Tippi C. Mackenzie


Fetal and pediatric surgeon

Dr. Tippi MacKenzie, a pediatric surgeon at UCSF Benioff Children's Hospital and its Fetal Treatment Center, has special interests in fetal surgery, advanced laparoscopy, and endocrine and biliary surgery. She is a member of the Biomedical Sciences Program and Institute for Regeneration Medicine, with a research focus on stem cell transplantation in utero to treat genetic disease.

MacKenzie earned a medical degree at Stanford University and completed a general surgery residency at Brigham and Women's Hospital in Boston. She completed a pediatric surgery fellowship at the Children's Hospital of Philadelphia, where she held a clinical appointment in general, thoracic and fetal surgery.

  • Education

    Stanford School of Medicine, 1997

  • Residencies

    Brigham and Women's Hospital, Surgery, 1999

    Children's Hospital of Philadelphia, Pediatric Surgery, 2002

  • Fellowships

    Children's Hospital of Philadelphia, Pediatric Surgery, 2007

  • Board Certifications

    Surgery, American Board of Surgery

    Pediatric Surgery, American Board of Surgery

  • Academic Title


Clinics I work with

Fetal Treatment Center

Betty Irene Moore Women's Hospital

1855 Fourth St., Second Floor, Room A-2432
San Francisco, CA 94158


"A lot of mothers will undergo any procedure to save the life of their child. It's up to us to make sure what we're offering them has the potential for true benefit and a minimal risk of harm."

Decorative Caduceus

International Registry of Patients With Alpha Thalassemia

Number of fetuses diagnosed with alpha thalassemia who survive to birth, compared to number of fetuses diagnosed with alpha thalassemia who have fetal demise or are terminated in utero. This is measured in number of fetuses alive ...


Decorative Caduceus

In Utero Enzyme Replacement Therapy for Lysosomal Storage Diseases

Adverse and serious adverse events including, but not limited to, death within 24 hours after the procedure, stillbirth, death prior to initial hospital discharge,increased response with antibody development above that expected wi...


Decorative Caduceus

In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)

Maternal participant tolerance of bone marrow harvest defined as not requiring interventions for preterm labor, bleeding, infection or prolonged hospitalization.


My work

Our programs: UCSF Center for Maternal-Fetal Precision Medicine
Read on Statnews

Can gene therapy halt diseases in babies before they’re even born?

Read on Statnews