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Dr. Liviu Klein, a cardiologist at the UCSF Heart & Vascular Center, is director of Advanced Heart Failure Comprehensive Care Center and director of the Mechanical Circulatory Support Program. He specializes in caring for patients with heart failure and arrhythmias, including care before and after surgery for those receiving heart transplants. He also has expertise in cardiac resynchronization and mechanical therapies, such as ventricular assist devices for heart failure.

In his research, Klein studies the epidemiology of heart failure in women, including those at risk for sudden cardiac death. Together with colleagues in the Department of Bioengineering and Therapeutic Sciences, he is developing new technologies for monitoring and treating patients with heart failure and other kinds of cardiovascular disease, including those who use ventricular assist devices.

Klein earned a medical degree at the Carol Davila University of Medicine in Bucharest, Romania. He earned a master's of science degree in clinical investigation at Northwestern University. He completed a residency in internal medicine at the Advocate Illinois Masonic Medical Center in Chicago and a fellowship in cardiovascular epidemiology at Northwestern University's Feinberg School of Medicine. At Northwestern's McGaw Medical Center, he completed fellowships in cardiovascular disease, advanced heart failure and heart transplantation, and in clinical cardiac electrophysiology.

Klein is a member of the American Heart Association, Heart Failure Society of America and International Society for Lung and Heart Transplantation. He has published more than 100 peer-reviewed articles and books.

  • Board Certifications

    American Board of Internal Medicine, Advanced Heart Failure & Trans

    American Board of Internal Med/Cardiovascular Dis, Cardiovascular Disease

  • Fellowships

    McGaw Medical Center of Northwestern University, Cardiac Electrophysiology

    McGaw Medical Center of Northwestern University, Cardiovascular Disease

    McGaw Medical Center of Northwestern University, Advanced Heart Failure and Transplant Cardiology

    Northwestern University Medical School, Cardiovascular Epidemiologist

  • Residencies

    Illinois Masonic Medical Center-GME, Internal Medicine

  • Internship

    Illinois Masonic Medical Center-GME, Internal Medicine

  • Degree

    MD, Universitatea De Medicina Si Farmacie

  • Languages

    Romanian

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"You have to be like a detective and figure out which condition led to heart failure."

The future of cardiac care relies on ongoing connectivity with patients to delay disease progression and improve quality of life.

Where I see patients (5)

    My reviews

    4.9

    Overall Experience
    87 Ratings
    About our process
    Aug 25, 2025
    They show their concern if any and always explain things to the fullest
    Jul 23, 2025
    Q&A session between client and provider concluded further clear instructions
    May 16, 2025
    Excellent my experience was very good to hear the results of my treatment.
    May 09, 2025
    Yes, I recommend them
    Apr 12, 2025
    Dr. Klein is wonderful! Brilliant and compassionate.
    Apr 05, 2025
    Awesome people...
    Nov 08, 2024
    Dr Klein is definitely and easily one of Dr's I have dealt with in my 55 years on Earth
    Sep 28, 2024
    Dr Klein was very kind and considerate. He showed care and concern. If I could I would give him a 5+ rating
    Aug 17, 2024
    Has an incredible way of easing your anxiety and fears by discussing a care plan that includes immediate treatment and if that doesn't work, then we can do this, including follow up appts & calls.
    Jun 14, 2024
    Excellent experience
    May 19, 2024
    Dr. Klein is amazing.
    May 03, 2024
    Above expectations
    Mar 29, 2024
    Dr. Klein is an amazing physician. Both brilliant and compassionate. He was also my late husband's Cardiologist.
    Decorative Caduceus

    US National OCS Heart Perfusion (OHP) Registry

    Recipients' patient and graft survival rates will be the primary clinical outcomes measures for all OCS Heart transplanted recipients compared to recipients receiving heart transplants using non-OCS preservation methods (cold stat...

    Recruiting

    Decorative Caduceus

    Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present Wi...

    MAE defined as: 1. All-cause death, 2. Myocardial infarction, 3. Stroke, 4. Need for non-elective cardiovascular surgery, 5. Worsening of heart-failure requiring mechanical circulatory support for more than 24 ...

    Recruiting

    Decorative Caduceus

    Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

    Exercise pulmonary capillary wedge pressure (PCWP) will be measured at peak exercise at approximately six months post-Barostim titration and compared with peak exercise PCWP measured during the pre-implantation phase. Change from ...

    Recruiting

    Decorative Caduceus

    Enhancing Heart Allograft Function With the OCS Heart System Trial

    The primary endpoint is 30-day patient and graft survival with freedom from moderate or severe LV or RV primary graft dysfunction (PGD) in the first 24 hours post-transplant.

    Recruiting

    Decorative Caduceus

    Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

    Incidence of Major Adverse Events

    Recruiting

    Decorative Caduceus

    DORAYA-HF Early Feasibility Study

    Device or procedure related SAEs rate (including MACE) based on CEC adjudication.

    Recruiting

    Decorative Caduceus

    AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SY...

    Until the end of the study, each participant will be assigned to one of the following event outcomes: 1. Having at least one protocol-defined Heart Failure Event (HFE) in the CORE period 2. Having no Heart Failure Event (HFE...

    Recruiting

    My work

    Coordinated care saves patient after heart attack

    After John's heart stopped, Dr. Klein and a team of cardiac specialists at UCSF helped the former police officer make a full recovery. "I'm very grateful."

    UCSF's 35 years of heart transplant experience

    A leader in treating advanced heart failure, UCSF performed nearly 80 heart transplants in 2023. Dr. Klein shares his perspective on our commitment to cutting-edge care.

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