Dermatology Clinic at Mount Zion

Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen Repository

The primary aim of this study is to identify clinical and biologic characteristics of hidradenitis suppurativa.

Recruiting

Clinical and Biological Characteristics of Hidradenitis Suppurativa

Recruiting

Guselkumab Immunogenetics

Mean change from baseline in percent of lesional CD4+ T effector cells producing IL-17

Recruiting

Immunogenetic Profiling of Dupilumab for the Treatment of Atopic Dermatitis

Percentage change from pre-treatment baseline of CD4+ T effector cells expressing IL-4 at weeks 2, 4, 12 in dupilumab-treated patients.

Recruiting

Predicting Inflammatory Skin Disease Response to IL-23 Blockade

Change in severity and extent of psoriasis (calculated by Psoriasis Area and Severity Index (PASI) score); scale range of 0 to 72, 72 being maximal disease.

Recruiting

Single Cell Genomics of Psoriatic Skin

Recruiting

The Impact of Dupilumab on Quality of Life in Moderate to Severe Atopic Dermatitis Patients

The primary endpoint is the improvement in quality of life measured by change in Psychological General Well-Being scale (PGWB) at Week 16 from baseline. It is a self-reported, 22 item questionnaire, scored 0-5 and summed. PGWB wil...

Recruiting

Clinical Utility of Pediatric Whole Exome Sequencing

Our outcome will be an assessment of clinical utility in patients that receive a positive (pathogenic or likely pathogenic) result. Clinical utility will be measured with a quantitative score based on changes in medical care, such...

Recruiting

Immunogenetic Profiling of Goeckerman Therapy in the Treatment of Psoriasis Vulgaris

Perform quantitative analysis of the immunologic and genetic changes in immune cell populations after treatment with traditional Goeckerman (NBUVB + coal tar), coal tar only, and NB-UVB only, at weeks 2, 4, and 12 compared to base...

Recruiting