Donald Grandis, MD


Donald Grandis is a general cardiologist who has a particular interest in personalizing care to optimize cardiac disease prevention and management. He practices noninvasive cardiology, which includes transthoracic, stress and transesophageal echocardiography. Grandis also interprets stress tests and nuclear cardiac images. A professor at UCSF, his research focuses on the effects of air pollution on cardiovascular health and the use of remote-monitoring and other devices to improve health outcomes in patients with common heart conditions.

Grandis earned his medical degree from Virginia Commonwealth University School of Medicine and completed his medical internship, residency and cardiology fellowship at the University of Pittsburgh Medical Center.


Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Polycystic Kidney Disease (PKD) Center of Excellence
400 Parnassus Ave., B1 Plaza Level
San Francisco, CA 94143
Phone: (415) 514-2381

Hours: Monday to Friday,
9 a.m. - 5 p.m.

Board Certification

Cardiovascular Disease, American Board of Internal Medicine

Academic Title


More about Donald Grandis


Virginia Commonwealth University School of Medicine 1985


University of Pittsburgh Medical Center 1987


University of Pittsburgh Medical Center 1992

Selected Research and Publications

  1. Grandis DJ, Nah G, Whitman IR, Vittinghoff E, Dewland TA, Olgin JE, Marcus GM. Wilson's Disease and Cardiac Myopathy. Am J Cardiol. 2017 Dec 01; 120(11):2056-2060.
  2. Grandis DJ, MacGowan GA, Koretsky AP. Comparison of the effects of ORG 30029, dobutamine and high perfusate calcium on function and metabolism in rat heart. J Mol Cell Cardiol. 1998 Dec; 30(12):2605-12.
  3. Grandis DJ, DelNido PJ, Koretsky AP. Functional and energetic effects of the inotropic agents EMD-57033 and BAPTA on the isolated rat heart. Am J Physiol. 1995 Aug; 269(2 Pt 1):C472-9.
  4. Wolz DE, Flores AR, Grandis DJ, Orie JE, Schulman DS. Abnormal left ventricular ejection fraction response to mental stress and exercise in cardiomyopathy. J Nucl Cardiol. 1995 Mar-Apr; 2(2 Pt 1):144-50.
  5. Schulman DS, Grandis DJ, Deloplaine KA, Orie JE, Flores AR. Relationship between hemodynamics and right ventricular function in patients with cardiomyopathy. Important role of tricuspid regurgitation. Chest. 1995 Jan; 107(1):14-9.
  6. Detre JA, Zhang W, Roberts DA, Silva AC, Williams DS, Grandis DJ, Koretsky AP, Leigh JS. Tissue specific perfusion imaging using arterial spin labeling. NMR Biomed. 1994 Mar; 7(1-2):75-82.
  7. Lazar JM, Flores AR, Grandis DJ, Orie JE, Schulman DS. Effects of chronic right ventricular pressure overload on left ventricular diastolic function. Am J Cardiol. 1993 Nov 15; 72(15):1179-82.
  8. Schulman DS, Lazar JM, Ziady G, Grandis DJ, Flores AR, Orie JE. Right ventricular thallium-201 kinetics in pulmonary hypertension: relation to right ventricular size and function. J Nucl Med. 1993 Oct; 34(10):1695-700.
  9. Williams DS, Grandis DJ, Zhang W, Koretsky AP. Magnetic resonance imaging of perfusion in the isolated rat heart using spin inversion of arterial water. Magn Reson Med. 1993 Sep; 30(3):361-5.
  10. Grandis DJ, Uretsky BF, Verbalis JG, Chong TK, Puschett JB. Relationship of the renin-angiotensin system and systemic arterial pressure to sodium excretion during atrial natriuretic peptide infusion in men. Am J Hypertens. 1992 Nov; 5(11):793-9.
  11. Grandis DJ, Uretsky BF, Ray SM, Vassilaros L, Verbalis JG, Puschett JB. Differential effects of atrial natriuretic peptide infusion at physiological doses in different postures in humans. Am J Hypertens. 1991 Mar; 4(3 Pt 1):219-27.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.