The UCSF Asthma Clinic provides comprehensive, highly specialized care for patients with moderate to severe asthma. Our services include diagnostic testing, physiologic and allergic evaluation, optimization of medical management and education in asthma self-management.
We also have ongoing research studies to evaluate potential asthma treatments that some patients may be eligible for. Interested patients should inquire to see if they can participate.
Mechanistic Insights From Bronchoscopy Airway Samples
Specifically, gene expression will be interrogated in single cells via 10x droplet-based RNA sequencing of airway brushings obtained from bronchoscopy. The gene expression data is used to characterize individuals cells as goblet c...
The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
The primary outcome is the % change in mucus plug score from 1 week before treatment to 1 week post treatment.
Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
We will compare change in EELV during the CPET (Cardiopulmonary Exercise Test) between the obese asthma patients with MD or without MD and between the patients with severe asthma with mucus plugs or without mucus plugs.
SPIROMICS Study of Early COPD Progression (SOURCE)
Parametric Response Mapping captures the change in lung density between matched inspiratory and expiratory images thereby enabling the distinction between normal lung parenchyma (PRMNORM), emphysema (PRMEMPH), and non-emphysematou...
Tissue Immune Interaction in Nasal Polyposis
This study enrolls chronic rhinosinusitis patients with and without nasal polyps. Investigators aim to compare the percentage of ILC2 and tuft cells present in nasal tissue and secretions between those who present with nasal polyp...
Lung Function Outcomes Following Removal of Airway Mucus Plugs in Patients With Asthma (FOCUS)
We will assess change from baseline FEV1 one week after and six months after removal of mucus plugs by bronchoscopy.
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
Assessed prior to bronchodilator administration. Efficacy analyses will compare the end-of-period outcome values between test treatment and placebo.
Blood Lymphocytes in Asthmatics Treated With Therapeutic Proteins
The investigators will compare lymphocyte counts in healthy controls to asthmatics on and off therapeutic proteins.
CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment
The Effect of NAC on Lung Function and CT Mucus Score
The primary outcome is the % change in FEV1 from the start to the end of each two-week treatment period (either placebo or 20% NAC).
Awards & recognition
Among the top hospitals in the nation
No. 8 in the nation for pulmonology & lung surgery
Plan your visit
What to Bring
- Completed forms, which we will send to you before your appointment
- Insurance card
- Medications or list of medications you are taking, including dosage, method and frequency
- CD of past imaging studies, if possible