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Peyronie's Disease

Peyronie's disease is a disorder affecting about three percent of men middle-age and older. The condition is caused by the formation of dense, fibrous scar tissue, or plaque, in the penis' tunica albuginea, the sheath that surrounds the erectile tissue.

The cause of Peyronie's disease is not completely known. However, factors such as genetics and trauma to the penis, which can occur due to injury or invasive penile procedures, may contribute to the disease.

Our approach to Peyronie's disease

UCSF is a national leader in treating urological disorders, including Peyronie's disease, male sexual dysfunction, urinary incontinence, pelvic pain, urinary stone disease, male infertility and prostate disease. We offer the latest treatment techniques, and our team is committed to providing innovative, highly skilled care with compassion.

In a small percentage of cases, Peyronie's disease resolves on its own. When treatment is required, our goals are to relieve symptoms and preserve erectile function. We may use oral medications, injections or – in persistent cases – surgery.

Awards & recognition

  • usnews-neurology

    Among the top hospitals in the nation

  • usnews-urology

    Best in Northern California for urology

  • n1-2x

    in NIH funding for urology research

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.