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Heather Huddleston, M.D.

Fertility specialist

Dr. Heather Huddleston is an expert in reproductive endocrinology and fertility at the UCSF Center for Reproductive Health. She has a special interest in unexplained infertility, uterine disease and recurrent pregnancy loss. Huddleston is actively researching endometrial biology, recurrent miscarriage and ethnic differences in reproductive potential. She has spoken nationally on her research, which has been published in numerous medical and scientific journals.

Huddleston earned a medical degree at Harvard Medical School and completed an internship and residency in obstetrics and gynecology as well as a fellowship in reproductive endocrinology and infertility at Brigham and Women's Hospital and Massachusetts General Hospital in Boston. She is a member of the American College of Obstetrics and Gynecology and American Society for Reproductive Medicine. She is an adjunct assistant professor in reproductive endocrinology and infertility at UCSF.


Center for Reproductive Health at Mission Bay
499 Illinois St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-7475
Fax: (415) 353-7744

Hours: Monday to Friday
8 a.m. – 4:45 p.m.
Saturday and Sunday apts. available for patients undergoing treatment

Center for Reproductive Health at Mount Zion
2356 Sutter St., Seventh Floor
San Francisco, CA 94115
Phone: (415) 353-7475
Fax: (415) 353-7744

Hours: Monday to Friday
8 a.m. – 4:45 p.m.
Saturday and Sunday apts. available for patients undergoing treatment

PCOS Clinic
499 Illinois St.
San Francisco, CA 94158
Phone: (415) 885-3674
Fax: (415) 353-7744

Hours: Two Thursdays a month
8 a.m. – 5 p.m.

Conditions & Treatments

More about Heather Huddleston


Harvard School of Medicine 1998


Brigham and Women's Hospital, Obstetrics & Gynecology 2002


Brigham and Women's Hospital, Reproductive Endocrinology & Infertility 2005

Selected Research and Publications

  1. Greenwood EA, Pasch LA, Shinkai K, Cedars MI, Huddleston HG. Putative role for insulin resistance in depression risk in polycystic ovary syndrome. Fertil Steril. 2015 Sep; 104(3):707-714.e1.
  2. Leucht P, Huddleston HG, Bellino MJ, Huddleston JI. Does Intraoperative Fluoroscopy Optimize Limb Length and the Precision of Acetabular Positioning in Primary THA? Orthopedics. 2015 May 1; 38(5):e380-6.
  3. Kamangar F, Okhovat JP, Schmidt T, Beshay A, Pasch L, Cedars MI, Huddleston H, Shinkai K. Polycystic Ovary Syndrome: Special Diagnostic and Therapeutic Considerations for Children. Pediatr Dermatol. 2015 Sep; 32(5):571-8.
  4. Piltonen TT, Chen JC, Khatun M, Kangasniemi M, Liakka A, Spitzer T, Tran N, Huddleston H, Irwin JC, Giudice LC. Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro. Hum Reprod. 2015 May; 30(5):1203-15.
  5. Quinn M, Shinkai K, Pasch L, Kuzmich L, Cedars M, Huddleston H. Prevalence of androgenic alopecia in patients with polycystic ovary syndrome and characterization of associated clinical and biochemical features. Fertil Steril. 2014 Apr; 101(4):1129-34.
  6. Skillern AA, Cedars MI, Huddleston HG. Oocyte donors' comprehension as assessed by the EDICT (Egg Donor Informed Consent Tool). Fertil Steril. 2014 Jan; 101(1):248-51.
  7. Huddleston HG. Biomarkers of ovarian reserve in women with polycystic ovary syndrome. Semin Reprod Med. 2013 Nov; 31(6):452-61.
  8. Piltonen TT, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC. Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential. J Clin Endocrinol Metab. 2013 Sep; 98(9):3765-75.
  9. Wang ET, Kao CN, Shinkai K, Pasch L, Cedars MI, Huddleston HG. Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study. Fertil Steril. 2013 Jul; 100(1):214-8.
  10. Skillern A, Cedars M, Huddleston H. Egg Donor Informed Consent Tool (EDICT): development and validation of a new informed consent tool for oocyte donors. Fertil Steril. 2013 May; 99(6):1733-8.
  11. Foyouzi N, Cedars MI, Huddleston HG. Cost-effectiveness of cytogenetic evaluation of products of conception in the patient with a second pregnancy loss. Fertil Steril. 2012 Jul; 98(1):151-5.
  12. Mayle RE, Graw BP, Huddleston HG, Woolson ST, Goodman SB, Huddleston JI. MI TKA: a risk factor for early revision surgery. J Knee Surg. 2012 Nov; 25(5):423-7.
  13. Johnstone EB, Davis G, Zane LT, Cedars MI, Huddleston HG. Age-related differences in the reproductive and metabolic implications of polycystic ovarian syndrome: findings in an obese, United States population. Gynecol Endocrinol. 2012 Oct; 28(10):819-22.
  14. Koenig K, Huddleston JI, Huddleston H, Maloney WJ, Goodman SB. Advanced age and comorbidity increase the risk for adverse events after revision total hip arthroplasty. J Arthroplasty. 2012 Aug; 27(7):1402-1407.e1.
  15. Fujimoto VY, Bloom MS, Huddleston HG, Shelley WB, Ocque AJ, Browne RW. Correlations of follicular fluid oxidative stress biomarkers and enzyme activities with embryo morphology parameters during in vitro fertilization. Fertil Steril. 2011 Dec; 96(6):1357-61.
  16. Huddleston HG, Rosen MP, Gibson M, Cedars MI, Fujimoto VY. Ethnic variation in estradiol metabolism in reproductive age Asian and white women treated with transdermal estradiol. Fertil Steril. 2011 Sep; 96(3):797-9.
  17. Wang ET, Fujimoto VY, Yeaton-Massey AJ, Vittinghoff E, Caughey AB, Huddleston HG. Asian ethnicity and fecundability in women with spontaneous conceptions. Fertil Steril. 2011 Jun 30; 95(8):2769-71.
  18. Sharma H, Johnstone EB, Gates E, Sohn SH, Huddleston HG, Fujimoto VY. Asian immigrants to the United States are less likely to donate cryopreserved embryos for research use. Fertil Steril. 2011 Apr; 95(5):1672-6.
  19. Lamb JD, Johnstone EB, Rousseau JA, Jones CL, Pasch LA, Cedars MI, Huddleston HG. Physical activity in women with polycystic ovary syndrome: prevalence, predictors, and positive health associations. Am J Obstet Gynecol. 2011 Apr; 204(4):352.e1-6.
  20. Graw BP, Woolson ST, Huddleston HG, Goodman SB, Huddleston JI. Minimal incision surgery as a risk factor for early failure of total hip arthroplasty. Clin Orthop Relat Res. 2010 Sep; 468(9):2372-6.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.