Theodore Abraham, MD

Cardiologist
Co-director, UCSF HCM Center of Excellence
Director, UCSF Adult Cardiac Echocardiography Laboratory

Dr. Theodore Abraham is a cardiologist who treats adults with hypertrophic cardiomyopathy (HCM), a condition that causes heart muscle to thicken so that the heart has to work harder than it should. HCM often goes undiagnosed and is usually inherited, so Abraham has a particular interest in evaluating people with suspected HCM and family members of patients with the condition.

Abraham employs various types of heart imaging to discern whether athletes whose hearts appear abnormal on diagnostic images have an underlying heart problem or are actually normal. He also uses strain echocardiography — a method of measuring deformed heart muscle — for early diagnosis, monitoring disease progression and predicting a variety of cardiac diseases, particularly those of the heart muscle and those affecting athletes.

Abraham directs the UCSF Adult Cardiac Echocardiography Lab at the Parnassus campus and co-directs the UCSF HCM Center of Excellence.

Before joining UCSF as a professor of clinical medicine in 2017, he was a professor of medicine, radiology and radiological science at Johns Hopkins Medicine, where he also served as associate dean for research. Abraham's research on HCM focuses on early diagnosis as well as risk prediction.

Abraham earned his medical degree from the University of Mumbai. He then completed a residency in internal medicine at Wake Forest School of Medicine, where he also completed a research fellowship in echocardiography. He completed additional fellowships in clinical cardiology at the University of Texas Southwestern Medical Center and advanced echocardiography at the Mayo Clinic in Rochester, Minnesota.

Abraham is a fellow of the American College of Cardiology and American Society of Echocardiography. He is a member of the American Heart Association, where he serves on the Council on Clinical Cardiology and Council on Basic Cardiovascular Sciences. The recipient of numerous research grants and awards in his field, he is on the editorial boards of the Journal of the American Society of Echocardiography, Journal of the American College of Cardiology: Cardiovascular Imaging and Circulation: Cardiovascular Imaging, a journal of the American Heart Association. He also serves as an expert on HCM for the British Medical Journal.

Clinics

Echocardiography Lab at Parnassus
505 Parnassus Ave., Suite M344
San Francisco, CA 94143
Phone: (415) 353-1262
Fax: (415) 353-1784

Hours: Monday to Friday
8:30 a.m. – 5 p.m.

Conditions & Treatments

  • Hypertrophic Cardiomyopathy

Board Certification

Cardiovascular Disease, American Board of Internal Medicine

Academic Title

Professor

More about Theodore Abraham

Education

University of Mumbai 1991

Residencies

Wake Forest School of Medicine, Internal Medicine 1995

Fellowships

Wake Forest School of Medicine, Echocardiography 1996
University of Texas Southwestern Medical Center, Clinical Cardiology 1999
Mayo Clinic, Advanced Echocardiography 2001

