Jennifer Lai, MD

Hepatologist

Dr. Jennifer C. Lai is a general and transplant hepatologist who specializes in caring for patients with chronic viral hepatitis, autoimmune disorders, and cirrhosis, particularly those awaiting liver transplantation. She is also actively engaged in patient-oriented clinical research within three major areas: integrating core principles of geriatrics (e.g., frailty, disability, palliative care, multi-morbidity) to patients with cirrhosis, investigating disparities in organ allocation and distribution as well as assessing the impact of liver donor quality on outcomes.

As the principal investigator for the NIH-funded Functional Assessment in Liver Transplantation (FrAILT) study, Lai aims to apply measures of frailty and functional status to patients with end-stage liver disease awaiting liver transplantation. Her research lays the groundwork for therapeutic interventions aimed at "pre-habilitating" patients awaiting liver transplantation to improve their outcomes and quality of life.





Lai earned her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University. She completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She is a member of the American Association for the Study of Liver Diseases, American Society of Transplantation, American Gastroenterological Association, and American College of Gastroenterology. She has been recognized as a Fellow of the American College of Physicians (FACP). Lai is board certified in Internal Medicine, Gastroenterology, and Advanced/Transplant Hepatology.

Clinics

Liver Disease and Liver Transplant
350 Parnassus Ave., Suite 300
San Francisco, CA 94143
Phone: (415) 353-2318
Fax: (415) 353-2407

Hours: Monday to Friday
8:30 a.m. – 4:30 p.m.

Liver Transplant Program
400 Parnassus Ave., Seventh Floor
San Francisco, CA 94143
Phone: (415) 353-1888
Fax: (415) 353-8917

Hours: Pre-Liver Transplant Clinic Monday, Tuesday, Wednesday 7 a.m. – 12 p.m.
Hours: Post-Liver Transplant Clinic Tuesday 8 a.m. – 12 p.m., Thursday 1-4 p.m.

Board Certification

Gastroenterology, American Board of Internal Medicine
Internal Medicine, American Board of Internal Medicine
Transplant Hepatology, American Board of Internal Medicine

Academic Title

Assistant Professor

More about Jennifer Lai

Education

Tufts University School of Medicine 2005

Residencies

New York Presbyterian Hospital 2008

Selected Research and Publications

  1. Ge J, Gilroy R, Lai JC. Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women. Hepatology. 2018 Mar 31.
  2. Puchades L, Chau S, Dodson JA, Mohamad Y, Mustain R, Lebsack A, Aguilera V, Prieto M, Lai JC. Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study. Transplantation. 2018 Mar; 102(3):e101-e107.
  3. Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS. Assessment of the Spectrum of Hepatic Encephalopathy: A Multi-Center Study. Liver Transpl. 2018 Feb 19.
  4. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Reply (to LTE HEP-17-2332). Hepatology. 2018 Jan 29.
  5. O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS. NACSELD Acute-on-Chronic Liver Failure (NACSELD-ACLF) Score Predicts 30-Day Survival in Hospitalized Patients with Cirrhosis. Hepatology. 2018 Jan 08.
  6. Bajaj JS, Rajender Reddy K, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG. Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort. Am J Gastroenterol. 2018 Apr; 113(4):556-563.
  7. Lai JC, Covinsky KE, McCulloch CE, Feng S. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis. Am J Gastroenterol. 2018 Feb; 113(2):235-242.
  8. Cullaro G, Sarkar M, Lai JC. Sex-based disparities in delisting for being "too sick" for liver transplantation. Am J Transplant. 2017 Dec 01.
  9. Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices. Clin Transplant. 2017 Dec; 31(12).
  10. Spengler EK, O'Leary JG, Te HS, Rogal S, Pillai AA, Al-Osaimi A, Desai A, Fleming JN, Ganger D, Seetharam A, Tsoulfas G, Montenovo M, Lai JC. Liver Transplantation in the Obese Cirrhotic Patient. Transplantation. 2017 10; 101(10):2288-2296.
  11. Hsu EK, Shaffer ML, Gao L, Sonnenday C, Volk ML, Bucuvalas J, Lai JC. Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List. Gastroenterology. 2017 10; 153(4):988-995.
  12. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Development of a novel frailty index to predict mortality in patients with end-stage liver disease. Hepatology. 2017 08; 66(2):564-574.
  13. Ge J, Roberts JP, Lai JC. Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States. Clin Transplant. 2017 Aug; 31(8).
  14. Wang CW, Lai JC. Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale. Clin Transplant. 2017 Jul; 31(7).
  15. Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA. A multicenter study to define sarcopenia in patients with end-stage liver disease. Liver Transpl. 2017 May; 23(5):625-633.
  16. Salazar J, Saxena V, Kahn JG, Roberts JP, Mehta N, Volk M, Lai JC. Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma. Transplantation. 2017 05; 101(5):1001-1008.
  17. Samoylova ML, Covinsky KE, Haftek M, Kuo S, Roberts JP, Lai JC. Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study. Liver Transpl. 2017 Mar; 23(3):292-298.
  18. Sinclair M, Poltavskiy E, Dodge JL, Lai JC. Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist. World J Gastroenterol. 2017 Feb 07; 23(5):899-905.
  19. Clinical Liver Disease. A framework to determine when liver transplantation is futile. 2016; 8:137-9.
  20. Pavasini R, Guralnik J, Brown JC, di Bari M, Cesari M, Landi F, Vaes B, Legrand D, Verghese J, Wang C, Stenholm S, Ferrucci L, Lai JC, Bartes AA, Espaulella J, Ferrer M, Lim JY, Ensrud KE, Cawthon P, Turusheva A, Frolova E, Rolland Y, Lauwers V, Corsonello A, Kirk GD, Ferrari R, Volpato S, Campo G. Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis. BMC Med. 2016 Dec 22; 14(1):215.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.