Metabolic Bone Clinic

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The Metabolic Bone Clinic in the UCSF Division of Endocrinology and Metabolism is a unique resource that focuses on the diagnosis and care of patients with inherited, rare or unusually complicated bone conditions. Some of these conditions include:

  • Congenital diseases (diseases that are present at birth) and skeletal dysplasias such as fibrodysplasia ossificans progressiva (FOP), fibrous dysplasia (MAS/FD), osteogenesis imprefecta (OI) and spondyloarthropathies
  • Endocrine and metabolic bone diseases that occur with conditions such as hyperparathyroidism, mitochondrial diseases and enzyme deficiencies
  • Unusually severe osteoporosis resulting from cancer treatment or organ transplant, or other conditions that result in abnormal bone loss or gain

Our team works closely with other divisions at UCSF, including medical genetics, orthopedics, nephrology, rheumatology, dentistry and craniofacial surgery to provide the most comprehensive care possible to our patients.

You'll need a referral from your primary care provider or specialist to make an appointment. Once you have the referral, please call the number below.

Getting Here

Metabolic Bone Clinic
400 Parnassus Ave., Fifth Floor, Suite A-550
San Francisco, CA 94143
Phone: (415) 353-2350
Fax: (415) 353-2337

Hours: First Monday of each month, second and fourth Tuesday of every month

What to Bring

  • Health insurance information including authorizations or referrals
  • List of prescription medications and dosages
  • List of medications that you're allergic to
  • List of questions you may have
  • Recent test results related to your condition
  • Paper and pencil to take notes

Access Your Health Information Online

This clinic uses UCSF MyChart, an online patient service. Message your provider, request medication refills, view some test results and more.

Learn more about UCSF MyChart

Research and Clinical Trials


Parking at Parnassus

Public parking for an hourly fee at UCSF Medical Center is available in the seven-level Millberry Union Garage at 500 Parnassus Ave. There are two garage entrances — one on the north side of Parnassus Avenue and another on Irving Street, just east of Third Avenue.

Another garage with an hourly fee, at 350 Parnassus Ave., is open Monday to Friday from 6 a.m. to 10 p.m.

Metered street parking is rarely available.

Patients being admitted to the hospital may be dropped off at the circular driveway leading to the main entrance at 505 Parnassus Ave. This area also may be used to pick up patients who are being discharged.

For more information about parking at Parnassus, call Campus Parking Services at 476-2566.

Valet Parking Service

Valet parking service is available at the Ambulatory Care Center (ACC) at 400 Parnassus Ave. from 8 a.m. to 3 p.m. The valet service is free but patients must pay regular parking fees. For more information about the valet service, call (415) 476-6200.

A UCSF "greeter" also is available at the ACC from 8 a.m. to 5 p.m. to assist patients find their way.

Public Transportation


UCSF Medical Center is accessible via Muni streetcar line N-Judah*, which stops at Second Avenue and Irving Street, and the following Muni bus lines, which stop in front of the hospital:

  • 43-Masonic*
  • 6-Parnassus

For more information about Muni visit,

* Wheelchair accessible bus routes


To make an appointment, please provide:

  • A referral request from your primary care provider, with a brief synopsis of the reason for the referral

Depending on your individual case, we may also ask you to provide:

  • Summary of your medical history
  • List of your medications
  • Summary of your previous treatment for bone disease
  • Imaging studies related to your bone condition
  • Bone density (DEXA scan) for osteoporosis/osteopenia
  • CT or MRI of any affected bones or the skull
  • Results from any prior radiology imaging tests — please bring a CD disc with the images for us to review in person
  • Results from any lab tests related to your condition from the past three months
  • If you have had genetic testing done, a copy of the original genetic test results
  • A list of all your prior physicians
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Steven Harris
Steven Harris, MD
Edward Hsiao
Edward Hsiao, MD
Dolores Shoback
Dolores Shoback, MD