Tammy T. Chang, PhD, MD

Gastrointestinal surgeon

Dr. Tammy T. Chang is a gastrointestinal and acute care surgeon. Chang also runs a research laboratory that focuses on liver tissue engineering and regenerative surgical therapies.

Chang earned her combined medical and doctoral degrees at Harvard Medical School. She then completed her general surgery residency training and fellowship in advanced gastrointestinal minimally invasive surgery at UCSF.

Chang is an assistant professor of surgery at UCSF.

Clinics

Gastrointestinal Surgery at Parnassus
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143-0388
Phone: (415) 353-2161
Fax: (415) 353-2505

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Board Certification

Surgery, American Board of Surgery

Academic Title

Assistant Professor

More about Tammy T. Chang

Education

Harvard School of Medicine 2003
Harvard Graduate School of Arts and Sciences , Ph.D., Immunology 2003

Residencies

UCSF , General Surgery 2010

Fellowships

UCSF , Advanced GI Minimally Invasive/Bariatric Surgery Fellowship 2011

Selected Research and Publications

  1. Chang TT, Zhou VX, Rubinsky B. Using non-thermal irreversible electroporation to create an in vivo niche for exogenous cell engraftment. BioTechniques. 2017; 62:229-231.
  2. Chang TT, Zhou VX, Rubinsky B. Using non-thermal irreversible electroporation to create an in vivo niche for exogenous cell engraftment. Biotechniques. 2017 05 01; 62(5):229-231.
  3. Chang TT. Reply. Hepatology. 2017 05; 65(5):1781-1782.
  4. Zhou VX, Lolas M, Chang TT. Direct orthotopic implantation of hepatic organoids. J Surg Res. 2017 May 01; 211:251-260.
  5. Chang TT, Thakar D, Weaver VM. Force-dependent breaching of the basement membrane. Matrix Biol. 2017 01; 57-58:178-189.
  6. Choi WT, Chang TT, Gill RM. Gastrointestinal Zygomycosis Masquerading as Acute Appendicitis. Case Rep Gastroenterol. 2016 Jan-Apr; 10(1):81-7.
  7. Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Espaņol-Suņer R, Willenbring H, Weaver VM, Chang TT. Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha. Hepatology. 2016 07; 64(1):261-75.
  8. Hughes-Fulford M, Chang TT, Martinez EM, Li CF. Spaceflight alters expression of microRNA during T-cell activation. FASEB J. 2015 Dec; 29(12):4893-900.
  9. Chang TT, Spurlock SM, Candelario TL, Grenon SM, Hughes-Fulford M. Spaceflight impairs antigen-specific tolerance induction in vivo and increases inflammatory cytokines. FASEB J. 2015 Oct; 29(10):4122-32.
  10. Chang TT, Hughes-Fulford M. Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregates. Biomaterials. 2014 Feb; 35(7):2162-71.
  11. Chang TT, Walther I, Li CF, Boonyaratanakornkit J, Galleri G, Meloni MA, Pippia P, Cogoli A, Hughes-Fulford M. The Rel/NF-?B pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity. J Leukoc Biol. 2012 Dec; 92(6):1133-45.
  12. Chang TT, Hughes-Fulford M. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes. Tissue Eng Part A. 2009 Mar; 15(3):559-67.
  13. Chang TT, Corvera CU. Caudate split for open and laparoscopic liver resections. J Am Coll Surg. 2008 Dec; 207(6):e7-9.
  14. Chang TT, Sawhney R, Monto A, Davoren JB, Kirkland JG, Stewart L, Corvera CU. Implementation of a multidisciplinary treatment team for hepatocellular cancer at a Veterans Affairs Medical Center improves survival. HPB (Oxford). 2008; 10(6):405-11.
  15. Chang TT, Schecter WP. Injury in the elderly and end-of-life decisions. Surg Clin North Am. 2007 Feb; 87(1):229-45, viii.
  16. Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. Eur J Immunol. 2003 Jul; 33(7):2022-2032.
  17. Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. Eur J Immunol. 2002 Sep; 32(9):2687-97.
  18. Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, Berry G, DeKruyff RH, Umetsu DT. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med. 2002 Sep; 8(9):1024-32.
  19. Chang TT, Kuchroo VK, Sharpe AH. Role of the B7-CD28/CTLA-4 pathway in autoimmune disease. Curr Dir Autoimmun. 2002; 5:113-30.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.