
Multiple Sclerosis & Neuroinflammation Center
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Why choose UCSF Health for multiple sclerosis or neuroinflammation treatment?
Experts at the UCSF Multiple Sclerosis and Neuroinflammation Center care for people with MS and other neuroinflammatory diseases. We're an internationally recognized center, caring for patients from around the world and known for our advances in treatments. Our team includes specialists across many fields who work together to create highly personalized care plans. From diagnosis to treatment, we use advanced tools that enable us to understand your condition better and help you feel your best.
We're known for our deep experience, compassionate approach and leading-edge research. We offer treatments that do more than slow the course of the disease; we're developing reparative and regenerative therapies to stop and reverse disease progression.
We welcome patients who are seeking second opinions or have not found answers elsewhere. Our goal is to provide world-class, personalized care that goes beyond traditional treatment, focusing on quality of life, recovery and comprehensive support.
Why choose UCSF Health for multiple sclerosis or neuroinflammation treatment?
Experts at the UCSF Multiple Sclerosis and Neuroinflammation Center care for people with MS and other neuroinflammatory diseases. We're an internationally recognized center, caring for patients from around the world and known for our advances in treatments. Our team includes specialists across many fields who work together to create highly personalized care plans. From diagnosis to treatment, we use advanced tools that enable us to understand your condition better and help you feel your best.
We're known for our deep experience, compassionate approach and leading-edge research. We offer treatments that do more than slow the course of the disease; we're developing reparative and regenerative therapies to stop and reverse disease progression.
We welcome patients who are seeking second opinions or have not found answers elsewhere. Our goal is to provide world-class, personalized care that goes beyond traditional treatment, focusing on quality of life, recovery and comprehensive support.
Complete care from an expert team
Our team includes experts in neurology, neuropsychology, rehabilitative medicine, urology, rheumatology and other fields.Global leaders in neuroinflammation care
We provide care for the most complex neuroinflammatory conditions, treating patients from over 30 countries.Advanced encephalitis and meningitis care
We lead research studies, focusing on bringing new encephalitis and meningitis treatments to our patients faster.Pioneers in neuroinflammatory research
We're the world's top recipient of research funding for neuroinflammatory disorders, enabling us to develop the next generation of treatments.
Advanced care for neuroinflammatory conditions
We take an integrated approach to care, customizing your team to your unique needs. Neuroinflammatory conditions affect the whole body, so you receive holistic care from experts in:
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Neurology
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Neuro-ophthalmology
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Neuropsychology
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Infectious diseases
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Urology
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Gastroenterology
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Rheumatology
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Rehabilitative medicine
You have seamless access to specialists across UCSF Health. They work together to figure out the treatment plan that can help you feel your best.
In addition to the latest treatments, we provide:
Advanced diagnostics
A precise diagnosis is the first step to personalized treatment. We use the most advanced tests available in our Neurodiagnostic Center to get a complete picture of the condition.
Specialized movement, vision, walking and functional tests help us create a treatment plan tailored to you. You may also receive a comprehensive neurocognitive evaluation from a neuropsychologist.
Holistic care for quality of life
We combine our diagnostic information with our research advances to identify which treatments will help you stay as healthy and independent as possible. Our research-driven regenerative therapies aim to restore function, not just preserve it. We provide care for your physical and mental health, including recommendations for activity, nutrition and stress management. Our sophisticated monitoring methods track your health in detail.
Our whole-person care includes:
- Physical therapists with expertise in neuroinflammatory diseases work with you to design an exercise program to help you stay active.
- Psychologists and social workers offer support and stress reduction techniques.
- Patient and family advisory council helps us understand how we can improve the care and support we provide. The council enables us to extend our care beyond medical treatment to address the social and personal impacts of neurological conditions.
Clinical trial opportunities
UCSF Health doctors are leading groundbreaking research to discover better treatments for MS, encephalitis, meningitis and other neuroinflammatory conditions.
We're working to discover and describe new neurological conditions and breakthrough treatments that aren't available anywhere else. Patients in our care often have access to clinical trials, giving them early access to the most promising new treatments.
