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John de Groot


Clinician, scientist, husband, father, swimmer and foodie

About me

Dr. John de Groot is a neuro-oncologist who specializes in diagnosing and managing the care of patients with primary brain and spine tumors (those at the site where disease began, as compared with tumors that result from the disease spreading).

De Groot has brought new therapies from the laboratory into the clinic to treat patients with brain cancer. In particular, he has contributed to the development of glioblastoma treatments. He has a special interest in using blood analyses, imaging studies and other indirect biomarkers (measurable elements that may indicate disease) to evaluate the efficacy of novel therapies. In one study, he is looking at ways to overcome physiological limitations in drug delivery to brain tumors, such as through focused ultrasound. He regularly advises and collaborates with other researchers on promising therapies under development.

De Groot earned his medical degree from the University of Texas Medical Branch at Galveston. He completed a residency in neurology at Johns Hopkins University and a fellowship in neuro-oncology at the University of Texas MD Anderson Cancer Center.

  • Education

    University of Texas Medical Branch at Galveston, MD, 1998

  • Residencies

    Johns Hopkins University, Neurology, 2002

  • Fellowships

    MD Anderson Cancer Center, Neuro-oncology, 2004

  • Academic Title


Caring for my patients reminds me of the privilege and responsibility entrusted to me.

Where I see patients (1)

    My reviews


    Overall Experience
    161 Ratings
    About our process
    Nov 10, 2023
    Dr. De Groot did a tremendous amount of background research on my medical history to help care for my present condition.
    Aug 10, 2023
    Extremely knowledgeable and provided me with information and updates. Extremely happy with Dr. De Groot.
    Jul 23, 2023
    Ovee well rounded discussion covering all topics
    May 11, 2023
    Thank you for clear answers
    Apr 14, 2023
    Dr. DeGroot was very kind personable and reassuring. His knowledge of the situation and treatment process is a great benefit to the patient.
    Apr 12, 2023
    Excellent doctor
    Apr 08, 2023
    Dr. De Groot is one of the best Doctors I've never had! I'm blessed to have had him help me
    Mar 03, 2023
    It was a good experience.
    Feb 22, 2023
    Dr. De Groot was wonderful. Knowledgeable pleasant explained things clearly.
    Feb 12, 2023
    Would have like to understand clearly what the purpose of the appointment was. I felt I didn't get much from the meeting.
    Feb 02, 2023
    It was hard to tell because pathology wasn't back yet.
    Dec 01, 2022
    The team is a breath of fresh medical air!
    Nov 10, 2022
    He answered our questions well and met our expectations for a second opinion at a research institution.
    Oct 28, 2022
    I was unaware of an increase in the chemo dosage from 250 mg to 360 mg per day. No mention was made of that possibility at our appointment even though I confirmed the dosage of 240 mg specifically. I found out of the increase when I called the UCSF pharmacy to check on the prescription. The pharmacist confirmed the increase with the oncology team fir me and made sure a note was sent to the external pharmacy handling the medication dispense just to make sure there weren't back and forth delays caused by the increase.
    Oct 27, 2022
    Excellent doctor
    Sep 02, 2022
    Absoluutely would recommend
    Aug 13, 2022
    I had a problem getting a prescription I needed which was the reason for my visit. I would have been better off going to outside urgent care.
    Jul 29, 2022
    We were profoundly moved by the degree of heartfelt listening and compassion rendered by Dr. DeGroot. I have never experienced this degree of compassion from a medical person. We hope this message gets to him.
    Jul 14, 2022
    I needed more information about timing of aspects for my treatment plan.
    Jun 09, 2022
    I feel I'm in the best place I could be. Grateful for having Groot as my dr. And all the other workers there
    May 07, 2022
    Dr. De Groot is amazing!
    Apr 07, 2022
    I'm very glad Dr de Groot is my neuro-oncologist.
    Mar 13, 2022
    Dr. De Groot is amazing
    Decorative Caduceus

    Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tum...

    All adverse events and/or Serious Adverse Events will be documented and reported according to CTCAE