Anal Neoplasia Clinic, Research and Education (ANCRE) Center

The Anal Neoplasia Clinic, Research and Education (ANCRE) Center, part of the UCSF Helen Diller Family Comprehensive Cancer Center, is the world's first clinic devoted to anal cancer prevention. Having been the first to identify the link between neoplasias (precancerous lesions) and anal cancer, UCSF experts remain global leaders in the field.

Anal cancer is on the rise in the U.S., and the vast majority of cases are caused by human papillomavirus (HPV). This virus is extremely common among sexually active people and can lead to precancerous changes in the anal tissue, which may progress to anal cancer. Most of the time, a healthy immune system can clear the virus, but particularly in immunocompromised people, certain strains of the virus can persist, increasing cancer risk. That’s why our goal at the ANCRE Center is to provide the close monitoring and therapies that can reduce that risk.

Our center offers a wide range of screening, diagnostic and treatment options, including anal cytology, high-resolution anoscopy, anal biopsy, infrared coagulation therapy and electrocautery therapy. ANCRE’s doctors not only provide top-tier care, they conduct research on anal neoplasia, giving our patients access to the latest and best techniques and therapies.

Our locations

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    Decorative Caduceus

    Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grad...

    The log-rank test will be used to compare the treatment and control arms with respect to time to detection of anal cancer. For each arm, the hazard rate and its 95% confidence interval will be estimated. The proportional hazards m...

    Recruiting

    Decorative Caduceus

    Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classi...

    Will be defined as the starting dose level at which 1/6 subjects experience dose limiting toxicity (DLT) with the next higher dose having at least >= 2 participants encountering DLT. Toxicity data will be presented by type and sev...

    Recruiting

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    Related clinics

    Center for Colorectal Surgery

    Bakar Precision Cancer Medicine Building

    1825 Fourth St., Fourth Floor
    San Francisco, CA 94158

    Our research initiatives

    • UCSF Anal Cancer Research

      The UCSF Anal Neoplasia Clinic, Research and Education Center participates in research aimed at improving the understanding and treatment of anal neoplasia and cancer.

    • UCSF-Helen-Diller-Family-Comprehensive-Cancer-Center-Research-2x

      UCSF Helen Diller Family Comprehensive Cancer Center Research

      UCSF is home to a range of research initiatives aimed at improving outcomes for cancer patients everywhere. This includes research on topics such as immunotherapy, BRCA mutations and molecular diagnostic testing.

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