Locations
Providers

Riley M. Bove, MD, MS
Neurology
Bruce Cree, MD, PhD
Neurology
Jeffrey M. Gelfand, MD
Neurology
Douglas S. Goodin, MD
Neurology • Clinical Neurophysiology
Award-winning care

Best in the West and No. 2 in the nation for neurology & neurosurgery
Related conditions & treatments
Conditions
- Autoimmune Encephalitis
- Demyelinating Disease
- Encephalitis
- Leukodystrophy
- Meningitis
- Multiple Sclerosis
- Neuroinflammatory Disorders
- Neuromyelitis Optica (NMO)
- Optic Neuritis
Treatments
- Botox for Spasticity
- Multiple Sclerosis (MS) Rehabilitation
Clinical trials
Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)Opens in a new window
PRISMA, is a pregnancy registry study, focused on comprehensively collecting information about pregnancy in women with chronic neurological conditions from across the United States and internationally."Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MSOpens in a new window
The goal of this observational study is to validate a novel, cost-effective method for real-world assessment using patient-acquired "selfie" videos in people with multiple sclerosis. The investigators aim to prove the feasibility and validity of monitoring walking changes remotely through a truly patient-centered, low-burden, low-cost approach. The main question this study aims to answer is: do remotely collected walking and speech videos from a mobile phone match the information investigators can gather from an in person visit?Development of Digital Biomarkers in Multiple Sclerosis: Validation Study 2Opens in a new window
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Diagnosis is established by clinical assessment of persons with MS (PwMS), in combination with imaging and body fluid assessments. Treatment decisions in MS are mainly based on periodic monitoring of disease activity and progression through clinical and imaging assessments.Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple SclerosisOpens in a new window
This study evaluates the effectiveness of N-acetyl cysteine (NAC) in the treatment of progressive multiple sclerosis. Half of the patients will receive NAC, while the other half will receive a placebo.Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple SclerosisOpens in a new window
This study will evaluate whether ofatumumab is excreted at quantifiable levels and at which concentrations in breast milk of lactating women with RMS). The study will include lactating mothers who plan to breastfeed and initiate/re-initiate ofatumumab 2-24 weeks post-partum.Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair TherapyOpens in a new window
The clinical trial is intended to assess for clinical evidence of Clemastine Fumarate as a myelin repair therapy in patients with acute inflammatory injury-causing demyelination as measured by multi-parametric MRI assessments.Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)Opens in a new window
The main purpose of this study is to assess clemastine as a remyelinating agent in patients with acute optic neuritis.The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with optic neuritis. Study procedures will include assessments for evidence of remyelination in the anterior visual pathway and in the brain using electrophysiologic techniques and magnetic resonance imaging. If they are on one, patients in this study can remain on their standard disease modifying treatment during the course of the study. However, patients cannot participate in any other investigational new drug research study concurrently.A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk
The primary objective of the lactation study is to characterize the presence and concentration of BRIUMVI™ in breast milk among breastfeeding participants who receive BRIUMVI™ therapeutically for the treatment of relapsing forms of multiple sclerosis (RMS).Emgality for Migraine in BreastmilkOpens in a new window
The goal of this project is to evaluate galcanezumab transfer into maternal breastmilk, and to evaluate infant (growth, development, constipation, colic, infections) and maternal (headache) outcomes for dyads in which the mother was treated with galcanezumab and to compare outcomes for infants who were or were not breastfed after maternal treatment.
Research initiatives
UCSF Multiple Sclerosis Center ResearchOpens in a new window
The UCSF Multiple Sclerosis Center's research program investigates potential new treatments and works to improve understanding of the disease, including the effects of genes, the environment and the immune system.UCSF Center for Encephalitis MeningitisOpens in a new window
The UCSF Center for Encephalitis & Meningitis team has experts in the many conditions that can cause encephalitis and meningitis. Our research focuses on developing better diagnostic tests to improve care for patients with these illnesses.






