the baseline expanded disability status scale (EDSS) score when the baseline score is ≤5.5, or Increase of ≥0.5 points when the baseline EDSS score is >...