Have you and your family had your flu shot? It's more important than ever this year! Schedule via MyChart or call for an appointment in SF, the East Bay or San Mateo.
Overview

Hepatic Porphyria

Porphyrins are pigments made by the liver and other tissues. They are involved in the formation of many important substances in the body, such as hemoglobin, which carries oxygen in the blood.

Many genes are involved in the production of porphyrins. If one of these genes is mutated, hepatic porphyria may occur, resulting in an abnormal increase of pigments in the body. There are two types of porphyria: cutaneous and acute.

Genetic porphyria often is "silent," meaning that the genetic change causes symptoms only in the presence of certain environmental triggers, such as alcohol consumption, inadequate diet and certain medications — especially sedatives related to barbiturates, anti-seizure drugs and oral contraceptives. Excess iron and estrogen play a role in some patients, and there also is a frequent association with hepatitis C liver disease.

Our Approach to Hepatic Porphyria

UCSF's dedicated team of hepatologists delivers cutting-edge, compassionate care for all kinds of liver disorders, including hepatic porphyria. Treatment for hepatic porphyria focuses on avoiding triggers – such as alcohol consumption or too much iron in the body – that lead to symptoms.

Patients with excess iron may need to have set amounts of blood withdrawn at regular intervals. Over time, this lowers iron to normal levels and decreases symptoms such as sun sensitivity.

Awards & recognition

  • usnews-neurology

    Best hospital in Northern California

  • Best in Northern California in gastroenterology & GI surgery

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

Share