Portrait of Matilda Chan
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Matilda Chan, MD, PhD

Cornea and External Diseases • Ophthalmology
Ophthalmology & Optometry Mission Bay
415-353-2020
Portrait of Matilda Chan
Portrait of Matilda Chan
ucsf logo

Matilda Chan, MD, PhD

Cornea and External Diseases • Ophthalmology
Ophthalmology & Optometry Mission Bay
415-353-2020

On this page

About me

Dr. Matilda Chan is an ophthalmologist who specializes in caring for adults with infectious and inflammatory diseases of the ocular surface and eyelids. She treats patients with dry eye syndrome, blepharitis (eyelid inflammation that can affect tear production), meibomian gland dysfunction (a blockage that can cause dry eyes), Sjӧgren's syndrome (an autoimmune disorder that causes dry eyes), and corneal ulcers.

In her research, Chan is exploring the underlying causes of corneal opacification (scarring or clouding of the cornea that affects vision) and Fuchs endothelial corneal dystrophy (a disease in which corneal swelling and clouding causes a gradual decline in vision). She is working to develop new ways to treat corneal blindness.

Chan earned her medical degree and doctoral degree in biochemistry at the Keck School of Medicine of the University of Southern California. She completed her residency in ophthalmology at the University of Rochester Flaum Eye Institute, and a fellowship in cornea and external disease at UCSF.

Chan belongs to the American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, International Society for Eye Research and Women In Ophthalmology.

Education & training

Board certification

  • Ophthalmology, American Board of Ophthalmology

Residency

  • General Practice Residency, Rochester General Hospital

Internship

  • University of California - San Diego

Degree

  • MD, University of Southern California

Locations

    Reviews

    Average rating

    4.9
    4.9 out of 5 Stars
    108 ratings
    About provider reviews

    Showing 1-6 of 27 reviews

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    • 5 out of 5 Stars
      January 30, 2026

      Love Dr Chan. The only one who has been able to figure out what's going on with my dry eyes and brings forth helpful solutions in a caring manner. Very grateful to have her as part of my eye care team

    • 5 out of 5 Stars
      January 7, 2026

      Dr. Chan is amazing - competent, thorough, and very nice.

    • 5 out of 5 Stars
      October 1, 2025

      The best! Knowledgeable, great listener, warm, and friendly, always has a plan

    • 5 out of 5 Stars
      September 24, 2025

      Dr Chan was fantastic. After seeing so many optometrists and being on treatments that haven't worked to improve my dry eyes for the past two years she was able to put me on a regimen that I'm hoping will make a difference. She explained her reasoning and scheduled close follow up. Ensured she would send her note to my local optometrist so they are in the loop.

    • 5 out of 5 Stars
      September 24, 2025

      I drive 4 hours 1 way to get the A team. The healthcare where I live is often dreadful, but we have some good surgeons . Very weak on diagnosis and keeping up with current medical news and treatment options

    • 5 out of 5 Stars
      July 23, 2025

      She's the best!!!!

    Please check with your health insurance plan regarding coverage for this type of care. Not all providers at UCSF Health are covered by every insurance plan.

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