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Dr. Iris Otani is an allergist and immunologist who cares for patients with a wide variety of allergic and immune deficiency conditions. With special expertise in evaluating medication allergies, she oversees UCSF's drug allergy testing program. In addition, she directs quality improvement and patient safety for the UCSF Allergy and Immunology Clinic and is associate director of the allergy and immunology fellowship program.

Otani's research focuses on improving care for patients with antibiotic allergies and chemotherapy reactions. She has streamlined antibiotic allergy evaluations for hospitalized and immunocompromised patients, and works to develop processes to ensure patients can safely continue chemotherapy after experiencing a reaction.

Otani earned her medical degree from the University of California, San Diego School of Medicine, where she also completed a National Institutes of Health research fellowship in immunology. She completed a residency in internal medicine at the Santa Clara Valley Medical Center.

  • Board Certifications

    American Board of Allergy and Immunology, Allergy and Immunology, 2016

    American Board of Internal Medicine, Internal Medicine, 2014

  • Fellowships

    Massachusetts General Hospital, Allergy/Immunology, 2016

  • Residencies

    Santa Clara Valley Medical Center, Internal Medicine, 2014

  • Internship

    Santa Clara Valley Medical Center, Internal Medicine, 2012

  • Degree

    UCSD, 2010

  • Languages

    English

I believe in partnering with patients throughout the decision-making process to optimize their care and quality of life.

Where I see patients (2)

    My reviews

    4.9

    Overall Experience
    73 Ratings
    About our process
    Apr 28, 2025
    Dr, Otani always shows great care and respect. She is very knowledgeable and thoughtful.
    Mar 22, 2025
    Very well
    Sep 20, 2024
    Dr. Otani is the ultimate professional, allowing space and time to sit with me and answer all of my questions and took time to explain things in language that I could understand.
    Feb 28, 2024
    ALL GOOD
    Feb 07, 2024
    My experience with Dr. Otani was excellent. She listened to me carefully, made me feel like a partner in my care, and provided especially helpful after-care instructions. Her notes and after visit summary were completely accurate and did not include any errors. I find there are often small errors in my notes or summaries, but hers were perfect. This was consistent with how carefully she listened to me and involved me in decision making. I generally believe that I am receiving good high quality care at UCSF, but Dr. Otani stands outs out for her excellent listening and attention. I felt and continue to feel meaningfully better from having seen her, separate from any treatment. I feel less anxious, more cared for, and more confident about next steps as I move forward with my high risk pregnancy.
    Jan 22, 2024
    Dr Otani provided excelllent care as always!
    Dec 19, 2023
    Dr. Otani is an excellent doctor. I would recommend to anyone.
    Dec 08, 2023
    I have been a UCSF patient for more than 10+ years and have always gotten very good service
    Dec 03, 2023
    A very good experience
    Nov 26, 2023
    1st visit with these two Drs. Will be in coordination with my Primary and other 2 Physicians at UCSF. We are only getting started on plans.
    Nov 05, 2023
    Dr Otani is very knowledgable and she takes the time to listen to my questions and concerns. My medical history is complicated, making it difficult to come up with a diagnosis and treatment plan. This is why I was referred to UCSF. I very much appreciated Dr Otani's efforts in this regard.
    Sep 06, 2023
    I'm very grateful for her experience.
    Sep 01, 2023
    Dr. Otani is professional, caring, and kind.
    Aug 18, 2023
    They were so awesome - caring and great listeners!

    Selected research

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