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Dr. Paul J. Sampognaro is a neurologist who specializes in caring for patients with neuromuscular disorders, including myasthenia gravis, peripheral neuropathy, myopathy and amyotrophic lateral sclerosis (also called ALS or Lou Gehrig's disease).

In his research, Sampognaro investigates how ALS develops at the molecular level.

Sampognaro earned his medical degree from the Johns Hopkins School of Medicine. At UCSF, he completed a residency in neurology and a fellowship in neuromuscular medicine.

  • Board Certifications

    American Board of Psychiatry and Neurology, Neuromuscular Medicine, 2020

    American Board of Psychiatry and Neurology, Neurology, 2018

  • Fellowships

    UCSF, Neuromuscular Medicine, 2019

  • Residencies

    UCSF, Neurology, 2018

  • Internship

    UCSF, Neurology, 2015

  • Education

    Johns Hopkins University School of Medicine, 2014

  • Languages

    English

Where I see patients (2)

    My reviews

    5.0

    Overall Experience
    200 Ratings
    About our process
    Mar 29, 2025
    I couldn't ask for a better provider to help me deal with this ailment
    Mar 22, 2025
    Dr. S has a very relaxed manner. Easy to talk to. Talks to you, not down to you. Great bedside manner. Asks great questions - and then (really) listens to your answers.
    Mar 15, 2025
    Dr Sampognaro is one of the best physician I ever experienced. He is very patient and care
    Mar 11, 2025
    Dr Paul S is the best
    Mar 01, 2025
    Dr. Sampognaro is the best doctor that I've ever dealt with he listens to all of my concerns and gives me all the feedback is professionalism is outstanding. Your facility could not ask for a better person. I would truly recommend the doctor to any family members friends, etc.
    Mar 01, 2025
    Dr Sampognaro was extremely patient and went over all of my concerns and questions. Even though I was upset by the information he continued to show compassion and explain until I understood. He is AMAZING!!
    Feb 09, 2025
    Dr. Paul is outstanding! I have been to multiple Neurologists since my health care issues. He's wonderful!
    Feb 04, 2025
    Dr. Sampognaro gave me his full attention when we went into his office. He looked directly at me when we were talking, and took his time to listen to my needs and concerns. He asked meaningful questions to clarify and offered helpful suggestions. He also explained things very clearly and thoroughly, so that I was able to understand exactly what was going on better than anyone I've seen to date. His examination was very thorough, leaving no stone unturned. I felt very lucky that I had such a professional, helpful, caring doctor for this appointment. I left feeling more hopeful than I've felt for some time about my condition and the future. I would highly recommend him to my friends.
    Feb 02, 2025
    Dr. Sampognaro is the most caring Doctor I have! He is so sincere and extremely caring.
    Feb 01, 2025
    Couldn't have been better!
    Jan 26, 2025
    Dr. Sampagnaro is an excellent, compassionate Neurologist. I am blessed and grateful for his help in guiding me through the process of my diagnosis and treatment. I would highly recommend Dr. Sampagnaro.
    Jan 25, 2025
    That's why I call him the good Doctor Paul!
    Jan 21, 2025
    Dr. S handles himself very well. He is professional and cares. He listens to you. If he doesn't know something, he says so. He is honest.
    Jan 18, 2025
    Dr. Sampagnaro is best in class
    Jan 11, 2025
    I would rate Dr. Paul S. Above "excellent" in response to all questions. Great visit.
    Dec 28, 2024
    Each team member gave me good advice and supported my concerns.
    Dec 09, 2024
    The Dr. Sanpognaro was amazing! He is my 4th Neurologist and the 1st to actually want to find the root cause of my issues. 10/10 recommend him!
    Nov 17, 2024
    Everyone involved had been great
    Oct 26, 2024
    Doctor was amazing. Listen to my problems and suggested medications that may help. Was prescribed and able to pick up later that evening. Gave me clear info and suggestions for the future. Very happy with the appointment.
    Oct 26, 2024
    I have never received better care than I have received from Dr. Sampognaro! He is the best!!!!
    Oct 19, 2024
    The doctor was very personable and knowledgeable. He explained everything clearly and when I didn't understand found ways to explain until I did. I feel completely confident in him and am so happy that I found him and UCSF.
    Sep 28, 2024
    I am exceptionally grateful and appreciate how completely Dr. P. Sampognaro explains the topic and answers my questions. I am very happy to be in his and his teams care. Thank you!
    Sep 28, 2024
