Theodore Abraham, MD

Cardiologist
Co-director, UCSF HCM Center of Excellence
Director, UCSF Adult Cardiac Echocardiography Laboratory

Dr. Theodore Abraham is a cardiologist who treats adults with hypertrophic cardiomyopathy (HCM), a condition that causes heart muscle to thicken so that the heart has to work harder than it should. HCM often goes undiagnosed and is usually inherited, so Abraham has a particular interest in evaluating people with suspected HCM and family members of patients with the condition.

Abraham employs various types of heart imaging to discern whether athletes whose hearts appear abnormal on diagnostic images have an underlying heart problem or are actually normal. He also uses strain echocardiography — a method of measuring deformed heart muscle — for early diagnosis, monitoring disease progression and predicting a variety of cardiac diseases, particularly those of the heart muscle and those affecting athletes.

Abraham directs the UCSF Adult Cardiac Echocardiography Lab at the Parnassus campus and co-directs the UCSF HCM Center of Excellence.

Before joining UCSF as a professor of clinical medicine in 2017, he was a professor of medicine, radiology and radiological science at Johns Hopkins Medicine, where he also served as associate dean for research. Abraham's research on HCM focuses on early diagnosis as well as risk prediction.

Abraham earned his medical degree from the University of Mumbai. He then completed a residency in internal medicine at Wake Forest School of Medicine, where he also completed a research fellowship in echocardiography. He completed additional fellowships in clinical cardiology at the University of Texas Southwestern Medical Center and advanced echocardiography at the Mayo Clinic in Rochester, Minnesota.

Abraham is a fellow of the American College of Cardiology and American Society of Echocardiography. He is a member of the American Heart Association, where he serves on the Council on Clinical Cardiology and Council on Basic Cardiovascular Sciences. The recipient of numerous research grants and awards in his field, he is on the editorial boards of the Journal of the American Society of Echocardiography, Journal of the American College of Cardiology: Cardiovascular Imaging and Circulation: Cardiovascular Imaging, a journal of the American Heart Association. He also serves as an expert on HCM for the British Medical Journal.

Clinics

Echocardiography Lab at Parnassus
505 Parnassus Ave., Suite M344
San Francisco, CA 94143
Phone: (415) 353-1262
Fax: (415) 353-1784

Hours: Monday to Friday
8:30 a.m. – 5 p.m.

Conditions & Treatments

  • Hypertrophic Cardiomyopathy

Board Certification

Cardiovascular Disease, American Board of Internal Medicine

Academic Title

Professor

More about Theodore Abraham

Education

University of Mumbai 1991

Residencies

Wake Forest School of Medicine, Internal Medicine 1995

Fellowships

Wake Forest School of Medicine, Echocardiography 1996
University of Texas Southwestern Medical Center, Clinical Cardiology 1999
Mayo Clinic, Advanced Echocardiography 2001

