Ruby Ghadially, MD



Psoriasis and Skin Treatment Center
515 Spruce St.
San Francisco, CA 94118
Phone: (415) 476-4701
Fax: (415) 502-4126

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

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University of Sheffield England 1982


University of Toronto, Dermatology 1988

Selected Research and Publications

  1. Charruyer A, Fong S, Vitcov GG, Sklar S, Tabernik L, Taneja M, Caputo M, Soeung C, Yue L, Uchida Y, Arron ST, Horton KM, Foster RD, Sano S, North JP, Ghadially R. Brief Report: Interleukin-17A-Dependent Asymmetric Stem Cell Divisions Are Increased in Human Psoriasis: A Mechanism Underlying Benign Hyperproliferation. Stem Cells. 2017 Aug; 35(8):2001-2007.
  2. Ghadially R, Marcus P. Feroze N. Ghadially - Polymath Extraordinaire. Ultrastruct Pathol. 2017 Jan-Feb; 41(1):68.
  3. Charruyer A, Fong S, Yue L, Arron ST, Ghadially R. Phycosaccharide AI, a mixture of alginate polysaccharides, increases stem cell proliferation in aged keratinocytes. Exp Dermatol. 2016 Sep; 25(9):738-40.
  4. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48.
  5. Szabo AZ, Fong S, Yue L, Zhang K, Strachan LR, Scalapino K, Mancianti ML, Ghadially R. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells. 2013 Apr; 31(4):786-99.
  6. Charruyer A, Strachan LR, Yue L, Toth AS, Cecchini G, Mancianti ML, Ghadially R. CD133 is a marker for long-term repopulating murine epidermal stem cells. J Invest Dermatol. 2012 Nov; 132(11):2522-33.
  7. Ghadially R. 25 years of epidermal stem cell research. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):797-810.
  8. Ghadially R. The role of stem and circulating cells in cancer metastasis. J Surg Oncol. 2011 May 01; 103(6):555-7.
  9. Charruyer A, Ghadially R. What's new in dermatology: epidermal stem cells. G Ital Dermatol Venereol. 2011 Feb; 146(1):57-67.
  10. Boonyaratanakornkit JB, Yue L, Strachan LR, Scalapino KJ, LeBoit PE, Lu Y, Leong SP, Smith JE, Ghadially R. Selection of tumorigenic melanoma cells using ALDH. J Invest Dermatol. 2010 Dec; 130(12):2799-808.
  11. Strachan LR, Ghadially R. Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay. Methods Mol Biol. 2010; 585:421-32.
  12. Charruyer A, Barland CO, Yue L, Wessendorf HB, Lu Y, Lawrence HJ, Mancianti ML, Ghadially R. Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis. J Invest Dermatol. 2009 Nov; 129(11):2574-83.
  13. Charruyer A, Ghadially R. Stem cells and tissue-engineered skin. Skin Pharmacol Physiol. 2009; 22(2):55-62.
  14. Strachan LR, Ghadially R. Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited. Stem Cell Rev. 2008 Sep; 4(3):149-57.
  15. Strachan LR, Scalapino KJ, Lawrence HJ, Ghadially R. Rapid adhesion to collagen isolates murine keratinocytes with limited long-term repopulating ability in vivo despite high clonogenicity in vitro. Stem Cells. 2008 Jan; 26(1):235-43.
  16. Silvander M, Ringstad L, Ghadially R, Sköld T. A new water-based topical carrier with polar skin-lipids. Lipids Health Dis. 2006 May 03; 5:12.
  17. Ghadially R. Epidermal stem cells. Adv Dermatol. 2005; 21:335-55.
  18. Ghadially R. In search of the elusive epidermal stem cell. Ernst Schering Res Found Workshop. 2005; (54):45-62.
  19. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004 Feb; 122(2):330-6.
  20. Schneider TE, Barland C, Alex AM, Mancianti ML, Lu Y, Cleaver JE, Lawrence HJ, Ghadially R. Measuring stem cell frequency in epidermis: a quantitative in vivo functional assay for long-term repopulating cells. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11412-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.