Andrew Krystal



About me

Dr. Andrew Krystal is a psychiatrist who cares for adults with all types of sleep disorders, with particular expertise in insomnia. He also treats patients who have mood and anxiety spectrum disorders in addition to sleep disorders. An internationally renowned expert on sleep and mood disorders, he has more than 25 years of experience in patient care and research.

Krystal's research focuses on understanding insomnia's causes and how insomnia may be related to psychiatric or other medical conditions. He also studies new treatments for insomnia and other sleep disorders, as well as how sleep maintains and restores normal human functions.

After completing a master's degree in biomedical engineering at the Massachusetts Institute of Technology, Krystal earned his medical degree at Duke University School of Medicine. He then completed a residency in psychiatry at Duke, followed by fellowships in sleep medicine and clinical neurophysiology (studying the nervous system through recording the body's electrical activity). In addition to holding various leadership positions, he served as a faculty member and physician at Duke Health for more than two decades before joining UCSF in 2016.

Krystal is president of the Sleep Research Society and a member of the American Academy of Sleep Medicine, American Psychiatric Association and American College of Neuropsychopharmacology. He serves on the examination committee of the American Board of Sleep Medicine, which allows medical professionals to pursue certification in sleep medicine.

  • Education

    Duke University School of Medicine, 1987

    MIT, MS, Biomedical Engineering, 1983

  • Residencies

    Duke University, Psychiatry, 1991

  • Fellowship

    Duke University, Sleep Medicine and Clinical Neurophysiology, 1993

  • Board Certifications

    Psychiatry, American Board of Psychiatry and Neurology

  • Academic Title


Neuro/Psych Sleep Clinic

400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143

Decorative Caduceus

Closed-Loop Deep Brain Stimulation for Major Depression

Neurons are specialized types of cells that are responsible for carrying out the functions of the brain. Neurons communicate with electrical signals. In diseases such as major depression this electrical communication...


Decorative Caduceus

Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

Obstructive sleep apnea (OSA) is a common condition associated with significant adverse health outcomes. Our overarching hypothesis is that patients with OSA and hypoxia (H-OSA) have greater degrees of insulin resist...


Decorative Caduceus

Transcranial Direct Current Stimulation (tDCS) as a Treatment for Acute Fear

Locus coeruleus (LC) norepinephrine (NE) neuron activity has been convincingly linked to regulation of acute fear. This study will address whether LC NE activity examined through pupil measures will reflect carbon di...


Providers on my team