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Dr. Umesh Masharani is an endocrinologist who cares for patients with diabetes and thyroid disorders. He also has an endocrine faculty practice.

Masharani's research focuses mainly on diabetes, with a particular interest in insulin resistance. He collaborates with colleagues in the family medicine departments to examine the relationships among glucose control, depression and psychosocial stress in people with diabetes. He is part of the islet auto-transplantation group, which has an active program managing patients who require surgical removal of the pancreas for chronic pancreatitis and are candidates for islet auto-transplant, a procedure that allows the patient's body to continue producing insulin. The islet transplant group is also studying donor islet transplants as a treatment for type 1 diabetes.

In addition, Masharani is collaborating with Dr. George Brooks, a professor of integrative biology at the University of California, Berkeley, to examine the impact of exercise and aging on mitochondrial function.

Masharani earned his bachelor's degree in physiological sciences at the University of Oxford. He earned his medical degree at Middlesex Health in London. He completed his residency in internal medicine at University Hospitals Birmingham NHS Foundation Trust in Birmingham, England. He completed a fellowship in endocrinology at UCSF.

  • Education

    University of Oxford, BA, Physiological Sciences, 1979

    Middlesex Health, MBBS, 1982

  • Residencies

    University Hospitals Birmingham, Internal Medicine, 1985

  • Fellowships

    UCSF, Endocrinology, 1993

  • Board Certifications

    Endocrinology Diabetes and Metabolism, American Board of Internal Medicine

  • Academic Title


  • Languages


Where I see patients (7)

