P. Daniel Knott, MD

Facial plastic, aesthetic and reconstructive surgeon

Dr. P. Daniel Knott is director of Facial Plastic, Aesthetic and Reconstructive Surgery in Otolaryngology-Head and Neck Surgery at UCSF Medical Center. Knott, who joined UCSF in 2011 after 10 years at the Cleveland Clinic, has training and experience in facial aesthetics and microvascular surgery. His expertise includes treatment of facial paralysis, facial rejuvenation, reconstruction of facial cutaneous malignancies, minimally invasive facial soft tissue augmentation, rhinoplasty and free tissue transfer.

In his research, he is helping develop new methods for palatal and orbito-maxillary reconstruction, microvascular treatment of osteonecrosis and cartilage bioengineering. He has won several national awards for his research, which includes studies of head and neck tissue transplantation. Knott earned a medical degree at the School of Medicine at the University of California, San Diego and completed a five-year surgical residency at the Cleveland Clinic in otolaryngology-head and neck surgery. He also completed a fellowship in facial plastic and reconstructive surgery at UCLA Medical Center. He is a professor of otolaryngology at UCSF.


Facial Plastic and Reconstructive Surgery
2320 Sutter St., Suite 102
San Francisco, CA 94115
Phone: (415) 353-9500
Fax: (415) 885-7785

Hours: Monday to Friday
8 a.m. – 5 p.m.

Head and Neck Surgery Cancer Clinic
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

Board Certification

Otolaryngology, American Board of Otolaryngology

Academic Title


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UC San Diego School of Medicine 2000


Cleveland Clinic Foundation Medical Center 2006


UCLA Medical Center 2007

Selected Research and Publications

  1. Likhterov I, Fritz MA, El-Sayed IH, Rayess HM, Knott PD. Locoregional recurrence following maxillectomy: implications for microvascular reconstruction. Laryngoscope. 2017 May 09.
  2. Alemi AS, Seth R, Heaton C, Wang SJ, Knott PD. Comparison of Video and In-person Free Flap Assessment following Head and Neck Free Tissue Transfer. Otolaryngol Head Neck Surg. 2017 Jun; 156(6):1035-1040.
  3. Tamplen ML, Tamplen J, Torrecillas V, Seth R, Ricceri S, Hemmat S, Heaton C, Ryan WR, Knott PD. Does a Standalone Cancer Center Improve Head and Neck Microsurgical Outcomes? J Reconstr Microsurg. 2017 May; 33(4):252-256.
  4. JŠuregui EJ, Tummala N, Seth R, Arron S, Neuhaus I, Yu S, Grekin R, Knott PD. Comparison of W-Plasty vs Traditional Straight-Line Techniques for Primary Paramedian Forehead Flap Donor Site Closure. JAMA Facial Plast Surg. 2016 Jul 01; 18(4):258-62.
  5. Tamplen M, Knott PD, Fritz MA, Seth R. Controversies in Parotid Defect Reconstruction. Facial Plast Surg Clin North Am. 2016 Aug; 24(3):235-43.
  6. Tamplen ML, Ricceri S, Hemmat S, Seth R, Ryan WR, Knott PD. Benefits of Immediate Extubation Following Free Tissue Transfer for Head and Neck Reconstruction. J Reconstr Microsurg. 2016 Sep; 32(7):533-9.
  7. Knott PD. A Facial Nerve Anniversary--Twelve Months of Treatment Time Saved. JAMA Facial Plast Surg. 2016 Jan-Feb; 18(1):60-1.
  8. Naunheim M, Seth R, Knott PD. Sternocleidomastoid contour restoration: an added benefit of the anterolateral thigh free flap during facial reconstruction. Am J Otolaryngol. 2016 Mar-Apr; 37(2):139-43.
  9. Xu X, Wilschut KJ, Kouklis G, Tian H, Hesse R, Garland C, Sbitany H, Hansen S, Seth R, Knott PD, Hoffman WY, Pomerantz JH. Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles. Stem Cell Reports. 2015 Sep 08; 5(3):419-34.
  10. Markey JD, Seth R, Wang SJ, Ryan WR, El-Sayed IH, Knott PD. Anterolateral Thigh Adipofascial Flap: A New Option for Scalp Reconstruction. J Reconstr Microsurg. 2016 Feb; 32(2):160-3.
  11. Markey J, Knott PD, Fritz MA, Seth R. Recent advances in head and neck free tissue transfer. Curr Opin Otolaryngol Head Neck Surg. 2015 Aug; 23(4):297-301.
  12. Knott PD, Seth R, Waters HH, Revenaugh PC, Alam D, Scharpf J, Meltzer NE, Fritz MA. Short-term donor site morbidity: A comparison of the anterolateral thigh and radial forearm fasciocutaneous free flaps. Head Neck. 2016 Apr; 38 Suppl 1:E945-8.
  13. Markey J, Seth R, Knott PD. Safety of cyanoacrylate-based adhesives in creating layered septal cartilage grafts during open structure septorhinoplasty. Am J Otolaryngol. 2015 Jul-Aug; 36(4):499-502.
  14. Revenaugh PC, Fritz MA, Haffey TM, Seth R, Markey J, Knott PD. Minimizing morbidity in microvascular surgery: small-caliber anastomotic vessels and minimal access approaches. JAMA Facial Plast Surg. 2015 Jan-Feb; 17(1):44-8.
  15. Kram YA, Russell MS, Russell MD, Knott PD. Single-stage, double-conduit microvascular pharyngotracheal reconstruction. J Reconstr Microsurg. 2015 Mar; 31(3):233-5.
  16. Cannady SB, Rosenthal EL, Knott PD, Fritz M, Wax MK. Free tissue transfer for head and neck reconstruction: a contemporary review. JAMA Facial Plast Surg. 2014 Sep-Oct; 16(5):367-73.
  17. Revenaugh PC, Knott PD, Alam DS, Kmiecik J, Fritz MA. Voice outcomes following reconstruction of laryngopharyngectomy defects using the radial forearm free flap and the anterolateral thigh free flap. Laryngoscope. 2014 Feb; 124(2):397-400.
  18. Revenaugh PC, Waters HH, Scharpf J, Knott PD, Fritz MA. Suprastomal cutaneous monitoring paddle for free flap reconstruction of laryngopharyngectomy defects. JAMA Facial Plast Surg. 2013 Jul-Aug; 15(4):287-91.
  19. Punthakee X, Zaghi S, Nabili V, Knott PD, Blackwell KE. Effects of salivary bypass tubes on fistula and stricture formation. JAMA Facial Plast Surg. 2013 May; 15(3):219-25.
  20. Rayess HM, Revenaugh PC, Benninger MS, Knott PD. Predictive factors for patient outcomes following open bedside tracheotomy. Laryngoscope. 2013 Apr; 123(4):923-8.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.