    Dr. Paul explained clearly to me how he is going to address my treatment, and the steps and tests he Is taking to determine my condition.
    Sep 23, 2024
    Dr. Sampognaro is simply great!
    Sep 21, 2024
    Dr. Sampognaro has given me excellent treatment!
    Sep 21, 2024
    He is the best Doctor ever!
    Sep 14, 2024
    He was superb. The best in all categories!!
    Sep 08, 2024
    Dr Sampognaro is an excellent doctor every way
    Aug 31, 2024
    He was gentle and explained everything from start to finish. We also had a beautiful conversation
    Aug 24, 2024
    Dr. Paul instilled confidence in me that we are on this journey together with an experienced and dedicated team.
    Aug 17, 2024
    Very good doctor
    Aug 17, 2024
    Dr. Sampognaro is always so kind, listens well and left me with a clear plan to follow up.
    Aug 17, 2024
    Excellent Doctor. He is caring and very wise and knowledgeable.
    Aug 10, 2024
    Dr. Sampagnaro is an excellent doctor and I appreciate his care.
    Aug 10, 2024
    Extremely kind, informative and inclusive provider
    Jul 27, 2024
    Dry. Sampanaro is outstanding!!!!
    Jul 27, 2024
    My problems are just outside his area of expertise but he was able to understand and guide and add to my understanding and refer me to the right expertise and offered to help with follow up since my problems are unusual. This is rare.
    Jul 20, 2024
    It was well worth the time this is my go to guy for any on going issues, thank you Doctor
    Jul 15, 2024
    Dr. Sampognaro Is an excellent doctor he listens to any concerns I may have and answers any questions to the fullest extent. He makes sure that Iis an excellent doctor he listens to any concerns I may have and answers any questions to the fullest extent. He makes sure that I totally understand any changes or follow ups Are totally understandable
    Jul 13, 2024
    Exceptionally good doctor/carejust the best
    Jul 06, 2024
    Kind, compassionate, knowledgeable..the best
    Jun 29, 2024
    Dr. S is very easy to work with. He listens. He explains. Makes complex topics easy to understand.
    Jun 24, 2024
    Dr Sampognaro is one of the best health care provider I have had in my lifetime.He always takes time to listen to my concerns and answers my questions without rushing me.
    Jun 23, 2024
    My provider was attentive, listened patiently to my issue. He didn't make me feel uncomfortable when I was speaking. I walked out of their feeling that I was going to actually get results with the treatment we decided together. He gave me options, explained in detail what they were and the outcome of each, then we both came to an agreement on which one would be best. I am ever so thankful that I may get better in the near future. Thank you so much, UCSF for being there.
    Jun 22, 2024
    Dr Sampogaro is very thorough understanding and the best
    Jun 03, 2024
    The best!
    May 27, 2024
    They were the best
    May 27, 2024
    He was excellent
    May 25, 2024
    Dr was very kind, caring and helpful!
    May 25, 2024
    One of the most satisfying experience with a Doctor that I have had.
    May 13, 2024
    Dr. Sampagnaro is in a special class of doctors. He is one of very few that have not written me off due to my age, but instead is active in listening to my life goals and providing the best feed back and support he can. It's truly remarkable when you experience such world class service. I could not be more grateful to have Dr.Sampagnaro on my team of caregiver.
    May 13, 2024
    Easy back & forth with Paul. He was friendly, prepared and professional. He discussed his involvement as "another set of eyes" on my case - working closely and in concert with Dr. Tugizova.
    May 05, 2024
    Excellent
    May 05, 2024
    Exemplary, we love Dr. Paul S.
    May 04, 2024
    Dr Sampognaro is fantastic
    Apr 22, 2024
    My care provider is so knowledgeable and takes all questions seriously. He answers my questions with pride and respect Dr Paul Sampognaro is the best Dr I have seen
    Apr 21, 2024
    Exceptional in every way.
    Apr 16, 2024
    Explained the procedure and what the findings might be. Good sense of humor. Made me feel comfortable with the procedure.
    Apr 15, 2024
    I would rate Dr. Sampognaro a 10 if I could..He is patient, generous with sharing information, compassionate, and has high expertise. This neurological field is highly demanding and exhausting for anyone who cares for patients. I am forever grateful to Dr. S.
    Mar 25, 2024
    Dr Sampognaro, very reassuring and thorough
    Mar 23, 2024
    Could not have asked for a better session. Dr Sampagnaro was attentive, empathetic and fully engaged. Left the session very confident that even if my symptoms don't improve, UCSF is doing everything to address them
