Español  |

Updated Nov. 29, 2022

Note: UCSF is now offering updated COVID-19 boosters to anyone who’s at least 5 years old. You don’t have to be a UCSF patient. The new boosters provide improved protection against the most common variants of COVID-19 making people sick today. UCSF doctors are recommending this safe and effective updated shot. (If you recently had a COVID vaccine of any type, you need to wait two months before getting the updated booster.) Schedule an appointment now through MyChart or by calling (415) 476-3307.


COVID-19 vaccines remain the best public health measure to protect people from the virus, slow transmission and reduce the likelihood of new variants emerging. 

UCSF Health offers COVID-19 vaccines to anyone who is eligible, not just UCSF patients. If you're seeking a booster shot, see information about eligibility below.

Who's eligible for the COVID-19 vaccine

Everyone who's at least 6 months old is eligible for a COVID-19 vaccine. Learn more about COVID-19 vaccines for kids at UCSF Benioff Children's Hospitals.

Where to get the COVID-19 vaccine

Pfizer, Moderna and Novavax COVID-19 vaccines require two doses and two appointments. When you get your first dose, we'll schedule your second. (Pfizer and Moderna are preferred in most situations.)

Anyone who is eligible can get a vaccine at UCSF's Laurel Heights and Mission Bay clinics. You do not need to be a UCSF patient.

  • Laurel Heights campus (ages 6 months+; general public)
    3333 California St.
    San Francisco, CA 94418
    Hours: M-F, 8 a.m. - 4 p.m. (closed noon - 1 p.m.)
    We strongly recommend making an appointment. Schedule through MyChart or by calling (415) 476-3307.
  • Mission Bay campus (ages 6 months+; general public)
    601 16th St. (corner of 16th and Owens streets)
    San Francisco, CA 94158
    Hours: Mondays and Fridays, 7:30 a.m. - 7 p.m. | Wednesdays, 8 a.m. - 4 p.m. (closed noon - 1 p.m. all days)
    We strongly recommend making an appointment. Schedule through MyChart or by calling (415) 476-3307.  

For some patients, it may be quicker to get the vaccine at their local pharmacy or vaccination clinic. To schedule an appointment, visit your pharmacy's website, your county's vaccine website, California's My Turn, or the national site.

More information about vaccine appointments for kids


COVID-19 booster shots

U.S. health officials have approved COVID-19 booster shots for all adult recipients of the Pfizer, Moderna and Johnson & Johnson vaccines. The latest boosters, known as bivalent boosters, are designed to target COVID-19's Omicron subvariants better than the original monovalent boosters, which are no longer offered. To learn more, read our FAQs about the updated boosters.

All adults should get this updated booster at least two months after their most recent shot, whether that was the second dose of a primary series or a monovalent booster.

(For information about booster eligibility for children, see our pediatric COVID-19 vaccine page.) 

You can receive your booster at one of the UCSF vaccination sites listed above, and you may choose either Pfizer or Moderna for this booster, regardless of which vaccine you initially received. 

To select a particular booster, schedule an appointment through MyChart or by calling (415) 476-3307. Vaccine inventory can vary, and we can't guarantee we'll have the booster you want if you walk in without an appointment.

You can also schedule booster shots with some primary care physicians or at a local pharmacy.

Johnson & Johnson eligibility

If you received the Johnson & Johnson single-dose vaccine, you should get an updated Moderna or Pfizer booster at least two months after your most recent shot, whether that was a single dose of J&J or a monovalent booster.

Moderna and Pfizer eligibility

If you received Moderna or Pfizer, you should get an updated booster at least two months after your most recent shot, whether that was the second dose of a primary series or a monovalent booster.

The purpose of an updated booster shot – which helps maximize and extend the protection that the COVID-19 vaccine provides and strengthen protection against the Omicron subvariants – is different from an "additional dose" of the vaccine, which was approved in August 2021 for immunocompromised patients. (If you're immunocompromised, find out about eligibility for additional shots of either Pfizer or Moderna in the next section.)

Additional doses for immunocompromised patients

Moderately to severely immunocompromised patients who received the Pfizer or Moderna vaccine should get three vaccine doses and an updated booster (four shots in total), according to the Centers for Disease Control and Prevention (CDC). The third dose can provide additional protection to those whose immune system didn't fully respond to the initial two doses.

The CDC recommends an additional dose and updated booster of an mRNA vaccine (Pfizer or Moderna) for patients who received the Johnson & Johnson vaccine. See details about the recommended doses and timeline for your situation.

All immunocompromised adults should receive an updated booster two months after their most recent vaccine dose or monovalent booster. For patients who followed the CDC's prior booster guidelines, this updated booster could be their fifth or sixth shot.

UCSF Health is offering third doses and boosters to eligible patients. See above for our locations, plus where to book an appointment for a shot in your community. UCSF Benioff Children's Hospital Oakland also offers additional doses for immunocompromised patients at the hospital's Outpatient Center.


You're considered immunocompromised and eligible for a third dose if you:

  • Are receiving treatment for tumors or blood cancer
  • Have received an organ transplant and are taking medication to suppress your immune system
  • Have received a stem cell transplant within the last two years or are taking medicine to suppress your immune system
  • Have a condition that moderately or severely impairs immune function
  • Have advanced or untreated HIV infection
  • Are taking high-dose corticosteroids or other medications that suppress immune function

Guidelines for immunocompromised patients

If you received a two-dose Pfizer or Moderna vaccine series you should get:

  • third vaccine dose of Pfizer or Moderna more than one month after your second dose. 
  • An updated booster shot of Pfizer or Moderna at least two months after your third vaccine dose or most recent monovalent booster.

You can mix and match Pfizer and Moderna vaccines or continue with the same manufacturer.

If you received the one-dose Johnson & Johnson vaccine, you should get:

  • second vaccine dose of Pfizer or Moderna at least one month after your Johnson & Johnson vaccine 
  • An updated booster shot of Pfizer or Moderna at least two months after your second vaccine dose or most recent monovalent booster.

If you followed the CDC's previous booster guidelines for immunocompromised patients, this updated booster dose could be your fifth or sixth shot.

Free MUNI rides in San Francisco 

The San Francisco public transit agency is providing free MUNI and paratransit rides to and from COVID-19 vaccine appointments. The offer is good for trips to any vaccination site. You'll have to show your vaccination card or proof of your appointment (such as an email or text confirmation) when you board.

Public health recommendations for fully vaccinated people

See the latest COVID-19 recommendations from the CDC. Learn about your risks when it comes to socializing with vaccinated or unvaccinated people, other social activities outside the home, domestic and international travel, and more.