
Hematology, Blood & Marrow Transplant, and Cellular Therapies (HBC) Program
The UCSF Hematology, Blood and Marrow Transplant, and Cellular Therapy (HBC) Program is dedicated to providing patients with the most advanced and innovative treatment options, along with compassionate and personalized care. People from throughout the United States and abroad choose our program for its groundbreaking work and for our providers, who specialize in blood disorders and the use of transplantation and cellular therapy.
UCSF is also home to a robust research program. Patients may have the option to participate in novel clinical trials, including studies evaluating the use of targeted therapeutics, new transplantation techniques and immunotherapy treatments, such as tumor vaccines and CAR T-cell therapy.
CAR T-Cell Therapy
CAR T-cell therapy – which uses the patient’s immune system to fight cancer cells – has dramatically changed how blood cancers are treated. Our clinical and research teams are internationally renowned for their pioneering work in cell-based immunotherapy for cancer, and we have been at the forefront of designing new CAR T-cell strategies for treating blood cancers. UCSF was one of the first institutions licensed to offer standard-of-care CAR T cells for young patients with acute lymphocytic leukemia (ALL).
We now offer FDA-approved CAR T-cell therapy to patients with ALL, patients with various forms of non-Hodgkin’s lymphoma, and patients with relapsed and refractory multiple myeloma. Even after resisting all other treatment options or relapsing after standard treatment, those conditions have responded dramatically to CAR T-cell therapy.
In patients with B-cell non-Hodgkin’s lymphoma, B-cell acute lymphoblastic leukemia and mantle cell lymphoma (MCL), CAR T-cell therapy has resulted in long-term remissions and even cures for some. Research is ongoing to increase the number of patients cured and expand the use of CAR T cells to other blood cancers, such as multiple myeloma and Hodgkin’s disease, as well as solid tumors of the breast, prostate, brain, lungs and other organs.
A Comprehensive Cancer Center
As part of the UCSF Helen Diller Family Comprehensive Cancer Center, we offer our patients access to many services, including support groups, exercise and mindfulness classes, psychosocial support, symptom management and much more.
Parker Institute for Cancer Immunotherapy
Our program is a member of the Parker Institute for Cancer Immunotherapy, a consortium made up of 10 of the world’s leading cancer centers. Its mission is to turn cancer into a curable disease by accelerating the development of breakthrough immune therapies.
Our locations
Patient education
Our team
Clinical trials
Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin...
All subjects enrolled in this phase I study who actually received study drug (anti-CD19 CAR-T infusion) will be included in the analysis. Proportion of participants with treatment-emergent adverse events of CAR-T in B-cell NHL, as...
Recruiting
Daratumumab, Azacitidine, and Dexamethasone for Treatment of Patients With Recurrent or Refract...
ORR is defined as stringent complete response (sCR) + complete response (CR) + very good partial response + partial response (PR) as best response using International Myeloma Working Group (IMWG) Uniform Response Criteria for all ...
Recruiting
Rankings & achievements
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Best hospital in Northern California
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Best in Northern California in cancer care
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blood and marrow transplants performed each year
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Founded in 1986
Accreditations & memberships
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National Cancer Institute
The National Cancer Institute has designated UCSF a comprehensive cancer center, its highest ranking. This designation is awarded to centers that demonstrate scientific excellence and the ability to conduct cancer research across many disciplines.
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Commission on Cancer
UCSF's cancer programs have been accredited by the American College of Surgeons' Commission on Cancer (CoC) since 1933. The CoC is a consortium of groups dedicated to improving cancer patients' survival and quality of life via research, education and better medical care.
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National Comprehensive Cancer Network
UCSF is a founding member of the National Comprehensive Cancer Network, an alliance of the world’s top cancer centers. The network brings together leaders in treatment and research to improve the quality, effectiveness and efficiency of cancer care.
Support services
Plan your visit
What to Bring
- Photo I.D.
- Health insurance card
- Insurance authorization, if required
- Doctor's referral, if required
- Recent test results related to your condition
- List of your medications, including dosages, plus any you're allergic to
- List of questions you may have
- Device or paper for taking notes

International Services
If you live in another country and are coming to UCSF for medical
treatment, our patient liaisons can help coordinate all aspects of your visit.

Interpreters
UCSF offers language services at no charge for patients with limited
English, as well as for patients who are deaf or have trouble hearing.

Hospital Stays
Checking into the hospital? Find helpful information by clicking on the relevant “Your Hospital Stay” booklet: Mission Bay, Parnassus or Mount
Zion.

Your Doctor Visit
See our top 10 tips for making your UCSF doctor’s appointment as stress-free and productive as possible.
Learn moreRelated clinics
Our research initiatives
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UCSF Helen Diller Family Comprehensive Cancer Center Research
UCSF is home to a range of research initiatives aimed at improving outcomes for cancer patients everywhere. This includes research on topics such as immunotherapy, BRCA mutations and molecular diagnostic testing.