Dr. Umesh Masharani is an endocrinologist who cares for patients with diabetes and thyroid disorders. He also has an endocrine faculty practice.

Masharani's research focuses mainly on diabetes, with a particular interest in insulin resistance. He collaborates with colleagues in the family medicine departments to examine the relationships among glucose control, depression and psychosocial stress in people with diabetes. He is part of the islet auto-transplantation group, which has an active program managing patients who require surgical removal of the pancreas for chronic pancreatitis and are candidates for islet auto-transplant, a procedure that allows the patient's body to continue producing insulin. The islet transplant group is also studying donor islet transplants as a treatment for type 1 diabetes.

In addition, Masharani is collaborating with Dr. George Brooks, a professor of integrative biology at the University of California, Berkeley, to examine the impact of exercise and aging on mitochondrial function.

Masharani earned his bachelor's degree in physiological sciences at the University of Oxford. He earned his medical degree at Middlesex Health in London. He completed his residency in internal medicine at University Hospitals Birmingham NHS Foundation Trust in Birmingham, England. He completed a fellowship in endocrinology at UCSF.

  • Education

    University of Oxford, BA, Physiological Sciences, 1979

    Middlesex Health, MBBS, 1982

  • Residencies

    University Hospitals Birmingham, Internal Medicine, 1985

  • Fellowships

    UCSF, Endocrinology, 1993

  • Board Certifications

    Endocrinology Diabetes and Metabolism, American Board of Internal Medicine

  • Academic Title


  • Languages


Clinics I work with

Center for Neuroendocrine Tumors

Bakar Precision Cancer Medicine Building

1825 Fourth St.
San Francisco, CA 94158

Diabetes Clinic at Parnassus

400 Parnassus Ave., Suite A-550
San Francisco, CA 94143

Diabetes Teaching Center

400 Parnassus Ave., Suite A-550
San Francisco, CA 94143

Endocrinology Clinic at Parnassus

400 Parnassus Ave., Suite A-550
San Francisco, CA 94143

Pancreas Center

Bakar Precision Cancer Medicine Building

1825 Fourth St., Fourth Floor
San Francisco, CA 94158

Thyroid Clinic

400 Parnassus Ave., Suite A-550
San Francisco, CA 94143

Total Pancreatectomy – Islet Auto-Transplant (TP-IAT) Clinic

400 Parnassus Ave., 7th Floor
San Francisco, CA 94143-0780

My reviews


Overall Experience
380 Reviews
Explained things in a way that was easy to understand
379 Reviews
Did the doctor pay attention to your concerns
377 Reviews
Gave easy to understand instructions about taking care of health problems or concerns
359 Reviews
Knew the important information about your medical history
378 Reviews
The provider showed respect for what you had to say
375 Reviews
The provider spent enough time with me
377 Reviews