Selected Research and Publications

  1. Badano LP, Kolias TJ, Muraru D, Abraham TP, Aurigemma G, Edvardsen T, D'Hooge J, Donal E, Fraser AG, Marwick T, Mertens L, Popescu BA, Sengupta PP, Lancellotti P, Thomas JD, Voigt JU. Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J Cardiovasc Imaging. 2018 Mar 27.
  2. Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR. Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 2018 Mar 22; 3(6).
  3. Lu DY, Pozios I, Haileselassie B, Ventoulis I, Liu H, Sorensen LL, Canepa M, Phillip S, Abraham MR, Abraham TP. Clinical Outcomes in Patients With Nonobstructive, Labile, and Obstructive Hypertrophic Cardiomyopathy. J Am Heart Assoc. 2018 Feb 25; 7(5).
  4. Yalcin H, Valenta I, Zhao M, Tahari A, Lu DY, Higuchi T, Yalcin F, Kucukler N, Soleimanifard Y, Zhou Y, Pomper MG, Abraham TP, Tsui B, Lodge MA, Schindler TH, Abraham MR. Correction to: Comparison of two software systems for quantification of myocardial blood flow in patients with hypertrophic cardiomyopathy. J Nucl Cardiol. 2018 Feb 08.
  5. Pozios I, Pinheiro A, Corona-Villalobos C, Sorensen LL, Dardari Z, Liu HY, Cresswell K, Phillip S, Bluemke DA, Zimmerman SL, Abraham MR, Abraham TP. Rest and Stress Longitudinal Systolic Left Ventricular Mechanics in Hypertrophic Cardiomyopathy: Implications for Prognostication. J Am Soc Echocardiogr. 2018 Feb 06.
  6. Yalcin H, Valenta I, Zhao M, Tahari A, Lu DY, Higuchi T, Yalcin F, Kucukler N, Soleimanifard Y, Zhou Y, Pomper MG, Abraham TP, Tsui B, Lodge MA, Schindler TH, Roselle Abraham M. Comparison of two software systems for quantification of myocardial blood flow in patients with hypertrophic cardiomyopathy. J Nucl Cardiol. 2018 Jan 22.
  7. Yalcin F, Kucukler N, Cingolani OH, Mbiyangandu B, Sorensen L, Pinherio A, Abraham R, Abraham TP. Evolution of Ventricular Hypertrophy and Myocardial Mechanics in Physiologic and Pathologic Hypertrophy. J Appl Physiol (1985). 2018 Jan 04.
  8. Lu DY, Haileselassie B, Ventoulis I, Liu HY, Liang HY, Pozios I, Canepa M, Phillip S, Abraham MR, Abraham T. E/e' ratio and outcome prediction in hypertrophic cardiomyopathy: the influence of outflow tract obstruction. Eur Heart J Cardiovasc Imaging. 2018 Jan 01; 19(1):101-107.
  9. Lu DY, Hailesealassie B, Ventoulis I, Liu H, Liang HY, Nowbar A, Pozios I, Canepa M, Cresswell K, Luo HC, Abraham MR, Abraham TP. Impact of peak provoked left ventricular outflow tract gradients on clinical outcomes in hypertrophic cardiomyopathy. Int J Cardiol. 2017 Sep 15; 243:290-295.
  10. Chu LC, Corona-Villalobos CP, Halushka MK, Zhang Y, Pozzessere C, Kamel IR, Pozios I, Van Der Geest RJ, Gai N, Abraham RM, Abraham TP, Bluemke DA, Zimmerman SL. Structural and Functional Correlates of Myocardial T1 Mapping in 321 Patients With Hypertrophic Cardiomyopathy. J Comput Assist Tomogr. 2017 Jul/Aug; 41(4):653-660.
  11. Liu H, Pozios I, Haileselassie B, Nowbar A, Sorensen LL, Phillip S, Lu DY, Ventoulis I, Luo H, Abraham MR, Abraham TP. Role of Global Longitudinal Strain in Predicting Outcomes in Hypertrophic Cardiomyopathy. Am J Cardiol. 2017 Aug 15; 120(4):670-675.
  12. Lu DY, Abraham TP. A Good Heart Is Hard to Find: Even Early in Hypertrophic Cardiomyopathy. Circ Cardiovasc Imaging. 2017 May; 10(5).
  13. Haileselassie B, Su E, Pozios I, Niño DF, Liu H, Lu DY, Ventoulis I, Fulton WB, Sodhi CP, Hackam D, O'Rourke B, Abraham T. Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis. Intensive Care Med Exp. 2017 Dec; 5(1):21.
  14. Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ. The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study. JAMA Cardiol. 2017 Apr 01; 2(4):419-428.
  15. Mast TP, James CA, Calkins H, Teske AJ, Tichnell C, Murray B, Loh P, Russell SD, Velthuis BK, Judge DP, Dooijes D, Tedford RJ, van der Heijden JF, Tandri H, Hauer RN, Abraham TP, Doevendans PA, Te Riele AS, Cramer MJ. Evaluation of Structural Progression in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. JAMA Cardiol. 2017 Mar 01; 2(3):293-302.
  16. Canepa M, Vianello PF, Abraham TP. T1 mapping with cardiovascular magnetic resonance: an emerging clinical biomarker. Heart. 2017 02 15; 103(4):326.
  17. Corona-Villalobos CP, Saha S, Pozios I, Hurtado-de-Mendoza Paz D, Sorensen L, Gonzalez Cordoba J, Dolores-Cerna K, Kamel IR, Mormontoy Laurel W, Bluemke DA, Abraham TP, Zimmerman SL, Abraham MR. Exercise-QTc is associated with diffuse interstitial fibrosis reflected by lower approximated T1 relaxation time in hypertrophic cardiomyopathy patients. J Electrocardiol. 2017 Jul - Aug; 50(4):484-490.
  18. Hurtado-de-Mendoza D, Corona-Villalobos CP, Pozios I, Gonzales J, Soleimanifard Y, Sivalokanathan S, Montoya-Cerrillo D, Vakrou S, Kamel I, Mormontoy-Laurel W, Dolores-Cerna K, Suarez J, Perez-Melo S, Bluemke DA, Abraham TP, Zimmerman SL, Abraham MR. Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy. J Arrhythm. 2017 Jun; 33(3):201-207.
  19. Chu LC, Porter KK, Corona-Villalobos CP, Gülsün MA, Shea SM, Markl M, Abraham TP, Bluemke DA, Kamel IR, Zimmerman SL. Evaluation of Left Ventricular Outflow Tract Obstruction With Four-Dimensional Phase Contrast Magnetic Resonance Imaging in Patients with Hypertrophic Cardiomyopathy-A Pilot Study. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):937-940.
  20. Harfi TT, Seo JH, Yasir HS, Welsh N, Mayer SA, Abraham TP, George RT, Mittal R. The E-wave propagation index (EPI): A novel echocardiographic parameter for prediction of left ventricular thrombus. Derivation from computational fluid dynamic modeling and validation on human subjects. Int J Cardiol. 2017 Jan 15; 227:662-667.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.