    Mar 23, 2024
    Doctor was great. I call him the good doctor Paul!
    Mar 16, 2024
    Dr Paul is excellent. He explains things very well and listens and explain our questions
    Mar 10, 2024
    Dr. Sampagnaro is an excellent doctor
    Mar 09, 2024
    Dr.Sampagnaro is the epitome of an exceptional doctor. His engagement, empathy, brilliance, and outstanding bedside manner makes him a standout healthcare provider. I highly recommend Dr. For his unparalleled care and genuine dedication to patients.
    Mar 06, 2024
    My provider, very thorough. He communicates very well listens to any questions that I may have or concerns. His follow up is excellent. I can ask for a better doctor.
    Oct 30, 2023
    A truly compassionate physician.
    Oct 21, 2023
    Dr. S is The best..demonstrates care, concern, empathy, shares information, answers all questions, highly knowledgeable.
    Oct 09, 2023
    Doctor Paul is a great doctor. He really cares for his patients.
    Oct 08, 2023
    Dr. Sampognaro is Excellent. He listens. Pays attention, helps me reasoning different alternatives/scenarios, explains and demonstrates interest in my case. Excellent physician and superb human being.
    Oct 07, 2023
    Very friendly and will explain everything clearly
    Sep 25, 2023
    Excellent rapport
    Sep 16, 2023
    The Dr and his team were exceptional. Very empathetic very compassionate and very experienced.The best Dr patient experience I have had.
    Sep 05, 2023
    Thank you! Love you! Excellent!!
    Sep 02, 2023
    Dr Paul Sampognaro is so caring and considerate and knowledgeable
    Sep 01, 2023
    Dr. Sampognaro and his team are outstanding! Dr. Sampognaro and his team take time to listen , discuss , offer recommendations to manage my case . Thank you - a stellar team .
    Aug 19, 2023
    I wanted to take a moment to share my heartfelt recommendation for Dr. Sampognaro, who has been an incredible neurologist in managing my Myasthenia Gravis. His brilliance and dedication have not only helped me retain my independence but have also given me hope for a brighter future.Under Dr. Sampognaro's care, I have experienced significant improvements in my health and overall well-being. His deep understanding of Myasthenia Gravis and his commitment to staying up-to-date with the latest advancements in neurology have made a real difference in my treatment.Dr. Sampognaro goes above and beyond for his patients. He takes the time to listen to my concerns, answer my questions, and develops personalized treatment plans that are tailored to my specific needs. His attention to detail and comprehensive approach have been instrumental in managing my condition.What sets Dr. Sampognaro apart is not only his medical expertise but also his compassion and empathy. He understand the emotional toll of living with a chronic illness and provide not only medical care but also invaluable emotional support. His unwavering dedication to my well-being has been a source of comfort and encouragement.
    Aug 05, 2023
    Dr Paul Sampognaro is a great Dr. All my visits have been such a great experience
    Jul 31, 2023
    Excellent experience. I felt heard, understood and cared for. Many topics of concern were covered thoroughly and all my questions and concerns were addressed. Most importantly, I was treated with dignity, respect and compassion.
    Jul 23, 2023
    Dr. Sampognaro is excellent. He is vero knowledgeable, caring, listens, discusses alternatives, engages the patients to speak up and look for the best alternatives/solutions/treatments. I always come out very hopeful and assured am in good hands after visiting Dr. Sampognaro. I appreciate very much his services.
    Jul 10, 2023
    Doctor Paul S. Been very thorough in physical examination, reviewing medical records and explaining his treatment plan
    Jul 08, 2023
    Dr. Paul S was very friendly and checked me thouroly He will run another test to determine my condition
    Jul 01, 2023
    Wonderful experience!1
    Jul 01, 2023
    Dr Sampognaro is fantastic. He possesses a combination rare in a doctor- expertise, knowledge, humility, humor, patience, empathy, open mindedness, not rushed, listens and responds to all concerns, insightful, goes above and beyond in keeping track of patients - late into the night if needed. I cannot say enough positives about him.
    Jun 17, 2023
    Dr Sampognaro is outstanding in the care he provides
    Jun 07, 2023
    Dr Sampagnaro is the most sensitive, caring, knowledgeable doctor I have ever worked with
    Jun 03, 2023
    Dr. Sampagnaro is extremely caring, compassionate and knowledgeable. I feel so fortunate and grateful to be in his care!

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