Multiple Sclerosis and Neuroinflammation Center
The UCSF Multiple Sclerosis and Neuroinflammation Center is one of California's premier centers for treating adult and pediatric patients with multiple sclerosis (MS) and other inflammatory diseases of the nervous system. Our renowned team of experts provides personalized, comprehensive care that helps patients manage their symptoms and maximize their quality of life at all stages of their condition. We aim to help our patients stay as active, healthy and independent as possible. Patients and their families also have access to education and support resources.
In addition to treating patients, our providers conduct research on potential new therapies. You may be offered the opportunity to participate in a clinical trial.
We are part of the UCSF Weill Institute for Neurosciences.
MD, PhD, MASNeurologist
NP, MSNNurse practitioner
Emmanuelle L. Waubant
Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset
Comparison of intrathecal synthesis of gammaglobulins in treatment-naïve relapsing MS and clinically isolated syndrome participants before and after 3 years of treatment with ocrelizumab. Intrathecal synthesis is measured by eithe...
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
NEP is defined as no progression sustained for at least 24 weeks on all of the following three components (confirmed disability progression [CDP]; ≥20% increase in timed 25-foot walk test [T25FWT]; ≥20% increase in nine-hole peg t...
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
Time to sustained disability progression is measured by the Expanded Disability Status Scale plus (EDSS+): a composite endpoint that includes EDSS change (change at any 6 month time point of > 1.0 point if baseline EDSS is < 5.5 o...
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
To evaluate the efficacy of clemastine relative to placebo for reducing P100 latencies on full field transient pattern reversal visual evoked potentials. Measure will be reported as difference in P100 latency from baseline to 9 mo...
Ocrelizumab in Breastmilk
Levels of ocrelizumab (μg/mL) in the breastmilk of women at the selected timepoints before and after infusion (hour 8, hour 24, day 7, day 20, day 30, day 60, and day 90). If receiving two infusions the samples will be as follows:...
Non-invasive Transcranial Electrical Stimulation in MS
Symbol Digit Modalities Test (SDMT) score will be used to measure processing speed. SDMT measures the time to pair abstract symbols with specific numbers. The test requires visuoperceptual processing, working memory, and psychomot...
Bazedoxifene Acetate as a Remyelinating Agent in Multiple Sclerosis
The primary objective is to evaluate the efficacy of BZA relative to placebo for reducing P100 latencies on full field transient pattern reversal visual evoked potentials (VEPs). In response to a visual stimulus, cortically genera...
Melatonin for Sleep in MS
Total sleep time (time in bed spent sleeping after "lights off")
Fecal Microbiota Transplantation (FMT) of FMP30 in Relapsing-Remitting Multiple Sclerosis
Proportion of subjects who complete the study protocol
Computerized Cognitive Training in MS
Processing speed is being measured by the Symbol Digit Modalities Test (SDMT) score. SDMT measures the time to pair abstract symbols with specific numbers. The test requires visuoperceptual processing, working memory, and psychomo...
Awards & recognition
Best hospital in Northern California
Best in the West in neurology & neurosurgery
Case Management and Social Work
Connect with a team that can help you find resources, solve problems and advocate for you during treatment at UCSF.
Mindfulness-Based Stress Reduction Class
This eight-week UCSF class teaches mindfulness practices, such as meditation and body awareness, that can reduce stress and improve your overall health.
Neurology Support Groups
The UCSF Aneurysm and Arteriovenous Malformation (AVM) Support Group encourages all patients with these blood vessel disorders to join. Find more info here.
We welcome feedback about your experience at UCSF Health. Find out how to contact us with comments, questions or concerns.
Spiritual Care Services
Chaplains representing many faiths are available around the clock to provide support, comfort and counsel to patients, families and caregivers. Learn more.
Plan your visit
What to Bring
- Photo I.D.
- Health insurance card
- Insurance authorization, if required
- Doctor's referral, if required
- Recent test results related to your condition
- List of your medications, including dosages, plus any you're allergic to
- List of questions you may have
- Device or paper for taking notes
If you live in another country and are coming to UCSF for medical
treatment, our patient liaisons can help coordinate all aspects of your visit.
UCSF offers language services at no charge for patients with limited
English, as well as for patients who are deaf or have trouble hearing.
Checking into the hospital? Find helpful information by clicking on the relevant “Your Hospital Stay” booklet: Mission Bay, Parnassus or Mount
Your Doctor Visit
See our top 10 tips for making your UCSF doctor’s appointment as stress-free and productive as possible.
Our research initiatives
UCSF Multiple Sclerosis Center Research
The UCSF Multiple Sclerosis Center's research program focuses on investigating potential new treatments and improving understanding of the disease, including the effects of genes, the environment and the immune system.