
Head & Neck Cancer
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Why choose UCSF Health for head and neck cancer treatment?
UCSF Health is defining a new standard of care for head and neck cancers. We use groundbreaking research and clinical trials to help people live longer, healthier lives. Our experts are known for their ability to diagnose and treat rare and complex diseases, including salivary gland cancers, skull base tumors and nasopharyngeal cancers (upper throat or behind the nose).
We also offer a broad range of surgeries for benign (noncancerous) and malignant (cancerous) tumors of the head and neck. These tumors can affect your appearance and vital functions, such as speaking, breathing and swallowing. Whenever possible, we choose less invasive procedures to minimize side effects and preserve your quality of life.
Why choose UCSF Health for head and neck cancer treatment?
UCSF Health is defining a new standard of care for head and neck cancers. We use groundbreaking research and clinical trials to help people live longer, healthier lives. Our experts are known for their ability to diagnose and treat rare and complex diseases, including salivary gland cancers, skull base tumors and nasopharyngeal cancers (upper throat or behind the nose).
We also offer a broad range of surgeries for benign (noncancerous) and malignant (cancerous) tumors of the head and neck. These tumors can affect your appearance and vital functions, such as speaking, breathing and swallowing. Whenever possible, we choose less invasive procedures to minimize side effects and preserve your quality of life.
National recognition
We are consistently ranked among the top hospitals in the nation for both cancer and ear, nose and throat care by U.S. News & World Report.Second opinions
Our doctors expertly diagnose challenging and complex tumors and can often provide alternative treatment options not available at other institutions.High-volume program
Our head and neck cancer doctors treat a high number of patients each year, giving us a level of experience that's unmatched in the Bay Area.Whole-person care
Our speech-language pathologists help people regain their ability to speak and swallow after cancer treatment, so you can feel more like yourself.
Our collaborative approach to head and neck cancer treatment
Head and neck tumors are complex conditions that require coordinated care from a comprehensive team of specialists. At UCSF Health, our teams meet weekly to discuss each patient's diagnosis and plan the right timing and sequence of treatments.
You receive care from experts in:
Head and neck surgery
Otolaryngology
Medical and radiation oncology
Facial plastic and reconstructive surgery
Speech-language pathology
Dental oncology
Neuroradiology
Head and neck pathology
Oral medicine and oral surgery
Maxillofacial prosthodontics
Depending on your needs, we also partner with providers in:
Nutrition
Psycho-oncology
Melanoma oncology
Oculofacial plastic surgery
Neurosurgery
Orthopedic oncology
Head and neck cancer diagnosis
We provide timely, accurate diagnoses so you can start treatment promptly. You can often see multiple specialists and get the tests you need, such as imaging exams or a needle biopsy, in a single appointment. We also offer the convenience of in-office ultrasounds, so you don't need to schedule a separate visit.
Head and neck cancer treatment
Our experts offer many head and neck cancer treatments, and often combine therapies, to help you achieve the best possible outcome.
Head and neck medical oncology
Medical oncologists use drugs, such as chemotherapy, immunotherapy and targeted therapy, to fight cancer. At UCSF Health, we use sophisticated molecular testing to find out which therapies are most likely to be effective for the type of cancer you have.
We offer:
Chemoradiation. This combination of chemotherapy and radiation therapy is a common treatment for head and neck cancer. You may have chemoradiation on its own or after surgery.
Immunotherapy. These treatments harness your immune system to fight cancer. Immunotherapy may improve survival rates and quality of life in people with head and neck cancer that has spread to other areas of the body (metastatic).
Targeted therapy. These treatments interfere with the processes that allow cancer cells to grow and divide. They target specific molecules on cancer cells, making this a highly precise treatment with fewer side effects than chemotherapy or radiation therapy.
Head and neck surgical oncology
UCSF Health head and neck surgeons perform advanced procedures using sophisticated technology, with a special focus on minimally invasive approaches.
We offer:
Transoral robotic surgery (TORS). Surgeons control a robotic arm that allows them to remove tumors in hard-to-reach areas, such as the back of your throat and tongue. They perform this procedure through your mouth, so you don't have visible incisions on your neck or face.
Minimally invasive skull base surgery. Our surgeons perform minimally invasive surgery using an endoscope (thin tube with a light and camera) to remove skull base tumors through your nose. This endonasal approach avoids the need for major open brain surgery.
Thyroid and parathyroid surgery. Our team has the diagnostic expertise to determine when surgery is needed versus when to take a watch-and-wait approach. If you need surgery, we offer minimally invasive procedures whenever possible. During surgery, intraoperative monitoring helps preserve important nerves involved in speaking, breathing and swallowing.
Reconstructive surgery. Our facial plastic and reconstructive surgeons use advanced techniques, such as microvascular surgery and facial reanimation, to rebuild areas of your head or face affected by tumors.
At UCSF Health, we use state-of-the-art radiation delivery systems. Our technology includes a linear accelerator (LINAC) that delivers intensity-modulated radiation therapy (IMRT).
This approach adjusts the intensity of the radiation to precisely target head and neck tumors, while sparing healthy tissue. Your care plan may include radiation therapy in combination with surgery or medical therapies.
Before radiation treatment, you meet with specialists in oral and dental oncology. They help prevent and treat potential side effects of radiation near your mouth and teeth, including dry mouth, infections and tooth decay. They may recommend fluoride rinses, dental cleanings, tooth extractions or other preventive treatments to help keep your mouth healthy.
Locations
Providers
Excellence in patient care

Best in California and No. 7 in the nation for cancer care
Related conditions & treatments
Conditions
- Laryngeal Cancer
- Melanoma
- Mouth Cancer
- Neoplasm of Salivary Gland
- Sinus Cancer
- Parathyroid Mass
- Throat Cancer
- Thyroid Cancer
Treatments
- Chemoradiation
- Facial Plastic Surgery
- Intensity-Modulated Radiation Therapy
- Microvascular Surgery
- Transoral Robotic Surgery (TORS)
Clinical trials
Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and NeckOpens in a new window
Intratumoral CD3+ T-cells will be identified by immunohistochemistry in pre- and post-treatment tumor specimens. The analysis population for the primary outcome will be all patients who received at least 2 weeks of neoadjuvant the...Evaluating a Low-Cost Therapeutic Device in Managing Head and Neck Cancer Patients With Radiati...Opens in a new window
The mean change in MIO from baseline to end of treatment at 6 weeks will be reported
Explore what we do
We offer a variety of specialized services to help you manage every aspect of head and neck cancer.Oral dysplasia
Voice and swallowing
Accreditations & memberships

National Cancer Institute
The National Cancer Institute has designated UCSF Health a comprehensive cancer center, its highest ranking. This designation is awarded to centers that demonstrate scientific excellence and the ability to conduct cancer research across many disciplines.
Commission on Cancer
UCSF Health's cancer programs have been accredited by the American College of Surgeons' Commission on Cancer (CoC) since 1933. The CoC is a consortium of groups dedicated to improving cancer patients' survival and quality of life via research, education and better medical care.
National Comprehensive Cancer Network
UCSF is a member of the National Comprehensive Cancer Network, an alliance of the world's top cancer centers. The network brings together leaders in treatment and research to improve the quality, effectiveness and efficiency of cancer care.
Research initiatives
UCSF Helen Diller Family Comprehensive Cancer Center ResearchOpens in a new window
UCSF is home to a range of research initiatives aimed at improving outcomes for cancer patients everywhere. This includes research on topics such as immunotherapy, BRCA mutations and molecular diagnostic testing.











