Yerem Yeghiazarians, MD

Interventional cardiologist

Dr. Yerem Yeghiazarians is co-director of the Adult Cardiac Catheterization Laboratory, director of the Peripheral Interventional Cardiology Program and director of the UCSF Translational Cardiac Stem Cell Program. He is an expert in managing patients with coronary artery disease, acute coronary syndromes, valvular heart disease, cardiomyopathies, patent foramen ovale and peripheral arterial diseases.

Yeghiazarians earned an undergraduate degree from Brandeis University and a medical degree from the Johns Hopkins School of Medicine. He trained in internal medicine at Brigham and Women's Hospital, a teaching affiliate of Harvard Medical School, where he was chief medical resident and an instructor in medicine. He also completed general and interventional adult cardiology training at Brigham and Women's Hospital. At UCSF, he is a professor of cardiology.

Clinics

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Heart Valve Disease Clinic
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday through Friday, 8 a.m. – 5 p.m.

HHT Center of Excellence
185 Berry St., Suite 180, Lobby 6
San Francisco, CA 94107
Phone: (415) 353-8867
Fax: (415) 353-4503

Hours: Monday to Friday,
8 a.m. – 4:30 p.m.

Conditions & Treatments

Board Certification

Cardiovascular Disease, American Board of Internal Medicine
Interventional Cardiology, American Board of Internal Medicine

Academic Title

Professor

More about Yerem Yeghiazarians

Additional Languages

Armenian
French
Persian

Education

Johns Hopkins University School of Medicine 1995

Residencies

Brigham and Women's Hospital-Harvard Medical School, Internal Medicine 1998

Fellowships

Brigham and Women's Hospital-Harvard Medical School, Cardiology 2003

Selected Research and Publications

  1. Browne S, Jha AK, Ameri K, Marcus SG, Yeghiazarians Y, Healy KE. TGF-1/CD105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels. PLoS One. 2018; 13(3):e0194679.
  2. Geng X, Hwang J, Ye J, Shih H, Coulter B, Naudin C, Jun K, Sievers R, Yeghiazarians Y, Lee RJ, Boyle AJ. Aging is protective against pressure overload cardiomyopathy via adaptive extracellular matrix remodeling. Am J Cardiovasc Dis. 2017; 7(3):72-82.
  3. Ameri K, Samurkashian R, Yeghiazarians Y. Three-Dimensional Bioprinting: Emerging Technology in Cardiovascular Medicine. Circulation. 2017 Apr 04; 135(14):1281-1283.
  4. Kallianos K, Henry TS, Yeghiazarians Y, Zimmet J, Shunk KA, Tseng EE, Mahadevan V, Hope MD. Ferumoxytol MRA for transcatheter aortic valve replacement planning with renal insufficiency. Int J Cardiol. 2017 Mar 15; 231:255-257.
  5. Jha AK, Tharp KM, Browne S, Ye J, Stahl A, Yeghiazarians Y, Healy KE. Matrix metalloproteinase-13 mediated degradation of hyaluronic acid-based matrices orchestrates stem cell engraftment through vascular integration. Biomaterials. 2016 May; 89:136-47.
  6. Chen Q, Varga M, Wang X, Haddad DJ, An S, Medzikovic L, Derakhshandeh R, Kostyushev DS, Zhang Y, Clifford BT, Luu E, Danforth OM, Rafikov R, Gong W, Black SM, Suchkov SV, Fineman JR, Heiss C, Aschbacher K, Yeghiazarians Y, Springer ML. Overexpression of Nitric Oxide Synthase Restores Circulating Angiogenic Cell Function in Patients With Coronary Artery Disease: Implications for Autologous Cell Therapy for Myocardial Infarction. J Am Heart Assoc. 2016 Jan 06; 5(1).
  7. Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol. 2017 Feb; 24(1):268-277.
  8. Ye J, Yeghiazarians Y. Cardiac stem cell therapy: Have we put too much hype in which cell type to use? Heart Fail Rev. 2015 Sep; 20(5):613-9.
  9. Ye J, Gaur M, Zhang Y, Sievers RE, Woods BJ, Aurigui J, Bernstein HS, Yeghiazarians Y. Treatment with hESC-Derived Myocardial Precursors Improves Cardiac Function after a Myocardial Infarction. PLoS One. 2015; 10(7):e0131123.
  10. Genet M, Chuan Lee L, Ge L, Acevedo-Bolton G, Jeung N, Martin A, Cambronero N, Boyle A, Yeghiazarians Y, Kozerke S, Guccione JM. A Novel Method for Quantifying Smooth Regional Variations in Myocardial Contractility Within an Infarcted Human Left Ventricle Based on Delay-Enhanced Magnetic Resonance Imaging. J Biomech Eng. 2015 Aug; 137(8):081009.
  11. Jha AK, Mathur A, Svedlund FL, Ye J, Yeghiazarians Y, Healy KE. Molecular weight and concentration of heparin in hyaluronic acid-based matrices modulates growth factor retention kinetics and stem cell fate. J Control Release. 2015 Jul 10; 209:308-16.
  12. Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M, Nguyen V, Wheeler ML, Murphy MP, Sanders TA, Jeffrey SS, Yeghiazarians Y, Rinaudo PF, Costello JF, Aghi MK, Maltepe E. HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Rep. 2015 Feb 12.
  13. Jha AK, Tharp KM, Ye J, Santiago-Ortiz JL, Jackson WM, Stahl A, Schaffer DV, Yeghiazarians Y, Healy KE. Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels. Biomaterials. 2015 Apr; 47:1-12.
  14. Glenn DJ, Cardema MC, Ni W, Zhang Y, Yeghiazarians Y, Grapov D, Fiehn O, Gardner DG. Cardiac steatosis potentiates angiotensin II effects in the heart. Am J Physiol Heart Circ Physiol. 2015 Feb 15; 308(4):H339-50.
  15. Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT. Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT. IEEE Nucl Sci Symp Conf Rec (1997). 2014 Nov; 2014.
  16. Feng K, Gupta V, Terrazas E, Yeghiazarians Y, Ports T, Gregoratos G, Tavakol M, Roberts JP, Boyle A. Trans-radial versus trans-femoral access in patients with end-stage liver disease undergoing cardiac catheterization. Am J Cardiovasc Dis. 2014; 4(3):133-9.
  17. Gupta V, Feng K, Cheruvu P, Boyer N, Yeghiazarians Y, Ports TA, Zimmet J, Shunk K, Boyle AJ. High femoral artery bifurcation predicts contralateral high bifurcation: implications for complex percutaneous cardiovascular procedures requiring large caliber and/or dual access. J Invasive Cardiol. 2014 Sep; 26(9):409-12.
  18. Pandit J, Gupta V, Boyer N, Yeghiazarians Y, Ports TA, Boyle AJ. Patient and physician perspectives on outcomes weighting in revascularization. The POWR study. Int J Cardiol. 2014 Dec 15; 177(2):513-4.
  19. Boyer N, Gupta R, Schevchuck A, Hindnavis V, Maliske S, Sheldon M, Drachman D, Yeghiazarians Y. Coronary artery aneurysms in acute coronary syndrome: case series, review, and proposed management strategy. J Invasive Cardiol. 2014 Jun; 26(6):283-90.
  20. Yeghiazarians Y, Honbo N, Imhof I, Woods B, Aguilera V, Ye J, Boyle AJ, Karliner JS. IL-15: a novel prosurvival signaling pathway in cardiomyocytes. J Cardiovasc Pharmacol. 2014 May; 63(5):406-11.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.