Hubert Kim, PhD, MD

Orthopedic surgeon

Dr. Hubert Kim is director of the UCSF Cartilage Repair and Regeneration Center, located at the UCSF Orthopaedic Institute. Kim specializes in the treatment of arthritis and localized cartilage injuries of the knee, hip, shoulder and ankle. His research focuses on the mechanisms involved in cell death after articular cartilage injury and ways to limit this process. His lab also studies the use of mesenchymal stem cells for bone and cartilage repair as well as for muscle and nerve injuries.

Kim is a graduate of Stanford University and the Stanford University School of Medicine where he earned both M.D. and Ph.D. degrees. He completed a general surgery internship and orthopedic surgery residency at UCSF before joining the faculty in 1998.

Clinics

Arthritis and Joint Replacement Center
1500 Owens St., Suite 430
San Francisco, CA 94158
Phone: (415) 353–2808
Fax: (415) 885–3862

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Cartilage Repair and Regeneration Center
1500 Owens St.
San Francisco, CA 94158
Phone: (415) 353–7566

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

Board Certification

Orthopaedic Surgery, American Board of Orthopaedic Surgery

Academic Title

Professor

More about Hubert Kim

Education

Stanford University School of Medicine 1993

Residencies

UCSF, Orthopaedic Surgery 1998

Selected Research and Publications

  1. Liu X, Ravishankar B, Ning A, Liu M, Kim HT, Feeley BT. Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration. Muscles Ligaments Tendons J. 2017 Apr-Jun; 7(2):202-207.
  2. Davies MR, Lee L, Feeley BT, Kim HT, Liu X. Lysophosphatidic acid-induced RhoA signaling and prolonged macrophage infiltration worsens fibrosis and fatty infiltration following rotator cuff tears. J Orthop Res. 2017 07; 35(7):1539-1547.
  3. Davies MR, Liu X, Lee L, Laron D, Ning AY, Kim HT, Feeley BT. TGF- Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis. PLoS One. 2016; 11(5):e0155486.
  4. Bahney CS, Jacobs L, Tamai R, Hu D, Luan TF, Wang M, Reddy S, Park M, Limburg S, Kim HT, Marcucio R, Kuo AC. Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes. Tissue Eng Part A. 2016 Mar; 22(5-6):427-35.
  5. Krigbaum H, Takemoto S, Kim HT, Kuo AC. Costs and Complications of Short Versus Long Cephalomedullary Nailing of OTA 31-A2 Proximal Femur Fractures in U.S. Veterans. J Orthop Trauma. 2016 Mar; 30(3):125-9.
  6. Joshi SK, Lee L, Lovett DH, Kang H, Kim HT, Delgado C, Liu X. Novel intracellular N-terminal truncated matrix metalloproteinase-2 isoform in skeletal muscle ischemia-reperfusion injury. J Orthop Res. 2016 Mar; 34(3):502-9.
  7. Liu X, Joshi S, Ravishankar B, Laron D, Kim HT, Feeley BT. Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration. Muscles Ligaments Tendons J. 2015 Apr-Jun; 5(2):113-9.
  8. Ward DT, Metz LN, Horst PK, Kim HT, Kuo AC. Complications of Morbid Obesity in Total Joint Arthroplasty: Risk Stratification Based on BMI. J Arthroplasty. 2015 Sep; 30(9 Suppl):42-6.
  9. Davies MR, Ravishankar B, Laron D, Kim HT, Liu X, Feeley BT. Rat rotator cuff muscle responds differently from hindlimb muscle to a combined tendon-nerve injury. J Orthop Res. 2015 Jul; 33(7):1046-53.
  10. Zhang Q, Joshi SK, Lovett DH, Zhang B, Bodine S, Kim HT, Liu X. Matrix metalloproteinase-2 plays a critical role in overload induced skeletal muscle hypertrophy. Muscles Ligaments Tendons J. 2014 Oct-Dec; 4(4):446-54.
  11. Liu X, Joshi SK, Ravishankar B, Laron D, Kim HT, Feeley BT. Upregulation of transforming growth factor- signaling in a rat model of rotator cuff tears. J Shoulder Elbow Surg. 2014 Nov; 23(11):1709-16.
  12. Kang H, Dang AB, Joshi SK, Halloran B, Nissenson R, Zhang X, Li J, Kim HT, Liu X. Novel mouse model of spinal cord injury-induced heterotopic ossification. J Rehabil Res Dev. 2014; 51(7):1109-18.
  13. Onur TS, Wu R, Chu S, Chang W, Kim HT, Dang AB. Joint instability and cartilage compression in a mouse model of posttraumatic osteoarthritis. J Orthop Res. 2014 Feb; 32(2):318-23.
  14. Joshi SK, Kim HT, Feeley BT, Liu X. Differential ubiquitin-proteasome and autophagy signaling following rotator cuff tears and suprascapular nerve injury. J Orthop Res. 2014 Jan; 32(1):138-44.
  15. Wang M, Rahnama R, Cheng T, Grotkopp E, Jacobs L, Limburg S, Kim HT, Kuo AC. Trophic stimulation of articular chondrocytes by late-passage mesenchymal stem cells in coculture. J Orthop Res. 2013 Dec; 31(12):1936-42.
  16. Jin J, Limburg S, Joshi SK, Landman R, Park M, Zhang Q, Kim HT, Kuo AC. Peripheral nerve repair in rats using composite hydrogel-filled aligned nanofiber conduits with incorporated nerve growth factor. Tissue Eng Part A. 2013 Oct; 19(19-20):2138-46.
  17. Zhang Q, Joshi SK, Manzano G, Lovett DH, Kim HT, Liu X. Original article Muscle extracellular matrix degradation and contractibility following tendon rupture and disuse. Muscles Ligaments Tendons J. 2013 Jan; 3(1):35-41.
  18. Kramer EJ, Bodendorfer BM, Laron D, Wong J, Kim HT, Liu X, Feeley BT. Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy. J Shoulder Elbow Surg. 2013 Dec; 22(12):1702-9.
  19. Rahnama R, Wang M, Dang AC, Kim HT, Kuo AC. Cytotoxicity of local anesthetics on human mesenchymal stem cells. J Bone Joint Surg Am. 2013 Jan 16; 95(2):132-7.
  20. Joshi SK, Liu X, Samagh SP, Lovett DH, Bodine SC, Kim HT, Feeley BT. mTOR regulates fatty infiltration through SREBP-1 and PPAR? after a combined massive rotator cuff tear and suprascapular nerve injury in rats. J Orthop Res. 2013 May; 31(5):724-30.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.