Anthony Shum, MD

Pulmonologist

Dr. Anthony Shum is an associate professor of medicine in the Department of Pulmonary and Critical Care at UCSF. After his clinical fellowship at UCSF, he received research training in immune tolerance as part of the Immunology Program at UCSF. The focus of his lab's research (shumlab.ucsf.edu) is to understand the pathogenesis of autoimmune lung diseases by intensively studying patients with these disorders and modeling their disease in mice. Through Shum's work he identified a novel lung-specific antigen named BPIFB1 that is targeted in patients with autoimmune lung disease and demonstrated that autoantibodies to BPIFB1 could be used as a biomarker to detect patients with lung autoimmunity. His lab also recently helped discover the genetic basis of a novel Mendelian syndrome of autoimmunity manifested by lung and joint disease that is coined the COPA syndrome, based on the gene that is mutated in this disorder. Through his research Shum hopes to discover diagnostic and interventional targets that will ultimately lead to biomarkers and therapies that will directly impact patient care.

ILD Program
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143
Phone: (415) 353-2577
Fax: (415) 353-8944

• COPA Syndrome

• Interstitial Lung Disease