Edward Machtinger, MD

Primary care and HIV/AIDS specialist

Dr. Edward Machtinger is a professor of medicine and director of the Women's HIV Program at UC San Francisco. Machtinger earned a medical degree at Harvard University and completed his residency in internal medicine at UCSF.

Machtinger first became interested in AIDS when he moved to New York for college in 1985 at the height of the early epidemic. He was moved by the new and historic nature of the disease, especially when a number of his friends died from AIDS. Machtinger joined Gay Men's Health Crisis, first as a "buddy" to someone dying of AIDS and later as a crisis intervention worker. On his choice of profession, Machtinger said, "AIDS, for me, became a calling and was the singular reason why I chose a career in medicine and public health."

Machtinger's passion for working with HIV-positive women began when he joined the Women's HIV Program (WHP) in 2001. He realized that the rising epidemic of HIV in women had been largely overlooked and that he could make potentially transformative contributions to both HIV-positive and at-risk HIV-negative women. He also realized that he simply loved working with women. Machtinger became director of the Women's HIV Program in 2004 and continues to support the health and well-being of his patients through clinical care at WHP.

Machtinger's primary academic interest is the relationship between HIV and violence against women. His current work is centered on developing a scalable model of trauma-informed primary care. As part of this work, he has developed interventions to help women safely and publically disclose their HIV status as a means to leave or avoid abusive partners. His recent publications include a meta-analysis describing high rates of trauma and PTSD among HIV-positive women in the United States and a study demonstrating a significant association between recent trauma and HIV antiretroviral failure. Machtinger presented his research findings at the White House to the Presidential Working Group on the Intersection of HIV/AIDS, Violence against Women and Girls, and Gender-Related Health Disparities.

Machtinger presently serves on the executive committee of the AIDS Research Institute at UCSF and on the executive committee for the oversight of congressional Ryan White funds to women and children in San Francisco; is the co-chair of the San Francisco task force on HIV-positive adolescents; and has participated in many working groups at the San Francisco Department of Public Health, developing "best practices" guidelines for the care of vulnerable populations living with HIV. Machtinger was previously the director of the Sexual Health and Empowerment Program, San Francisco's prevention-with-positives program for HIV-positive women and transgender individuals, and was co-director of the UCSF fellowship in AIDS care.

Machtinger is also a respected clinician, teacher and mentor. He was recently elected by the UCSF medical school class of 2013 to receive the UCSF School of Medicine's 2013 Osler Distinguished Teaching Award.

Machtinger's other interests include the well-being of animals and the environment as well as the relationship between human health, animal welfare and environmental stewardship.


HIV/AIDS Program
350 Parnassus Avenue, Suite 908
San Francisco, CA 94143
Phone: (415) 353-2119
Fax: (415) 353-2406

Hours: Monday to Thursday
8:30 a.m. – noon, 1 – 5 p.m.

Conditions & Treatments

Board Certification

Internal Medicine, American Board of Internal Medicine

Academic Title


More about Edward Machtinger

Additional Languages



Harvard Medical School 1996

Selected Research and Publications

  1. Hessol NA, Schwarcz SK, Hsu LC, Shumway M, Machtinger EL. Gender differences in causes of death among persons with HIV/AIDS in San Francisco, California, 1996-2013. Int J STD AIDS. 2018 Feb; 29(2):135-146.
  2. Empson S, Cuca YP, Cocohoba J, Dawson-Rose C, Davis K, Machtinger EL. Seeking Safety Group Therapy for Co-Occurring Substance Use Disorder and PTSD among Transgender Women Living with HIV: A Pilot Study. J Psychoactive Drugs. 2017 Sep-Oct; 49(4):344-351.
  3. Machtinger EL, Cuca YP, Khanna N, Rose CD, Kimberg LS. From treatment to healing: the promise of trauma-informed primary care. Womens Health Issues. 2015 May-Jun; 25(3):193-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.