    My reviews


    Overall Experience
    306 Ratings
    About our process
    Dec 01, 2023
    He's fair & good doctor
    Nov 22, 2023
    I have referred others to him because he's friendly concern about my treatment & appointments & my well-being.
    Nov 18, 2023
    Nov 17, 2023
    Dr. Masharani is the best!
    Nov 12, 2023
    Oct 30, 2023
    Dr. Masharani is fantastic. I feel blessed to be his patient.
    Oct 17, 2023
    Dr Masharani is an excellent practitioner. I trust him with my health care decisions.
    Oct 14, 2023
    Dr. Masharani is the best. He is informed up to date and such a kind and caring doctor. My favorite!
    Sep 26, 2023
    Dr. Masharani is absolutely the best physician I have ever worked with. He is professional caring and has the best bedside manner.
    Sep 20, 2023
    I can't say enough positive things about Dr. M. He's extremely knowledgeable about the state of the art in diabetes care very compassionate and an excellent communicator. I have had diabetes for 46 years and yet I am STILL able to learn from him!
    Sep 08, 2023
    Care provider is excellent in all aspects of health care delivery.
    Aug 27, 2023
    Dr. Masharani is an old school master clinician whose bedside demeanor clinical expertise knowledge ability to explain the condition in simple terms and overall care and compassion are outstanding and unparalleled. His medical art and care are a rare find in modern medicine and he is a true gem who I hope is highly valued at UCSF. He and doctors like him are what make UCSF great.
    Aug 23, 2023
    This is about the doctor not the assistany
    Aug 23, 2023
    Exceptional physician who didn't jump to a quick fix but truly listened to my concerns. Would highly recommend
    Aug 23, 2023
    Good customer service
    Jul 07, 2023
    Dr Masharani is the best!!
    Jun 25, 2023
    I have good providers.
    Jun 05, 2023
    Dr.Masharani one of the greatest doctors I have ever met.
    Jun 04, 2023
    Dr. Masharani is one of my favorite doctors of all time. Competent compassionate attentive. His great sense of humor is the cherry on top. He's the best!
    Jun 02, 2023
    The reception nursing and Dr. M are the best!!!
    May 06, 2023
    I love my Dr at UCSF he is kind & smart and I trust his decision making
    May 05, 2023
    I am very fortunate to be under the care of Dr Masharani.
    Apr 25, 2023
    Dr Masharani is very knowledgeable. I trust him with my endocrine care plus what is safe to keep my transplanted kidney. He is also tough but sympathetic to my disease
    Apr 20, 2023
    Very attentive and concerned
    Apr 08, 2023
    I feel so fortunate to have this team looking after my care. I do not have enough positive words to fully capture my appreciation for this visit.
    Apr 07, 2023
    Fantastic doctor who cares and THINKS! Love that. He is researching and gathering information about possible new drug and issues related with anti-rejection drugs.
    Apr 04, 2023
    Another excellent visit with a fantastic provider.
    Mar 28, 2023
    Dr. Masharani has excellent bedside manner and an excellent clinician.
    Mar 25, 2023
    Mar 18, 2023
    It is very important I know I can trust my health providers. UCSF has proved over and over that almost everybody from the Valet service to Surgeons appear to care. And I have recommended your Health care service.
    Mar 15, 2023
    I really appreciate Dr. Masharani's speediness in responding to questions and concerns.
    Mar 12, 2023
    Dr. Masharani is a very kind thoughtful and listens to my concerns/issues. He's always well versed in the latest treatment options.
    Jan 28, 2023
    It was a relief to be speaking with providers who are familiar with my condition and had seen other patients with the same challenges
    Jan 16, 2023
    Umesh Masharani is one of the most pleasant and delightful physicians I've EVER encountered. Professionals all listening so professional and complete. Really makes you feel at home and confident that he is putting the entire person (me) and my health at his focus to provide the best care possible. Truely one of the best physicians I've ever worked with our met. I'm lucky to have him as a provider. I feel I'm getting the best endo care I could get anywhere.
    Jan 16, 2023
    Excellent physician. More inclined to look at statistics than the individual patient.
    Jan 08, 2023
    I have been with Dr. Masharani since 2009. I feel so fortunate to have him as my health advocate!
    Dec 16, 2022
    Dr. Masharani is a great doctor. He listened carefully to my needs and addressed them completely and efficiently. He also reviewed my recent records beforehand and knew exactly what my current condition was.
    Dec 15, 2022
    Understands my difficult medical situation.
    Dec 14, 2022
    I felt like my concerns and symptoms were dismissed. He seems satisfied with my quality of life when I am not and sees no role for himself in helping me. He refused to follow up on my concerns.
    Dec 08, 2022
    Dr Masharani is truly empathetic! He cares!
    Nov 25, 2022
    I really like him he is one of the best doctors I've ever had.
    Nov 15, 2022
    Made me very comfortable during the visit.was a very informative visit.
    Oct 29, 2022
    Dr M is very forward thinking. Unfortunately I am aging. Dr M orders tests to anticipate any problems I might encounter. When testing results indicate a potential problem Dr M recommends strategies before the problem becomes more advanced. Isn't that great? Previous physicians have not been so keen in this area.
    Oct 14, 2022
    Dr Masharani is an excellent caring physician.
    Oct 07, 2022
    Dr. Masharani is top notch. He deserves the highest praise possible.
    Oct 03, 2022
    Dr. Masharani is fantastic and has helped me to improve my diabetes care through empowerment of my own abilities.
    Sep 25, 2022
    If every doctor was as kind empathic and smart as Dr. Masharani we would all be in a better place as humans.
    Sep 22, 2022
    Dr Masharani is an excellent doctor. I am truly blessed to have him.
    Sep 19, 2022
    Dr. Masharani is a wonderful mix of knowledgeable professional kind and polite
    Aug 28, 2022
    Dr. Masharani is an amazing compassionate clinician. I am grateful for his treatment
    Aug 21, 2022
    Dr Masharani was very good explaining my medication and adjusting it aporopriately
    Aug 09, 2022
    I had one concern that I wanted to discuss. I have metabolic issues In that my body doesn't assimilate vitamins & minerals from the food I eat and the supplements I take. Dr Masharani specializes in this metabolic field. Can we please schedule a appointment for me
    Jul 17, 2022
    Most excellent Endo I ever had.
    May 28, 2022
    Very good
    Apr 28, 2022
    Apr 28, 2022
    The care provider was very thorough
    Apr 16, 2022
    I travel 4 1/2 hours just to see this provider that's how wonderful he is.
    Apr 12, 2022
    I felt the Clinician blamed me for my cptsd. I left the appointment feeling I was blamed for my problem control my blood glucose. He said I am not going to be able to use a pump until I get my CPTSD under control. I am In an anxiety group and have been for several years now. I feel I am making progress. My current blood glucose problems have more to do with the fact that I started to take steroids for colitis. Dr did not address this aspect.
    Apr 01, 2022
    I always have pleasant appointments with Dr. Masharani! He's always willing to listen. My appointment was scheduled at 1:30pm but he made so much effort to see me earlier despite his full busy schedule. When I was having trouble with my TSH levels he was quick on correcting it. He really does go above and beyond!
    Mar 12, 2022
    Dr. Masharani is very nice funny and caring. We always enjoy seeing him. He's very concise and detailed in his instructions. Thank you for your care!
    Mar 12, 2022
    Dr. Masharani is one of the best doctors at UCSF that I have encountered. He is up to date on the latest diabetes management he provides options and recommendations but at the same time very respectful of the patient's desires. He is top notch.
    Mar 05, 2022
    Dr. Masharani's office called me with just 10 minutes notice to do a video visit in response to an email I sent asking questions. During our video visit Dr. Masharani cut me off while I was describing my thyroid symptoms and essentially mansplained to me about a condition I've been dealing with for nearly 20 years. It was frustrating he didn't have my background info and was placating me about my medication concerns.
    Feb 27, 2022
    Dr. Masharani is one of the best physicians caring for me. I appreciate him very much and always come out of the visits well informed and positive.