Selected Research and Publications

  1. Chu LC, Corona-Villalobos CP, Halushka MK, Zhang Y, Pozzessere C, Kamel IR, Pozios I, Van Der Geest RJ, Gai N, Abraham RM, Abraham TP, Bluemke DA, Zimmerman SL. Structural and Functional Correlates of Myocardial T1 Mapping in 321 Patients With Hypertrophic Cardiomyopathy. J Comput Assist Tomogr. 2017 Jul/Aug; 41(4):653-660.
  2. Liu H, Pozios I, Haileselassie B, Nowbar A, Sorensen LL, Phillip S, Lu DY, Ventoulis I, Luo H, Abraham MR, Abraham TP. Role of Global Longitudinal Strain in Predicting Outcomes in Hypertrophic Cardiomyopathy. Am J Cardiol. 2017 Aug 15; 120(4):670-675.
  3. Lu DY, Abraham TP. A Good Heart Is Hard to Find: Even Early in Hypertrophic Cardiomyopathy. Circ Cardiovasc Imaging. 2017 May; 10(5).
  4. Haileselassie B, Su E, Pozios I, Niño DF, Liu H, Lu DY, Ventoulis I, Fulton WB, Sodhi CP, Hackam D, O'Rourke B, Abraham T. Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis. Intensive Care Med Exp. 2017 Dec; 5(1):21.
  5. Mast TP, James CA, Calkins H, Teske AJ, Tichnell C, Murray B, Loh P, Russell SD, Velthuis BK, Judge DP, Dooijes D, Tedford RJ, van der Heijden JF, Tandri H, Hauer RN, Abraham TP, Doevendans PA, Te Riele AS, Cramer MJ. Evaluation of Structural Progression in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. JAMA Cardiol. 2017 Mar 01; 2(3):293-302.
  6. Canepa M, Vianello PF, Abraham TP. T1 mapping with cardiovascular magnetic resonance: an emerging clinical biomarker. Heart. 2017 Feb 15; 103(4):326.
  7. Corona-Villalobos CP, Saha S, Pozios I, Hurtado-de-Mendoza Paz D, Sorensen L, Gonzalez Cordoba J, Dolores-Cerna K, Kamel IR, Mormontoy Laurel W, Bluemke DA, Abraham TP, Zimmerman SL, Abraham MR. Exercise-QTc is associated with diffuse interstitial fibrosis reflected by lower approximated T1 relaxation time in hypertrophic cardiomyopathy patients. J Electrocardiol. 2017 Jul - Aug; 50(4):484-490.
  8. Hurtado-de-Mendoza D, Corona-Villalobos CP, Pozios I, Gonzales J, Soleimanifard Y, Sivalokanathan S, Montoya-Cerrillo D, Vakrou S, Kamel I, Mormontoy-Laurel W, Dolores-Cerna K, Suarez J, Perez-Melo S, Bluemke DA, Abraham TP, Zimmerman SL, Abraham MR. Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy. J Arrhythm. 2017 Jun; 33(3):201-207.
  9. Chu LC, Porter KK, Corona-Villalobos CP, Gülsün MA, Shea SM, Markl M, Abraham TP, Bluemke DA, Kamel IR, Zimmerman SL. Evaluation of Left Ventricular Outflow Tract Obstruction With Four-Dimensional Phase Contrast Magnetic Resonance Imaging in Patients with Hypertrophic Cardiomyopathy-A Pilot Study. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):937-940.
  10. Harfi TT, Seo JH, Yasir HS, Welsh N, Mayer SA, Abraham TP, George RT, Mittal R. The E-wave propagation index (EPI): A novel echocardiographic parameter for prediction of left ventricular thrombus. Derivation from computational fluid dynamic modeling and validation on human subjects. Int J Cardiol. 2017 Jan 15; 227:662-667.
  11. Sorensen LL, Liang HY, Pinheiro A, Hilser A, Dimaano V, Olsen NT, Hansen TF, Sogaard P, Nowbar A, Pisanello C, Pozios I, Phillip S, Zhou X, Abraham R, Abraham TP. Safety profile and utility of treadmill exercise in patients with high-gradient hypertrophic cardiomyopathy. Am Heart J. 2017 Feb; 184:47-54.
  12. Yalçin H, Valenta I, Yalçin F, Corona-Villalobos C, Vasquez N, Ra J, Kucukler N, Tahari A, Pozios I, Zhou Y, Pomper M, Abraham TP, Schindler TH, Abraham MR. Effect of Diffuse Subendocardial Hypoperfusion on Left Ventricular Cavity Size by 13N-Ammonia Perfusion PET in Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2016 Dec 15; 118(12):1908-1915.
  13. Pozios I, Abraham TP. Nonobstructive Hypertrophic Cardiomyopathy: Low Mortality but Not Always Benign. J Am Coll Cardiol. 2016 Aug 30; 68(9):982-3.
  14. Haileselassie B, Su E, Thompson R, Abraham T. The authors reply. Pediatr Crit Care Med. 2016 Aug; 17(8):812-3.
  15. Mukherjee M, Chung SE, Ton VK, Tedford RJ, Hummers LK, Wigley FM, Abraham TP, Shah AA. Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients. Circ Cardiovasc Imaging. 2016 Jun; 9(6).
  16. Lin X, Steinberg S, Kandasamy SK, Afzal J, Mbiyangandu B, Liao SE, Guan Y, Corona-Villalobos CP, Matkovich SJ, Epstein N, Tripodi D, Huo Z, Cutting G, Abraham TP, Fukunaga R, Abraham MR. Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis. PLoS One. 2016; 11(5):e0156065.
  17. Haileselassie B, Su E, Pozios I, Fiskum T, Thompson R, Abraham T. Strain Echocardiography Parameters Correlate With Disease Severity in Children and Infants With Sepsis. Pediatr Crit Care Med. 2016 05; 17(5):383-90.
  18. Sorensen LL, Pinheiro A, Dimaano VL, Pozios I, Nowbar A, Liu H, Luo HC, Lin X, Olsen NT, Hansen TF, Sogaard P, Abraham MR, Abraham TP. Comparison of Clinical Features in Blacks Versus Whites With Hypertrophic Cardiomyopathy. Am J Cardiol. 2016 Jun 01; 117(11):1815-20.
  19. Corona-Villalobos CP, Sorensen LL, Pozios I, Chu L, Eng J, Abraham MR, Abraham TP, Kamel IR, Zimmerman SL. Left ventricular wall thickness in patients with hypertrophic cardiomyopathy: a comparison between cardiac magnetic resonance imaging and echocardiography. Int J Cardiovasc Imaging. 2016 Jun; 32(6):945-54.
  20. Sĝrensen LL, Bedja D, Sysa-Shah P, Liu H, Maxwell A, Yi X, Pozios I, Olsen NT, Abraham TP, Abraham R, Gabrielson K. Echocardiographic Characterization of a Murine Model of Hypertrophic Obstructive Cardiomyopathy Induced by Cardiac-specific Overexpression of Epidermal Growth Factor Receptor 2. Comp Med. 2016; 66(4):268-77.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.