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Dr. Umesh Masharani is an endocrinologist who cares for patients with diabetes and thyroid disorders. He also has an endocrine faculty practice.

Masharani's research focuses mainly on diabetes, with a particular interest in insulin resistance. He collaborates with colleagues in the family medicine departments to examine the relationships among glucose control, depression and psychosocial stress in people with diabetes. He is part of the islet auto-transplantation group, which has an active program managing patients who require surgical removal of the pancreas for chronic pancreatitis and are candidates for islet auto-transplant, a procedure that allows the patient's body to continue producing insulin. The islet transplant group is also studying donor islet transplants as a treatment for type 1 diabetes.

In addition, Masharani is collaborating with Dr. George Brooks, a professor of integrative biology at the University of California, Berkeley, to examine the impact of exercise and aging on mitochondrial function.

Masharani earned his bachelor's degree in physiological sciences at the University of Oxford. He earned his medical degree at Middlesex Health in London. He completed his residency in internal medicine at University Hospitals Birmingham NHS Foundation Trust in Birmingham, England. He completed a fellowship in endocrinology at UCSF.

  • Education

    University of Oxford, BA, Physiological Sciences, 1979

    Middlesex Health, MBBS, 1982

  • Residencies

    University Hospitals Birmingham, Internal Medicine, 1985

  • Fellowships

    UCSF, Endocrinology, 1993

  • Board Certifications

    Endocrinology Diabetes and Metabolism, American Board of Internal Medicine

  • Academic Title


  • Languages


Where I see patients (7)

    My reviews


    Overall Experience
    346 Ratings
    About our process
    Apr 01, 2022
    I always have pleasant appointments with Dr. Masharani! He's always willing to listen. My appointment was scheduled at 1:30pm but he made so much effort to see me earlier despite his full busy schedule. When I was having trouble with my TSH levels he was quick on correcting it. He really does go above and beyond!
    Mar 12, 2022
    Dr. Masharani is very nice funny and caring. We always enjoy seeing him. He's very concise and detailed in his instructions. Thank you for your care!
    Mar 12, 2022
    Dr. Masharani is one of the best doctors at UCSF that I have encountered. He is up to date on the latest diabetes management he provides options and recommendations but at the same time very respectful of the patient's desires. He is top notch.
    Mar 05, 2022
    Dr. Masharani's office called me with just 10 minutes notice to do a video visit in response to an email I sent asking questions. During our video visit Dr. Masharani cut me off while I was describing my thyroid symptoms and essentially mansplained to me about a condition I've been dealing with for nearly 20 years. It was frustrating he didn't have my background info and was placating me about my medication concerns.
    Feb 27, 2022
    Dr. Masharani is one of the best physicians caring for me. I appreciate him very much and always come out of the visits well informed and positive.
    Jan 04, 2022
    Visit was very productive regarding my issue's and a plan was provided.
    Dec 21, 2021
    I have seen Dr. Masharani for many years. I love how he pauses to think lets me know what he Is considering then asks what I think. He is an extraordinary doctor.
    Dec 07, 2021
    Dr. Masharani has provided exceptional care and follow up while determining the plan of care
    Nov 24, 2021
    Dr. Masharani is an outstanding clinician with deep skill and knowledge. He also cares deeply about his patients which is so appreciated.
    Oct 21, 2021
    Dr. Masharani is clear and kind and explains his thought process in the plan of care
    Aug 03, 2021
    Dr. Masharani is extremely thorough in his care and informative and thoughtful as to his treatment plan for my health condition.
    Jun 26, 2021
    The doctor showed great interest empathy and understanding of my situation; this was the first time I had a consultation with him. He took ample time to ask about my and my family's medical history in order to get a good understanding of my own situation.
    Jun 25, 2021
    be best
    Jun 15, 2021
    just a want to hear from his scheduler
    Jun 13, 2021
    The provider was extremely rude and condescending. He was angry at me for not getting my test done at UCSF and he told me that I had to do what treatment he told me to do even though I was concerned about it. His bedside manner is terrible and I will not be seeing him again.
    May 29, 2021
    very good
    May 24, 2021
    Dr Umesh Masharani is one of the most loving and caring MDs I've experienced in my 30 years of care at UCSF. clear passionate bright talented and a wonderful listener. Put the pt first and is in my mind a model for how a care provider should treat a pt.
    May 23, 2021
    Appointment regarding post-lung transplant plan with Tymlos mailed orders for bone density test and talked about the post-transplant diabetes. Huge appointment with lots of important information.
    May 20, 2021
    I was genuinely surprised as to how clear and descriptive Dr. Masharani was and the time he put in providing an explanation. I also would like to commend how quickly he set up an appt when I was concerned of the side effects. I have had many doctors at ucsf and he is by far the best doctor I have come across.
    May 08, 2021
    Dr. Masharani is an outstanding endocrinologist and always shows concern for my health and gives me excellent advice.
    May 02, 2021
    Provider suggested I see a gynecologist about hormone issues. Nothing was too out of whack for the provider an endocrinologist to get involved.
    Apr 18, 2021
    Excellent caring wonderful always.
    Apr 08, 2021
    Dr Masharani is excellent!
    Feb 22, 2021
    The doctor was very helpful and seemed very concerned with my situation. The entire staff were great!!!
    Feb 21, 2021
    very good
    Feb 11, 2021
    Dr. Masharani is a great doctor and an outstanding specialist I feel very lucky to be in his care
    Feb 11, 2021
    he is an excellent dr who I entrust with my life
    Jan 27, 2021
    Great listener.
    Jan 24, 2021
    Dr. Masharani is caring and kind and he's very knowledgeable about the proper maintenance of type 1 diabetes.
    Nov 17, 2020
    Dr. Masharani is easily the best endocrinologist I had so far in matching his experience to my reality! The only problem is he is so awesome that everyone wants his time which is understandable. I do appreciate him fitting me in as well. TY!
    Nov 06, 2020
    Dr. MASHARANI has been an outstanding provider. His knowledge is world class and his attention and kindness so appreciate. We are fortunate to have him as a resource.
    Oct 31, 2020
    Dr. Masharani is the best!
    Oct 19, 2020
    Again sound quality made it difficult to have a good discussion or to follow provider's instructions.
    Oct 03, 2020
    Dr. Masharani is always professional patient and helpful.
    Sep 23, 2020
    He/ She are both great very professional & friendly recommendable
    Sep 21, 2020
    The experience was a good one better than an in person appointment as there were no distractions . The concentration was on background my medical issues.
    Sep 05, 2020
    I would highly recommend anyone with diabetes to consult Dr. Masharani about diabetic treatment and control.
    Sep 04, 2020
    Again Dr. Masharani is very personable has excellent bedside manners thorough in his explanations of the medical options risks and benefits. I am very grateful to be his patient.
    Sep 02, 2020
    Overall the experience was fine but I want the next visit in person.
    Aug 04, 2020
    Dr. Masharani had a caring and thoughtful manner
    Jul 28, 2020
    It was challenging to understand Dr. Masharani. The connection was poor and I had to ask him to repeat thoughts and instructions fairly often to make sure I understood. This was definitely a problem with the app.
    Jul 12, 2020
    He wanted time to review my MRI fractures and consider which medication moving forward.
    Jul 12, 2020
    Excellent Doctor and I highly recommend him.
    Jun 26, 2020
    dr Masharani is an excellent doctor with great bedside manner. very knowledgeable and someone I trust with my healthcare and transplanted kidney in regards to my diabetes
    May 23, 2020
    I have already referred someone to this Dr

    Selected research